Receptor Autoradiography
Principles and Practice
Published on 31. January 1994
Book
Hardback
352 pages
978-0-19-262209-9 (ISBN)
Description
Receptor autoradiography is a powerful aand robust technique that is widely used to localize and characterize peptide and neurotransmitter binding sites. Its extensive use reflects the utility of technique and the important advantages it offers over conventional biochemical procedures. This book aims to make receptor autoradiography more accesible by giving a detailed account of the methodology and its application in the analysis of receptors in the brain and peripheral organs. These examples are not exaustive but illustrate the versatility of the technique as well as its potential pitfalls. The book provides an introduction to the receptor concept and gives detailed informaitn on the theory and procedures involved in the auto radiographic localization and quantification of radiolabelled ligand binding sites. The book should be useful to neuroscientists, pharmacologists, histochemists, neuropathologists and scientists in the pharmaceuticals industry.
More details
Series
Language
English
Place of publication
Oxford
United Kingdom
Target group
College/higher education
Professional and scholarly
Illustrations
colour plates, halftones, line figures, tables, bibliography
Dimensions
Height: 230 mm
Width: 150 mm
Weight
800 gr
ISBN-13
978-0-19-262209-9 (9780192622099)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Classification
Content
An introduction to receptors, C.W. Taylor and S.C.R. Lummis; background to receptor mapping and future trends, M.J. Kuhar; analysis of receptors by radioligand binding, M. Keen and J. MacDermot; autoradiographic techniques, A.L. Hudson; in vitro autoradiographic localizaiton and characterization of binding sites, J. Wharton et al; quantitative analysis of radioligand binding autoradiographs, D.G. Baskin; autoradiographic localization of receptors at the electron microscopic level, A. Beaudet; analysis of receptor expression by in situ hybridization histochemistry, G. Mengod and and T. Vilaro; autoradiographic analysis of excitory amino-acid receptor, D.T. Monaghan; autoradiography of 5-HT receptors, C. Waeber and J.M. Palacios; autoradiographic visualization of dopaminergic receptors, M.S. Lidow; autoradiographic analysis of adenosine receptors, J.-L. Daval; neuropeptide and growth factor receptor autoradiography, R. Quiron et al; neuronal nicotinic acetycholine acetylcholine receptors, E.S. Deneris; localization and regulation of B-adrenoceptor subtypes.