Bound Carbohydrates in Nature
Published on 17. February 1994
Book
Paperback/Softback
128 pages
978-0-521-44743-0 (ISBN)
Description
This 1994 book is based on a series of six lectures delivered at the University of Sienna under the auspices of the Lezioni Lincee. The content of the book reflects and delineates the author's career in biochemical research. The lectures revolve around the special role which bound carbohydrates play in nature. Also discussed are the properties of membrane glycoproteins, involved in the resistance of cells to drugs. The metabolism of sugars and sialic acids, which form a pivotal role in the author's research, are covered in detail. The book chronicles just some of the huge advances which have been made in biochemistry over the past few decades and will prove an invaluable and entertaining first hand account for researchers and graduate students.
More details
Series
Language
English
Place of publication
Cambridge
United Kingdom
Target group
Professional and scholarly
Product notice
Paperback (trade)
Illustrations
7 Tables, unspecified; 30 Line drawings, unspecified
Dimensions
Height: 216 mm
Width: 140 mm
Thickness: 7 mm
Weight
172 gr
ISBN-13
978-0-521-44743-0 (9780521447430)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Person
Content
1. Introduction, history, microheterogeneity of bound carbohydrates; function of bound carbohydrates; inducible changes in bound carbohydrates; programmed changes in bound carbohydrates; a possible role for bound carbohydrates; 2. Sialic acids; distribution of sialic acids in nature; the metabolism of hexamines and sialic acids; metabolic control of hexosamines and sialic acids; asparagine N-glycosylation; processing of lysomal enzymes; biosynthesis of O-linked oligosaccarides; modification of sialic acids; sialidases; genetic metabolic disorders involving sialic acids, glycosidases, bound carbohydrates in malignancy; 3. Multidrug resistance, properties of P-glycoprotein; lysomes and multidrug resistance; kinetics of influx and efflux of drugs, modulation of multidrug resistance; the role of lipids in the accumulation of drugs by MDR cells; P-170 and membrane lipids; Overview.