
Small Molecule - Protein Interactions
Springer (Publisher)
Published on 25. December 2012
Book
Paperback/Softback
XV, 228 pages
978-3-662-05316-4 (ISBN)
Description
Based on the international workshop on 'Small Molecule - Protein Interactions' held in Berlin, April 24-26, 2002, researchers from industry and academic laboratories describe novel and efficient ways selecting promising new drug targets and developing small molecule inhibitors against them. The structure of the book corresponds to the different aspects of the drug discovery process. All chapters are written by leading experts in the field, who present and discuss the most recent state-of-the-art tools and techniques for the development of novel drugs. The value of the book lies in surveying and summarizing the approaches taken by different companies and institutions giving the reader a balanced view on the use of the latest techniques on the one hand and experience-based assistance in selecting appropriate tools for their own work on the other hand.
More details
Series
Edition
Softcover reprint of the original 1st ed. 2003
Language
English
Place of publication
Berlin
Germany
Publishing group
Springer Berlin
Target group
Professional and scholarly
Research
Illustrations
43 s/w Abbildungen, 20 farbige Abbildungen
XV, 228 p. 63 illus., 20 illus. in color.
Dimensions
Height: 0 mm
Width: 0 mm
Weight
329 gr
ISBN-13
978-3-662-05316-4 (9783662053164)
DOI
10.1007/978-3-662-05314-0
Schweitzer Classification
Other editions
Additional editions

Herbert Waldmann | Marcus Koppitz
Small Molecule - Protein Interactions
E-Book
03/2013
Springer
€96.29
Available for download

Herbert Waldmann | Marcus Koppitz
Small Molecule - Protein Interactions
Book
03/2003
Springer
€197.94
No shipping information available
Content
1 Drug Discovery Opportunities.- 2 Target Analysis: A Priori Assessment of Druggability.- 3 Drug Discovery at Signaling Interfaces.- 4 Chemical Genomics of Orphan Nuclear Receptors.- 5 High-Throughput X-Ray Techniques and Drug Discovery.- 6 NMR in Medicinal Chemistry.- 7 Creating Knowledge from High-Throughput Screening Data.- 8 From Structure to Recognition Principles: Mining in Crystal Data as a Prerequisite for Drug Design.- 9 Practical Database Screening with Docking Tools.- 10 De Novo Design Methods.- 11 From Protein Domains to Drug Candidates - Natural Products as Guiding Principles in Compound Library Design and Synthesis.- 12 Discovery of New MCRs, Chemical Evolution and Lead Optimization.- 13 The Impact of Combinatorial Chemistry on Drug Discovery.- Previous Volumes Published in This Series.