
Endocrine Development / Thyroid Gland Development and Function
Karger, S (Publisher)
1st Edition
Published on 16. August 2007
Book
Hardback
192 pages
978-3-8055-8296-4 (ISBN)
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Description
As is the case in all fields of medicine, developmental endocrinology is now being studied at the molecular level. In this volume world-class researchers review the advances of the past decade in the study of normal and abnormal organogenesis of the thyroid gland and of the ontogeny of its function. They describe human thyroid development and its defects with the help of genetic studies in mouse models. Genetic defects of thyroid hormone synthesis are covered and their clinical relevance debated. The important field of thyroid cancer in the context of spontaneous occurrence and as part of familial neoplasia syndromes is described in detail. Finally, the important problem of environmental iodine deficiency which has emerged as a global public health concern is addressed.
For the first time, a decade of work is presented in a concise and highly readable form. Offering valuable insight both for senior clinicians and graduate students, this publication will be of central interest to basic scientists involved in developmental biology as well as to pediatricians and endocrinologists dealing with patients with congenital disorders of thyroid function.
For the first time, a decade of work is presented in a concise and highly readable form. Offering valuable insight both for senior clinicians and graduate students, this publication will be of central interest to basic scientists involved in developmental biology as well as to pediatricians and endocrinologists dealing with patients with congenital disorders of thyroid function.
More details
Series
Language
English
Place of publication
Basel
Switzerland
Target group
College/higher education
Illustrations
in Color:10 Tables:11
Weight
560 gr
ISBN-13
978-3-8055-8296-4 (9783805582964)
Schweitzer Classification
Persons
Content
Foreword: Savage, M.O.; Preface: Van Vliet, G.; Polak, M.; Disorders of Thyroid Gland Development; Murine Models for the Study of Thyroid Gland Development: De Felice, M.; Di Lauro, R.; Familial Forms of Thyroid Dysgenesis: Castanet, M.; Polak, M.; Leger, J.; Possible Non-Mendelian Mechanisms of Thyroid Dysgenesis: Deladoey, J.; Vassart, G.; Van Vliet, G.; Thyroid Imaging in Children: Garel, C.; Leger, J.; Disorders of Thyroid Function; Clinical and Biological Consequences of Iodine Deficiency during Pregnancy: Glinoer, D.; Ontogenesis of Thyroid Function and Interactions with Maternal Function: Obregon, M.J.; Calvo, R.M.; Escobar del Rey, F.; Morreale de Escobar, G.; New Phenotypes in Thyroid Dyshormonogenesis: Hypothyroidism due to DUOX2 Mutations: Moreno, J.C.; Visser, T.J.; Disorders of Thyroid Hormone Metabolism; Thyroid Hormone Transporter Defects: Gruters, A.; Novel Biological and Clinical Aspects of Thyroid Hormone Metabolism: Dumitrescu, A.M.; Refetoff, S.; Pediatric Thyroid Tumors; Papillary and Follicular Thyroid Cancers in Children: Vasko, V.; Bauer, A.J.; Tuttle, R.M.; Francis, G.L.; Hereditary Medullary Thyroid Carcinoma: How Molecular Genetics Made Multiple Endocrine Neoplasia Type 2 a Paediatric Disease: Szinnai, G.; Sarnacki, S.; Polak, M.; Author Index; Subject Index.