Microarray Analysis on Alzheimer's Disease
An approach towards gene expression study using R Language and Biocondcutor
Published on 12. July 2012
Book
Paperback/Softback
76 pages
978-3-659-17375-2 (ISBN)
Description
Microarray technology is a novel technique to identify the Evaluation of differentially expressed gene.This is very useful for the stastical analysis of DNA chip using different stastical software's.This work is attempted to work on microarray analysis on Alzheimer's disease and identify the differentially expressed gene and their reannotation using R and Biocondcutor.R language is freely available and its latest release is Biocondcutor Software. Here,R language and Biocondcutor software is used for the stastical analysis of hippocampus sample of Alzheimer's disease.The data get normalized using RMA and GCRMA generated different Box plot, Nuse plot, RLE Plot and clustering analysis. Using Biocondcutor different stastical test is a best proof for identify the gene expression level of gene.After annotation identify the gene which were responsible for Alzheimer's disease.The Biocondcutor and R language gives basically identify the main probe which is responsible in that sample for disease and gives the final result which caused the Alzheimer's disease.
More details
Language
English
Place of publication
Germany
Product notice
Paperback (trade)
Unsewn / adhesive bound
Dimensions
Height: 220 mm
Width: 150 mm
Thickness: 6 mm
Weight
131 gr
ISBN-13
978-3-659-17375-2 (9783659173752)
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Schweitzer Classification
Persons
Sweta Tripathi is a Bioinformatician completed her post graduate degree in Bioinformatics from Gujarat University, Ahmedabad, India.Completed Research work on Microarray data Analysis on Alzheimer's disease Using R and Biocondcutor.Now,presently she is working on Drug prediction for the Alzheimer's disease and Web-Development tool.