Personalized Epigenetics
2nd Edition
Published on 18. July 2024
Book
Paperback/Softback
780 pages
978-0-443-23802-4 (ISBN)
Description
Personalized Epigenetics, Second Edition discusses the core translatability of epigenetics to health management of individuals who have unique variations in their epigenetic signatures that can guide both disorder and disease prevention and therapy. Fully updated and revised, this new edition details inter-individual variability in the major epigenetic process in humans consisting of DNA methylation, histone modifications, noncoding RNA, and the diagnostic, prognostic, and therapeutic potential of the field. It also reviews the impact of the environment on epigenetic variations among individuals and the role of pharmacology and drug development in personalized epigenetics.
Most importantly, the text covers personalized epigenetics from a disease-oriented perspective, presenting chapters that provide advances in widespread disorders or diseases, including diabetes, cancer, autoimmune disorders, obesity, cardiovascular diseases, neurological disorders, and pain management.
Most importantly, the text covers personalized epigenetics from a disease-oriented perspective, presenting chapters that provide advances in widespread disorders or diseases, including diabetes, cancer, autoimmune disorders, obesity, cardiovascular diseases, neurological disorders, and pain management.
More details
Series
Edition
2nd edition
Language
English
Place of publication
San Diego
United States
Publishing group
Elsevier Science Publishing Co Inc
Target group
Professional and scholarly
Dimensions
Height: 235 mm
Width: 191 mm
Weight
1620 gr
ISBN-13
978-0-443-23802-4 (9780443238024)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Trygve Tollefsbol
Personalized Epigenetics
E-Book
07/2024
2nd Edition
Academic Press
€170.00
Available for download
Previous edition
Trygve O. Tollefsbol
Personalized Epigenetics
Book
07/2015
Academic Press
€110.50
Shipment within 15-20 days
Person
Dr. Tollefsbol is a Professor of Biology and a Senior Scientist in the Center for Aging, Comprehensive Cancer Center, Nutrition Obesity Research Center, and the Comprehensive Diabetes Center at the University of Alabama at Birmingham (UAB). He is Director of the UAB Cell Senescence Culture Facility which he established in 1999 and a Steering Committee Member of the UAB Center for Aging. Dr. Tollefsbol trained as a Postdoctoral Fellow and Assistant Research Professor with members of the National Academy of Science at Duke University and the University of North Carolina. He earned doctorates in molecular biology and osteopathic medicine from the University of North Texas Health Sciences Center and his bachelor's degree in biology from the University of Houston. He has received prior funding from the NIA, NCI, NHLBI, NIMH and other federal institutes as well as the Glenn Foundation for Medical Research, Susan G. Komen for the Cure, the American Federation for Aging Research (AFAR), and the American Institute for Cancer Research (AICR) among many other sources.
Content
Section I. Overview
1. Epigenetics of Personalized Medicine
Section II. Epigenetic variations Among Individuals
2. Interindividual Variability of DNA Methylation
3. Differences in Histone Modifications Between Individuals
4. Individual Noncoding RNA Variations
5. Personalized Epigenetics: Analysis and Interpretation of DNA Methylation Variation
6. Limitations of Personalized Epigenetic Variation Comparisons
Section III. Technologies for Personalized Epigenetics
7. Personalized Epigenetics Technologies
8. Computational Methods in Epigenetics
Section IV. Diagnostic and Prognostic Epigenetic Approaches to Personalized Medicine
9. Epigenetic Biomarkers in Personalized Medicine
10. Epigenetic 'Fingerprint'
11. Epigenetics of Personalized Toxicology
Section V. Environmental Personalized Epigenetics
12. Environmental Contaminants and Their Relationship to the Epigenome
13. Nutriepigenomics: Personalized Nutrition Meets Epigenetics
Section VI. Pharmacology and Drug Development of Personalized Epigenetics
14. Personalized Pharmacoepigenomics
15. Epigenetics of Personalized Nanomedicine
16. Personalized Medicine and Epigenetic Drug Development
Section VII. Personalized Epigenetics of Disorders and Disease Management
17. Understanding Interindividual Epigenetic Variations in Obesity and Its Management
18. Personalized Epigenetic Management of Diabetes
19. Epigenetics and Personalized Pain Management
20. Epigenetic Modification of miRNAs in Cancer
21. Epigenetics and Chemoresistance: A Personalized Approach to Cancer Therapy
22. Personalized Epigenetics and Neurological Disorders
23. Managing Autoimmune Disorders through Personalized Epigenetic Approaches
24. Cardiovascular Diseases and Personalized Epigenetics
Section VIII. Challenges and Future Directions
25. Future Challenges and Prospects for Personalized Epigenetics
1. Epigenetics of Personalized Medicine
Section II. Epigenetic variations Among Individuals
2. Interindividual Variability of DNA Methylation
3. Differences in Histone Modifications Between Individuals
4. Individual Noncoding RNA Variations
5. Personalized Epigenetics: Analysis and Interpretation of DNA Methylation Variation
6. Limitations of Personalized Epigenetic Variation Comparisons
Section III. Technologies for Personalized Epigenetics
7. Personalized Epigenetics Technologies
8. Computational Methods in Epigenetics
Section IV. Diagnostic and Prognostic Epigenetic Approaches to Personalized Medicine
9. Epigenetic Biomarkers in Personalized Medicine
10. Epigenetic 'Fingerprint'
11. Epigenetics of Personalized Toxicology
Section V. Environmental Personalized Epigenetics
12. Environmental Contaminants and Their Relationship to the Epigenome
13. Nutriepigenomics: Personalized Nutrition Meets Epigenetics
Section VI. Pharmacology and Drug Development of Personalized Epigenetics
14. Personalized Pharmacoepigenomics
15. Epigenetics of Personalized Nanomedicine
16. Personalized Medicine and Epigenetic Drug Development
Section VII. Personalized Epigenetics of Disorders and Disease Management
17. Understanding Interindividual Epigenetic Variations in Obesity and Its Management
18. Personalized Epigenetic Management of Diabetes
19. Epigenetics and Personalized Pain Management
20. Epigenetic Modification of miRNAs in Cancer
21. Epigenetics and Chemoresistance: A Personalized Approach to Cancer Therapy
22. Personalized Epigenetics and Neurological Disorders
23. Managing Autoimmune Disorders through Personalized Epigenetic Approaches
24. Cardiovascular Diseases and Personalized Epigenetics
Section VIII. Challenges and Future Directions
25. Future Challenges and Prospects for Personalized Epigenetics