
Development of the Hypothalamus
Morgan & Claypool Publishers
Published on 1. March 2013
Book
Paperback/Softback
83 pages
978-1-61504-512-9 (ISBN)
Description
The involvement of key factors operating independently or in cooperation with others contributes to physical and physiological mechanisms to help engineer a vertebrate hypothalamus. The actions of these key factors influence developmental mechanisms including neurogenesis, cell migration, cell differentiation, cell death, axon guidance, and synaptogenesis. On a molecular level, there are several ways to categorize the actions of factors that drive brain development. These range from the actions of transcription factors in cell nuclei that regulate the expression of developmental genes, to external factors in the cellular environment that mediate interactions and cell placements, and to effector molecules that contribute to signaling from one cell to another. Sexual dimorphism is a hallmark of the vertebrate hypothalamus that may arise as a direct consequence of hormone actions or gene actions. These actions may work through any of the mechanisms outlined above. Given the arrangement of cells in groups within the hypothalamus, cell migration may be one particularly important target for early molecular actions that help build the bases for appropriate functions.
More details
Series
Language
English
Place of publication
San Rafael
United States
Dimensions
Height: 235 mm
Width: 191 mm
Thickness: 6 mm
Weight
176 gr
ISBN-13
978-1-61504-512-9 (9781615045129)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Content
- Acknowledgments
- Introduction
- Compartments in the Diencephalon
- Building a Hypothalamus: Neurogenesis, Cell Survival, and Cell Death
- Building a Hypothalamus: Cell Migration
- The Long and Winding Road of GnRH Neuronal Migration
- Formation of Cell Groups
- Connectivity
- Rebuilding the Hypothalamus
- Conclusion
- Bibliography
- Author Biographies
- Series of Related Interest
- Introduction
- Compartments in the Diencephalon
- Building a Hypothalamus: Neurogenesis, Cell Survival, and Cell Death
- Building a Hypothalamus: Cell Migration
- The Long and Winding Road of GnRH Neuronal Migration
- Formation of Cell Groups
- Connectivity
- Rebuilding the Hypothalamus
- Conclusion
- Bibliography
- Author Biographies
- Series of Related Interest