Patterning in Vertebrate Development
Published on 2. January 2003
Book
Paperback/Softback
264 pages
978-0-19-963869-7 (ISBN)
Description
One of the most fascinating problems in biology is how a single cell, the fertilised egg, gives rise to a new individual. This volume in the "Frontiers in Molecular Biology" series discusses the methods by which cells in distinct regions of an embryo become different, a process known as patterning. Patterning is fundamental to establishing the spatial organisation of the developing embryo. It ensures that all the parts of the body are generated and that they form in exactly the right places. The ultimate in patterning is the formation of precise arrangements of specialised cells and tissues within each organ. Understanding the process of patterning during the embryonic development of vertebrates is a particular challenge for developmental biologists because vertebrates have an intricate and complex anatomy and histology. The first two chapters of "Patterning in Vertebrate Development" are introductory, explaining to the reader the general principles of vertebrate patterning and early embryology. The subsequent chapters address patterning in both nervous system and specific parts of the body.
Reviews / Votes
... a very enjoyable read ... The book has been carefully edited and all chapters link to each other and make appropriate cross-references, which is very helpful to a newcomer to this field. * BioEssays * This book gives a succinct overview of vertebrate patterning and concentrates on areas in which we begin to gain an understanding of the molecular mechanisms involved. The account of some pressing questions currently addressed makes it very up to date and therefore the book should be on the reading list of any student committed to this exciting and rapidly progressing research area. * BioEssays * This book is an interesting and very informative read, and sets out state-of-the-art levels of understanding in the various fields ... For young scientists entering a career in developmental biology, this book should be a focus of interest as well as a spur to dive into a field with many exciting opportunities and challenges for their research. * BSDB Newsletter * ... good cross-referencing between the different chapters. The chapters are also very well referenced and the reader is given both historical and very up-to-date bibliographies to draw from. * BSDB Newsletter *More details
Series
Language
English
Place of publication
Oxford
United Kingdom
Target group
Professional and scholarly
Illustrations
4 pp colour plates, numerous halftones and figures
Dimensions
Height: 245 mm
Width: 189 mm
Thickness: 15 mm
Weight
614 gr
ISBN-13
978-0-19-963869-7 (9780199638697)
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Schweitzer Classification
Person
Professor Cheryll Tickle is a fellow of the Royal Society (FRS FRSE) and a member of the Editorial Board of Differentiation and the Journal of Anatomy. Some of the other contributing authors are senior figures in the field, others are younger scientists
Content
1. Patterning and positional information ; 2. Laying down the body plan ; 3. Patterning the Xenopus embryo ; 4. Somite and axial development ; 5. Vertebrate neurogenesis ; 6. Anteroposterior regionalization of the vertebrate nervous system ; 7. Nervous connections ; 8. Patterning of the neural crest ; 9. Insights into the molecular basis of vertebrate forelimb and hindlimb identity ; 10. Evolutionary aspects of vertebrate patterning