
The Neuroscience of Deep Brain Stimulation
Research and Clinical Applications
Academic Press
Published on 20. February 2026
Book
Paperback/Softback
484 pages
978-0-323-99742-3 (ISBN)
Description
Neuroscience of Deep Brain Stimulation: Research and Clinical Applications begins by introducing readers to the foundational research and historical background of DBS, including developmental experimental models for movement and psychiatric disorders. The second section reviews various clinical applications, including numerous and in-depth case studies. The final section identifies the mechanisms of action behind DBS, including cellular, metabolic, and neurochemical mechanisms. Internationally contributed, this book is an essential guide for anyone in the field of DBS.
More details
Language
English
Place of publication
Oxford
United Kingdom
Publishing group
Elsevier Science & Technology
Target group
Professional and scholarly
Dimensions
Height: 229 mm
Width: 152 mm
Weight
760 gr
ISBN-13
978-0-323-99742-3 (9780323997423)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions

Yasin Temel | Abdelhamid Benazzouz | Ali Jahanshahi
The Neuroscience of Deep Brain Stimulation
Research and Clinical Applications
E-Book
02/2026
Elsevier
€175.00
Available for download
Persons
Yasin Temel is a Professor of Neurosurgery, Medical Center in Maastricht University, Maastricht, The Netherlands. Research Director Abdelhamid Benazzouz works in the Neurodegenerative Dis Institute, Bordeaux University, France. Experienced academic researcher with a demonstrated history of working in the field of Neuromodulation and Neurodegenerative disorders. Head of functional neurosurgery section at the department of neurosurgery. Skilled in Fundamental Neuromodulation research and academic teaching, Neuroanatomy, Animal Models, Electrophysiology, Behavior, Stereology and Microscopy. Co-founder and coordinator of Neuromodulation Master Specialization at Maastricht University.
Editor
Professor of Neurosurgery, Medical Center, Maastricht University, Maastricht, The Netherlands
Research Director, Neurodegenerative Dis Institute, Bordeaux University, France
Associate Professor at the Department of Neurosurgery, Maastricht University Medical Center, Maastricht, the Netherlands (0.8fte; permanent) Associate Professor at the Netherlands Institute for Neuroscience (NIN) (0.2fte; permanent)
Content
Part 1: Bench
1. The quest for a target and the beginning of the DBS-story
2. Early clinical application
3. Development of experimental models for movements disorders
4. Development of experimental models for psychiatric disorders
Part 2: Science behind the clinical application
5. Parkinson's disease
6. Dystonia
7. Essential tremor
8. Epilepsy
9. OCD
10. Tourette Syndrome
11. Depression
12. Alzheimer's disease
13. Other indications
Part 3: Mechanisms of action
14. Neurophysiological mechanisms
15. Cellular mechanisms
16. Metabolic mechanisms
17. Neurochemical mechanisms
18. Mechanisms investigated by imaging
Part 4. Future/perspectives
1. The quest for a target and the beginning of the DBS-story
2. Early clinical application
3. Development of experimental models for movements disorders
4. Development of experimental models for psychiatric disorders
Part 2: Science behind the clinical application
5. Parkinson's disease
6. Dystonia
7. Essential tremor
8. Epilepsy
9. OCD
10. Tourette Syndrome
11. Depression
12. Alzheimer's disease
13. Other indications
Part 3: Mechanisms of action
14. Neurophysiological mechanisms
15. Cellular mechanisms
16. Metabolic mechanisms
17. Neurochemical mechanisms
18. Mechanisms investigated by imaging
Part 4. Future/perspectives