Swine in the Laboratory
Surgery, Anesthesia, Imaging, and Experimental Techniques, Second Edition
2nd Edition
Published on 1. March 2007
Book
Hardback
496 pages
978-0-8493-9278-8 (ISBN)
Description
To diminish the learning curve associated with using swine as models, Swine in the Laboratory: Surgery, Anesthesia, Imaging, and Experimental Techniques, Second Edition provides practical technical information for the use of swine in biomedical research. The book focuses on models produced by surgical and other invasive procedures, supplying the basic principles for performing experiments with an organ or system of interest.
New to the Second Edition
Updated sections on anesthesia and perioperative care, including practical information for more complex models
Expansion of anatomic and physiologic details
Additional detail in the endoscopy section
Chapters on toxicology and radiobiology
Chapters that include angiographic, echocardiographic, CT, MRI, and PET imaging techniques with a corresponding DVD of the images
More tables of normal values on the most commonly used minipigs and domestic breeds
Beneficial for investigators, veterinarians, and technicians using swine for experimental and agricultural procedures, Swine in the Laboratory is certain to foster the appropriate, humane use of swine in biomedical research.
New to the Second Edition
Updated sections on anesthesia and perioperative care, including practical information for more complex models
Expansion of anatomic and physiologic details
Additional detail in the endoscopy section
Chapters on toxicology and radiobiology
Chapters that include angiographic, echocardiographic, CT, MRI, and PET imaging techniques with a corresponding DVD of the images
More tables of normal values on the most commonly used minipigs and domestic breeds
Beneficial for investigators, veterinarians, and technicians using swine for experimental and agricultural procedures, Swine in the Laboratory is certain to foster the appropriate, humane use of swine in biomedical research.
More details
Edition
2nd New edition
Language
English
Place of publication
Bosa Roca
United States
Publishing group
Taylor & Francis Inc
Target group
Professional and scholarly
Lab animal veterinarians, biomedical researchers, experimental surgical personnel, private veterinary practitioners, and veterinary and animal care technicians.
Edition type
New edition
Illustrations
277 s/w Photographien bzw. Rasterbilder, 48 s/w Tabellen, 381 s/w Abbildungen
277 Halftones, black and white; 48 Tables, black and white; 381 Illustrations, black and white
Dimensions
Height: 254 mm
Width: 178 mm
Weight
1066 gr
ISBN-13
978-0-8493-9278-8 (9780849392788)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
New editions
M. Michael Swindle | Alison C. Smith
Swine in the Laboratory
Surgery, Anesthesia, Imaging, and Experimental Techniques, Third Edition
Book
10/2015
3rd Edition
CRC Press
€225.50
Shipment within 15-20 days
Person
Medical University of South Carolina, Charleston, USA
Content
BIOLOGY, HANDLING, HUSBANDRY, AND ANATOMY
Introduction
Breed Selection
Biology
Taxonomy and Nomenclature
Reproduction
Growth and Development
Nutrition
Hematology
Behavior
Husbandry
Disease Prevention
Restraint and Handling
Administration of Medications and Injections
General Anatomy
Model Selection
References
ANESTHESIA, ANALGESIA, AND PERIOPERATIVE CARE
Introduction
Anesthetic Induction and Animal Prep Room Activities
Endotracheal Intubation
Special Perioperative Considerations
Malignant Hyperthermia
Paralytic Agents
Postoperative Monitoring
Preanesthetic Agents
Injectable Anesthetic Agents
Inhalant Anesthetics
Cardiopulmonary Bypass (CPB)
Regional Low-Flow Perfusion and Neural Protection
Analgesics
Commonly Recommended Protocols
General Physiological Effects of Anesthetics
Euthanasia
References
WOUND CLOSURE AND INTEGUMENT
General Principles and Surgical Preparation
Suture Selection for Wound Closure
Skin Flaps and Grafts
Wound-Healing Models
References
GASTROINTESTINAL PROCEDURES
Surgical Anatomy
General Principles of Abdominal Surgery
Postoperative Care
Gastronomy and Gastrostomy Techniques
Pyloroplasty
Enterotomy and Intestinal Fistulation
Intestinal Infusion Catheter Implantation
Intestinal Anastomosis
Intestinal Diversion or Intestinal Bypass
Colonic Anastomosis and Fistulation
Total Colectomy
Rectal Prolapse
Intestinal and Multivisceral Transplantation
Vagotomy
Intraperitoneal Sepsis, Septic Shock, and Hemorrhagic Shock
References
LIVER AND BILIARY SYSTEM
Surgical Anatomy and General Principles of Surgery
Cholecystectomy
Cannulation or Constriction of the Common Bile Duct
Partial Hepatectomy, Liver Biopsy, and Intrahepatic Cannulation
Liver Transplantation
Hepatic Xenoperfusion
References
PANCREAS AND SPLEEN
Surgical Anatomy and General Principles of Surgery
Pancreatectomy, Islet Cell Ablation, and Diabetes
Segmental Pancreatectomy, Pancreatic Transplant, and Islet Cell Isolation
Pancreatic Duct Ablation, Cannulation, and Pancreatitis
Splenectomy, Splenic Vascular Catheterization, and Splenic Transplantation
References
URINARY SYSTEM AND ADRENAL GLANDS
General Principles of Surgery and Surgical Anatomy
Nephrectomy
Partial Nephrectomy and Intrarenal Surgery
Renal Transplant
Cystotomy and Ureteral Diversion
Urinary Tract Obstruction, Reflux Nephropathy, and Hydronephrosis
Perineal Urethrostomy and Urinary Diversion
Preputial Diverticulum Ablation
Adrenalectomy
References
REPRODUCTIVE SYSTEM
General Principles of Surgery
Castration (Orchiectomy) and Vasectomy
Ovariohysterectomy, Hysterectomy, Ovariectomy, or Tubal Ligation
Cesarean Section (C-Section)
Fetal Surgery and Fetal Catheterization
Prolapse of the Reproductive Tract
Endometriosis
Pelvic Adhesions
Artifical Insemination and Embryo Transfer
Mammectomy
References
CARDIOTHORACIC AND VASCULAR SURGERY/CHRONIC INTRAVASCULAR CATHETERIZATION
General Principles of Cardiothoracic Surgery and Surgical Anatomy
Pulmonary System
Cardiovascular System
Miscellaneous Thoracic Procedures
HEAD AND NECK SURGERY/CENTRAL NERVOUS SYSTEM
General Principles of Surgery and Surgical Anatomy
Dental Procedures and Tusk Trimming
Maxillofacial and Craniotomy Procedures
Ocular Surgery
Pharyngostomy Tubes
Thyroidectomy
Parathyroidectomy
Hypophysectomy
Spinal Cord Ischemia and Hemorrhage
Stroke Models
Cerebrospinal Fluid (CSF) Collection and Epidural Injection
MUSCULOSKELETAL SYSTEM AND ORTHOPEDIC PROCEDURES
General Principles of Surgery and Surgical Anatomy
Amputation of a Digit and Hoof Trimming
Tendon and Ligament Repair
Tail Amputation
Hernia Repair
Surgical Approaches to Bones and Joints
Bone Marrow Aspiration
CARDIOVASCULAR CATHETERIZATION, ELECTROPHYSIOLOGY, AND IMAGING LABORATORY PROCEDURES
Introduction
Peripheral Vascular Access for Cardiovascular Catheters
Anesthetics and Adjunct Drugs
Hemodynamics
Angioplasty Balloon Techniques, Intravascular Device Implantations, and Restenosis
Atherosclerosis
Electrophysiology and Electrocardiography (ECG) and Telemetry
Pacemark Implantation and Endocardial Pacemaker Leads
Conduction System Ablation
Angiography
Echocardiography
ENDOSCOPIC, LAPAROSCOPIC, AND MINIMALLY INVASIVE SURGERY by M.M. Swindle and R.H. Hawes
Introduction
General Considerations
Anatomic Considerations for Flexible Endoscopic Research
Performing Endoscopy
Endoscopic Retrograde Cholangiopancreatography Research (ERCP)
Endoscopic Hemostasis (Gastrointestinal Bleeding)
Colonoscopy
Larynoscopy and Bronchoscopy
Training in Flexible Endoscopy
Laparoscopic, Celioscopic, and Thoracoscopic Surgery
Postoperative Care for Laparoscopic and Endoscopic Procedures
Natural Orifice Translumenal Endoscopic Surgery (NOTES)
Surgical Robotics
XENOTRANSPLANTATION AND TRANSGENIC TECHNOLOGIES
Introduction
Ethical Considerations
Immunologic and Physiological Considerations
Strategies for Development of Transgenic Animals
Regulatory Guidelines
Public Health Considerations
Management and Husbandry Strategies
Other Considerations
TOXICOLOGY by Ove Svendsen
Introduction
Domestic Pigs and Minipigs
Strains of Minipigs
Pharmacokinetics and Metabolism
Repeat Dose Toxicology
Reproductive Toxicology
Juvenile Studies
Regulatory Acceptance
Conclusions for Toxicological Models
Acknowledgments
RADIOBIOLOGY
IMAGING TECHNIQUES: CT, MRI, AND PET SCANNING by Aage Kristian Olsen, Dora Zeidler, Kasper Pedersen, Michael Sorensen, Svend Borup Jensen, and Ole Lajord Munk
Scanners
Anesthesia
Surgery
Monitoring
Scanning Procedures
Technical Information for DVD Images
OSSABAW ISLAND MINIATURE SWINE: CARDIOMETABOLIC SYNDROME ASSESSMENT by Michael Sturek, Mouhamad Alloosh, James Wenzel, James P. Byrd, Jason M. Edwards, Pamela G. Lloyd, Johnathan D. Tune, Keith L. March, Michael A. Miller, Eric A. Mokelke, and I. Lehr Brisbin, Jr.
Introduction
Characterization of the Model
Summary and Conclusions
Acknowledgments
APPENDIX
INDEX
References appear at the end of each chapter.
Introduction
Breed Selection
Biology
Taxonomy and Nomenclature
Reproduction
Growth and Development
Nutrition
Hematology
Behavior
Husbandry
Disease Prevention
Restraint and Handling
Administration of Medications and Injections
General Anatomy
Model Selection
References
ANESTHESIA, ANALGESIA, AND PERIOPERATIVE CARE
Introduction
Anesthetic Induction and Animal Prep Room Activities
Endotracheal Intubation
Special Perioperative Considerations
Malignant Hyperthermia
Paralytic Agents
Postoperative Monitoring
Preanesthetic Agents
Injectable Anesthetic Agents
Inhalant Anesthetics
Cardiopulmonary Bypass (CPB)
Regional Low-Flow Perfusion and Neural Protection
Analgesics
Commonly Recommended Protocols
General Physiological Effects of Anesthetics
Euthanasia
References
WOUND CLOSURE AND INTEGUMENT
General Principles and Surgical Preparation
Suture Selection for Wound Closure
Skin Flaps and Grafts
Wound-Healing Models
References
GASTROINTESTINAL PROCEDURES
Surgical Anatomy
General Principles of Abdominal Surgery
Postoperative Care
Gastronomy and Gastrostomy Techniques
Pyloroplasty
Enterotomy and Intestinal Fistulation
Intestinal Infusion Catheter Implantation
Intestinal Anastomosis
Intestinal Diversion or Intestinal Bypass
Colonic Anastomosis and Fistulation
Total Colectomy
Rectal Prolapse
Intestinal and Multivisceral Transplantation
Vagotomy
Intraperitoneal Sepsis, Septic Shock, and Hemorrhagic Shock
References
LIVER AND BILIARY SYSTEM
Surgical Anatomy and General Principles of Surgery
Cholecystectomy
Cannulation or Constriction of the Common Bile Duct
Partial Hepatectomy, Liver Biopsy, and Intrahepatic Cannulation
Liver Transplantation
Hepatic Xenoperfusion
References
PANCREAS AND SPLEEN
Surgical Anatomy and General Principles of Surgery
Pancreatectomy, Islet Cell Ablation, and Diabetes
Segmental Pancreatectomy, Pancreatic Transplant, and Islet Cell Isolation
Pancreatic Duct Ablation, Cannulation, and Pancreatitis
Splenectomy, Splenic Vascular Catheterization, and Splenic Transplantation
References
URINARY SYSTEM AND ADRENAL GLANDS
General Principles of Surgery and Surgical Anatomy
Nephrectomy
Partial Nephrectomy and Intrarenal Surgery
Renal Transplant
Cystotomy and Ureteral Diversion
Urinary Tract Obstruction, Reflux Nephropathy, and Hydronephrosis
Perineal Urethrostomy and Urinary Diversion
Preputial Diverticulum Ablation
Adrenalectomy
References
REPRODUCTIVE SYSTEM
General Principles of Surgery
Castration (Orchiectomy) and Vasectomy
Ovariohysterectomy, Hysterectomy, Ovariectomy, or Tubal Ligation
Cesarean Section (C-Section)
Fetal Surgery and Fetal Catheterization
Prolapse of the Reproductive Tract
Endometriosis
Pelvic Adhesions
Artifical Insemination and Embryo Transfer
Mammectomy
References
CARDIOTHORACIC AND VASCULAR SURGERY/CHRONIC INTRAVASCULAR CATHETERIZATION
General Principles of Cardiothoracic Surgery and Surgical Anatomy
Pulmonary System
Cardiovascular System
Miscellaneous Thoracic Procedures
HEAD AND NECK SURGERY/CENTRAL NERVOUS SYSTEM
General Principles of Surgery and Surgical Anatomy
Dental Procedures and Tusk Trimming
Maxillofacial and Craniotomy Procedures
Ocular Surgery
Pharyngostomy Tubes
Thyroidectomy
Parathyroidectomy
Hypophysectomy
Spinal Cord Ischemia and Hemorrhage
Stroke Models
Cerebrospinal Fluid (CSF) Collection and Epidural Injection
MUSCULOSKELETAL SYSTEM AND ORTHOPEDIC PROCEDURES
General Principles of Surgery and Surgical Anatomy
Amputation of a Digit and Hoof Trimming
Tendon and Ligament Repair
Tail Amputation
Hernia Repair
Surgical Approaches to Bones and Joints
Bone Marrow Aspiration
CARDIOVASCULAR CATHETERIZATION, ELECTROPHYSIOLOGY, AND IMAGING LABORATORY PROCEDURES
Introduction
Peripheral Vascular Access for Cardiovascular Catheters
Anesthetics and Adjunct Drugs
Hemodynamics
Angioplasty Balloon Techniques, Intravascular Device Implantations, and Restenosis
Atherosclerosis
Electrophysiology and Electrocardiography (ECG) and Telemetry
Pacemark Implantation and Endocardial Pacemaker Leads
Conduction System Ablation
Angiography
Echocardiography
ENDOSCOPIC, LAPAROSCOPIC, AND MINIMALLY INVASIVE SURGERY by M.M. Swindle and R.H. Hawes
Introduction
General Considerations
Anatomic Considerations for Flexible Endoscopic Research
Performing Endoscopy
Endoscopic Retrograde Cholangiopancreatography Research (ERCP)
Endoscopic Hemostasis (Gastrointestinal Bleeding)
Colonoscopy
Larynoscopy and Bronchoscopy
Training in Flexible Endoscopy
Laparoscopic, Celioscopic, and Thoracoscopic Surgery
Postoperative Care for Laparoscopic and Endoscopic Procedures
Natural Orifice Translumenal Endoscopic Surgery (NOTES)
Surgical Robotics
XENOTRANSPLANTATION AND TRANSGENIC TECHNOLOGIES
Introduction
Ethical Considerations
Immunologic and Physiological Considerations
Strategies for Development of Transgenic Animals
Regulatory Guidelines
Public Health Considerations
Management and Husbandry Strategies
Other Considerations
TOXICOLOGY by Ove Svendsen
Introduction
Domestic Pigs and Minipigs
Strains of Minipigs
Pharmacokinetics and Metabolism
Repeat Dose Toxicology
Reproductive Toxicology
Juvenile Studies
Regulatory Acceptance
Conclusions for Toxicological Models
Acknowledgments
RADIOBIOLOGY
IMAGING TECHNIQUES: CT, MRI, AND PET SCANNING by Aage Kristian Olsen, Dora Zeidler, Kasper Pedersen, Michael Sorensen, Svend Borup Jensen, and Ole Lajord Munk
Scanners
Anesthesia
Surgery
Monitoring
Scanning Procedures
Technical Information for DVD Images
OSSABAW ISLAND MINIATURE SWINE: CARDIOMETABOLIC SYNDROME ASSESSMENT by Michael Sturek, Mouhamad Alloosh, James Wenzel, James P. Byrd, Jason M. Edwards, Pamela G. Lloyd, Johnathan D. Tune, Keith L. March, Michael A. Miller, Eric A. Mokelke, and I. Lehr Brisbin, Jr.
Introduction
Characterization of the Model
Summary and Conclusions
Acknowledgments
APPENDIX
INDEX
References appear at the end of each chapter.