Polymeric Drug Delivery: Volume II: Particulate Drug Carriers
Published on 15. June 2006
Book
Hardback
394 pages
978-0-8412-3976-0 (ISBN)
Description
Polymeric Drug Delivery: Science & Application is designed to bridge the gap between industrial and academic researchers in drug delivery and the pharmaceutical industry because conferences focus one of these two aspects. The book covers three main topics of drug delivery: the use of particulate carriers to transport actives to specific sites within the body, the use of matrices to tailor release rates to drug specific needs, and technologies to engineer
drug particles in a way that will improve their bioavailability. Polymeric materials are being used in all three areas, as carriers, matrices, or part of the formulation of drug particles. Following an overview, this volume describes in twenty chapters the use of carriers such as liposomes, micelles, dendrimers,
emulsion droplets, nanoparticles, and yeast cells in the (targeted) delivery of poorly water-soluble drugs, small organic molecules, macromolecules such as proteins and nucleic acids, and metal ions for molecular imaging purposes. Different routes of application are described, including oral and transepithelial delivery.
drug particles in a way that will improve their bioavailability. Polymeric materials are being used in all three areas, as carriers, matrices, or part of the formulation of drug particles. Following an overview, this volume describes in twenty chapters the use of carriers such as liposomes, micelles, dendrimers,
emulsion droplets, nanoparticles, and yeast cells in the (targeted) delivery of poorly water-soluble drugs, small organic molecules, macromolecules such as proteins and nucleic acids, and metal ions for molecular imaging purposes. Different routes of application are described, including oral and transepithelial delivery.
More details
Series
Language
English
Place of publication
New York
United States
Target group
Professional and scholarly
Illustrations
45 halftones, 1 color & 196 line illus.
Dimensions
Height: 236 mm
Width: 157 mm
Thickness: 23 mm
Weight
602 gr
ISBN-13
978-0-8412-3976-0 (9780841239760)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Person
Content
Preface Overview 1: Sonke Svenson: Advances in Particulate Polymeric Drug Delivery Particulate Drug Carriers 2: Ronak Vakil, Anuj Kuldipkumar, David Andes, Yvonne Tan and Glen S. Kwon: Polymeric Micelles for the Delivery of Polyene Antibiotics 3: Masayuki Yokoyama: Polymeric Micelle Drug Carriers for Tumor Targeting 4: Cornelus F. van Nostrum, Dragana Neradovic, Osamu Soga, and Wim E. Hennink: Polymeric Micelles with Transient Stability: A Novel Drug Delivery Concept 5: Mira F. Francis, Mariella Piredda, Mariana Cristea and Francoise M. Winnik: Synthesis and Evaluation of Hydrophobically-Modified Polysaccharides as Oral Delivery Vehicles for Poorly-Water Soluble Drugs 6: Pingwah Tang, NaiFang Wang and Steven M. Dinh: Oral Delivery of Macromolecular Drugs 7: Jan A.A.M. Kamps, Henriette W.M. Morselt, Gerrit L. Scherphof and Gerben A. Koning: Immunoliposomes Directed Against Colon Adenocarcinoma Cells: Delivery of 5-Fluorodeoxyuridine to Colon Cancer Cells and Targeting to Liver Metastases 8: Debra T. Auguste, Robert K. Prud'homme, Patrick L. Ahl, Paul Meers and Joachim Kohn: Polymer-Protected Liposomes: Association of Hydrophobically-Modified PEG with Liposomes 9: Eric E. Simanek: Dendrimers Based on Melamine: Vehicles for Drug Delivery? 10: K. Bruce Thurmond II, John McEwan, Dan G. Moro, John R. Rice, Gregory Russell-Jones, John V. St. John, Paul Sood, Donald R. Stewart and David P. Nowotnik: Targeted and Non-Targeted Polymer Drug Delivery Systems 11: M. C. Morris, J. Depollier, S. Deshayes, F. Heitz and G. Divita: Peptide Carriers for Protein Transduction: How to Generate a Drug from your Favorite Protein 12: Jonathan B. Rothbard, Theodore C. Jessop, Paul A. Wender: Molecular Understanding of Cellular Uptake by Arginine-Rich Cell Penetrating Peptides 13: Darin Y. Furgeson and Sung Wan Kim: Recent Advances in Poly(ethyleneimine) Gene Carrier Design 14: Preeti Yadava, David Buethe and Jeffery A. Hughes: Nonviral Gene Delivery with Surfactants 15. Gene Delivery with Novel Poly(L-tartaramidoamine)s Yemin Liu, Laura Wenning, Matthew Lynch and Theresa M. Reineke 16: Edmund J. Niedzinski, Yadong Liu, and Eric Y. Sheu: Plasmid DNA Encapsulation Using an Improved Double Emulsion Process 17: Yoon Yeo and Kinam Park: A New Microencapsulation Technique Based on the Solvent Exchange Method 18: Kurt Breitenkamp, Denise Junge and Todd Emrick: Hollow Microcapsules for Drug Delivery by Self-Assembly and Crosslinking of Amphiphilic Graft Copolymers 19: G. Nelson, S.C. Duckham and M.E.D. Crothers: Microencapsulation in Yeast Cells and Applications in Drug Delivery 20: R. Keith Frank, Philip S. Athey, Gyongyi Gulyas, Garry E. Kiefer, Kenneth McMillan and Jaime Simon: Chelants for Delivery of Metal Ions 21: G. M. Lanza, P. M. Winter, M. S. Hughes, S. D. Caruthers, J. N. Marsh, A. M. Morawski, A. H. Schmieder, M. J. Scott, R. W. Fuhrhop, H. Zhang, G. Hu, E. K. Lacy, J. S. Allen and S. A. Wickline: Molecular Imaging and Therapy - New Paradigms for 21st Century Medicine