Drugs and Poisons in Humans
A Handbook of Practical Analysis
Published on 13. October 2010
Book
Paperback/Softback
XVIII, 672 pages
978-3-642-06087-8 (ISBN)
Description
It was with great pleasure that I accepted the invitation to write the foreword for Drugs and Poisons in Humans. A Handbook of Practical Analysis. Dr. Osamu Suzuki and Dr. Mikio Yashiki, two outstanding Japanese scientists, f rst published the Handbook in Japanese in 2002. Specialists throughout Japan contributed analytical methods for a wide variety of therapeutic and illicit drugs, pesticides, and natural toxins and alkaloids. In fact, rarely has such a wide spectrum of analytes and metabolites been addressed within a single reference manual. At the beginning of the book, general topics are addressed, including instructions on h- dling biological materials, measurement of drugs in alternative specimens, and guidance on resolving analytical problems that may occur. T ere are discussions of extraction modalities and detection methodologies and how to select these appropriately based on the physioche- cal characteristics of the drug. Analysis of specif c classes of drugs and relevant metabolites are covered in subsequent chapters. Clinical, analytical and forensic toxicology and clinical ch- istry laboratories will f nd the volume informative and useful. Toxicologists are of en faced with developing methods for new drugs and metabolites with little information available in the literature. T is book provides a great starting point for method development providing pro- dures that have been utilized in real life situations. In addition, toxicologists developing new methodologies may use this volume as a guide to selecting the most appropriate instrumen- tion to handle the breadth of their analytical workload.
More details
Edition
Softcover reprint of hardcover 1st ed. 2005
Language
English
Place of publication
Berlin
Germany
Publishing group
Springer Berlin
Target group
Professional and scholarly
Professional/practitioner
Illustrations
236 s/w Abbildungen
XVIII, 672 p. 236 illus.
Dimensions
Height: 23.5 cm
Width: 15.5 cm
Weight
1044 gr
ISBN-13
978-3-642-06087-8 (9783642060878)
DOI
10.1007/3-540-27579-7
Schweitzer Classification
Other editions
Additional editions
Book
05/2005
Springer
€320.99
Shipment within 10-15 days
Content
Chapters of general nature.- How to handle biological specimens.- Alternative specimens.- Pitfalls and cautions in analysis of drugs and poisons.- Pretreatments of human specimens.- Detection methods.- A computer system for diagnosis of causative drugs and poisons developed by the Japan Poison Information Center (Tokyo).- Practical use of the poison-net developed by the Japan Information Network (Hiroshima).- Problems in toxin analysis in emergency medicine.- Analysis of chemical warfare agents and their related compounds.- Chapters on specific toxins.- Carbon monoxide.- Hydrogen sulfide and its metabolite.- Cyanide.- Methanol and formic acid.- Ethanol.- Chloroform and dichloromethane.- Toluene, benzene, xylene and styrene.- Alkyl nitrites.- Components of gasoline and kerosene.- Amphetamines and their metabolites.- Cannabinoids and their metabolites.- Morphine and its analogues.- Cocaine and its metabolites.- Pentazocine.- Lysergic acid diethylamide (LSD).- 3,4-Methylenedioxyamphetamines.- Phencyclidine.- ?-Hydroxybutyric acid.- Phenothiazines.- Butyrophenones.- Tricyclic and tetracyclic antidepressants.- Benzodiazepines.- Bromisovalum.- Barbiturates.- Diphenylmethane antihistaminics.- Propionic acid derivative analgesic-antipyretics.- Acetaminophen (paracetamol).- Acetylsalicylic acid.- Antiepileptics.- Muscle relaxants.- ?-Blockers.- Local anaesthetics.- Salicylic acid.- ?-Lactam antibiotics.- Hypochlorite.- Benzalkonium chlorides.- Hair dyes.- Permethrin.- Boric acid.- Naphthalene.- p-Dichlorobenzene.- Ethylene glycol.- Aconite toxins.- Mushroom toxins.- Tetrodotoxin.- Methylxanthine derivatives.- Nicotine and cotinine.- Tropane alkaloids.- Oleander toxins.- Simultaneous analysis of pesticides by GC/MS.- Organophosphorus pesticides.- Glufosinate and glyphosate.-Carbamate pesticides.- Paraquat and diquat.- Cresol.- Diazine and triazine herbicides.- Coumarin rodenticides.- Sarin and its decomposition products.- VX and its decomposition products.- Sodium azide.- Arsenic compounds and other inorganic poisons.- Nitrate and nitrite compounds.- Methemoglobin.