Protein Adaptations and Signal Transduction: Volume 2
Published on 19. July 2001
Book
Hardback
312 pages
978-0-444-50759-4 (ISBN)
Description
This volume of Cell and Molecular Responses to Stress has two broad themes: an examination of selected protein adaptations that support stress tolerance and an analysis of signal transduction systems, those critical links between the perception of stress and the activation of the coordinated metabolic responses that ensure survival. Several chapters deal with adaptive responses to environmental cold temperature and highlight novel advances in mammalian hibernation, low temperature enzyme function, cold-shock and antifreeze proteins, and freezing survival. Other chapters stretch out to explore biochemical responses to diverse stresses including water stress, mechanical stress, nutrient availability, oxygen limitation and oxidative stress. The integral roles of protein kinases, transcription factors, oxygen free radicals, and oxygen-sensitive ion channels in the detection and mediation of stress responses are explored. The multiplicity of responses is emphasized and shows us the vast potential of cells and organisms to respond to innumerable stresses, great and small, and the regulatory principles and mechanisms that are used to allow life to adapt and endure in every environment on Earth.
Featuring:
A discussion of new advances in understanding protein adaptations that support organismal survival of stress.
State-of-the-art analysis of key components of cellular signal transduction pathways including protein kinases and calcium and the control, integration and action of signal transduction pathways in response to stresses including mechanical stress, nutrient availability, oxidative stress.
Featuring:
A discussion of new advances in understanding protein adaptations that support organismal survival of stress.
State-of-the-art analysis of key components of cellular signal transduction pathways including protein kinases and calcium and the control, integration and action of signal transduction pathways in response to stresses including mechanical stress, nutrient availability, oxidative stress.
Reviews / Votes
Mason Posner...I would strongly recommend this book to anyone interested in a current description of the molecular mechanisms that allow cells to react to stress. The chapters on kinase systems and their involvement in transduction pathways are important reading for any comparative biologist interested in stress. Any thorough analysis of stress response will need to integrate this new wealth of molecular information. Furthermore, the descriptions of how cells sense and response to diverse stresses can provide valuable insights to anyone thinking about stress response.
Journal of Experimental Biology
More details
Series
Language
English
Place of publication
Oxford
United Kingdom
Publishing group
Elsevier Science & Technology
Target group
Professional and scholarly
Weight
90 gr
ISBN-13
978-0-444-50759-4 (9780444507594)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
K. B. Storey | J. M. Storey
Protein Adaptations and Signal Transduction
E-Book
07/2001
Elsevier
€240.00
Available for download
Persons
Content
Preface.
List of contributors.
1. Signal transduction and gene expression in the regulation of natural freezing survival
(K.B. Storey, J.M. Storey).
2. Drosophila as a model organism for the transgenic expression of antifreeze proteins
(B.P. Duncker, D.E. Rancourt, M.G. Tyshenko, P.L. Davies, V.K. Walker).
3. Cold-adapted enzymes: an unachieved symphony (S. D'Amico, P. Claverie, T. Collins,
G. Feller, D. Georlette, E. Gratia, A. Hoyoux, M.-A. Meuwis, L. Zecchinon, C. Gerday ).
4. The role of cold-shock proteins in low-temperature adaptation (J.A. Wouters, F.M. Rombouts,
O.P. Kuipers, W.M. de Vos, T. Abee).
5. Hibernation: protein adaptations (A.M. Rubtsov).
6. Aquaporins and water stress (A.N. Van Hoek, Yan Huang, Pingke Fang).
7. Gene expression associated with muscle adaptation in response to physical signals
(G. Goldspink, Shi Yu Yang).
8. Early responses to mechanical stress: from signals at the cell surface to altered gene expression (M. Chiquet, M. Flueck).
9. Fasting and refeeding: models of changes in metabolic efficiency (S.P.J. Brooks).
10. Nutritional regulation of hepatic gene expression ( H.C. Towle).
11. The AMP-activated/SNF1 protein kinases: key players in the response of eukaryotic cells to
metabolic stress (D.G. Hardie).
12. Cellular regulation of protein kinase C (A.C. Newton, A. Toker).
13. Mitogen-activated protein kinases and stress (K.P. Hoeflich, J.R. Woodgett).
14. How to activate intrinsic stress resistance mechanisms to obtain therapeutic benefit (P.K. Ray,
T. Das, G. Sa).
15. Regulation of ion channel function and expression by hypoxia (C. Peers).
16. Ca2+
dynamics under oxidant stress in the cardiovascular system (T. Chakraborti, S. Das,
M. Mandal, A. Mandal, S. Chakraborti).
17. Role of NF-E2 related factors in oxidative stress (D. Bloom, S. Dhakshinamoorthy,
Wei Wang, C.M. Celli, A.K. Jaiswal).
18. Signal transduction cascades responsive to oxidative stress in the vasculature (Zheng-Gen Jin, B.C. Berk).
19. Oxidative stress signaling (H. Habelhah, Z. Ronai).
20. Antioxidant defenses and animal adaptation to oxygen availability during environmental stress (M. Hermes-Lima, J.M. Storey, K.B. Storey).
Index.
List of contributors.
1. Signal transduction and gene expression in the regulation of natural freezing survival
(K.B. Storey, J.M. Storey).
2. Drosophila as a model organism for the transgenic expression of antifreeze proteins
(B.P. Duncker, D.E. Rancourt, M.G. Tyshenko, P.L. Davies, V.K. Walker).
3. Cold-adapted enzymes: an unachieved symphony (S. D'Amico, P. Claverie, T. Collins,
G. Feller, D. Georlette, E. Gratia, A. Hoyoux, M.-A. Meuwis, L. Zecchinon, C. Gerday ).
4. The role of cold-shock proteins in low-temperature adaptation (J.A. Wouters, F.M. Rombouts,
O.P. Kuipers, W.M. de Vos, T. Abee).
5. Hibernation: protein adaptations (A.M. Rubtsov).
6. Aquaporins and water stress (A.N. Van Hoek, Yan Huang, Pingke Fang).
7. Gene expression associated with muscle adaptation in response to physical signals
(G. Goldspink, Shi Yu Yang).
8. Early responses to mechanical stress: from signals at the cell surface to altered gene expression (M. Chiquet, M. Flueck).
9. Fasting and refeeding: models of changes in metabolic efficiency (S.P.J. Brooks).
10. Nutritional regulation of hepatic gene expression ( H.C. Towle).
11. The AMP-activated/SNF1 protein kinases: key players in the response of eukaryotic cells to
metabolic stress (D.G. Hardie).
12. Cellular regulation of protein kinase C (A.C. Newton, A. Toker).
13. Mitogen-activated protein kinases and stress (K.P. Hoeflich, J.R. Woodgett).
14. How to activate intrinsic stress resistance mechanisms to obtain therapeutic benefit (P.K. Ray,
T. Das, G. Sa).
15. Regulation of ion channel function and expression by hypoxia (C. Peers).
16. Ca2+
dynamics under oxidant stress in the cardiovascular system (T. Chakraborti, S. Das,
M. Mandal, A. Mandal, S. Chakraborti).
17. Role of NF-E2 related factors in oxidative stress (D. Bloom, S. Dhakshinamoorthy,
Wei Wang, C.M. Celli, A.K. Jaiswal).
18. Signal transduction cascades responsive to oxidative stress in the vasculature (Zheng-Gen Jin, B.C. Berk).
19. Oxidative stress signaling (H. Habelhah, Z. Ronai).
20. Antioxidant defenses and animal adaptation to oxygen availability during environmental stress (M. Hermes-Lima, J.M. Storey, K.B. Storey).
Index.