Structural Studies of Protein-Nucleic Acid Interaction
The Sources of Sequence-Specific Binding
Published on 16. September 1993
Book
Paperback/Softback
98 pages
978-0-521-41489-0 (ISBN)
Description
The study of the interactions of proteins, whether they be enzymes, regulatory proteins or structural proteins, with nucleic acids is one of the most exciting areas of modern molecular biology. In this 1993 text, Professor Steitz reviews the wide-ranging research in structural studies of DNA-binding proteins and their complexes with DNA. The author clearly and concisely describes the uses of techniques in molecular genetics, DNA synthesis, protein crystallography and nuclear magnetic response. The book, by a now Nobel Prize-winning author, will continue to be enjoyed by anyone with an interest in this exciting area of research.
More details
Language
English
Place of publication
Cambridge
United Kingdom
Target group
College/higher education
Product notice
Paperback (trade)
Illustrations
Worked examples or Exercises
Dimensions
Height: 244 mm
Width: 170 mm
Thickness: 6 mm
Weight
186 gr
ISBN-13
978-0-521-41489-0 (9780521414890)
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Schweitzer Classification
Content
1. Introduction and overview; 2. Principles of sequence-specific nucleic-acid recognition; 3. DNA-binding structure motifs; 4. Similarities and differences in RNA and DNA recognition; 5. Sequence-specific DNA-binding proteins; 6. Sequence-independent DNA-binding proteins; 7. Sequence-specific RNA-binding proteins; 8. Conclusions and prospects; 9. Acknowledgements; 10. References; Index.