The Biological Basis of Radiotherapy
2nd Edition
Published in October 1989
Book
Paperback/Softback
334 pages
978-0-444-81099-1 (ISBN)
Description
Radiotherapy itself has expanded in scope, to encompass advanced technological developments in physics, new concepts in biology and increased complexity in patient management. In the past, radiotherapy was practised at a routine technical level, whereas now it is firmly based in internal medicine with a strong emphasis on clinical research. For the young clinician entering the specialty, the spectrum of possibilities is wide and it is particularly important that full advantage is taken of the opportunities to innovate and to maintain an awareness of developments in science that seem likely to impinge on the field. This excellent volume will certainly make an important contribution to this awareness, whilst refreshing senior clinicians in established practice.
More details
Edition
2nd Revised edition
Language
English
Place of publication
Oxford
United Kingdom
Publishing group
Elsevier Science & Technology
Target group
College/higher education
Professional and scholarly
Edition type
Revised edition
Dimensions
Height: 240 mm
Weight
830 gr
ISBN-13
978-0-444-81099-1 (9780444810991)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Classification
Content
Preface. List of Contributors. Chapter 1: Temporal stages of radiation action: free radical processes (G.E. Adams). Chapter 2: Mechanisms of repair of DNA damage induced by ionising radiation (P.E. Bryant). Chapter 3: The molecular basis of radiosensitivity (T.J. McMillan). Chapter 4: Survival of clonogenic cells: cell-survival curves (G.G. Steel). Chapter 5: Relation between cell survival and gross endpoints of tumour response and tissue failure (K.-R. Trott). Chapter 6: Cell proliferation kinetics in tumours (G.G. Steel). Chapter 7: Radiation damage to early-reacting normal tissues (J.H. Hendry). Chapter 8: Radiation effects on blood vessels: role in late normal-tissue damage (J.H. Hopewell, W. Calvo and H.S. Reinhold). Chapter 9: Physiological hypoxia and its influence on radiotherapy (J. Denekamp). Chapter 10: The clinical consequences of the oxygen effect (S. Dische). Chapter 11: Radiation sensitizers and bioreductive drugs (I.J. Stratford and G.E. Adams). Chapter 12: Radiobiology of human tumour cells (G.G. Steel). Chapter 13: Fractionation and therapeutic gain (J.F. Fowler). Chapter 14: Radiotherapy with multiple fractions per day (W. van den Bogaert, J.-C. Horiot and E. van der Schueren). Chapter 15: The dose-rate effect (G.G. Steel). Chapter 16: Clinical aspects of radiation dose rate (A. Horwich). Chapter 17: Heavy particles in radiotherapy (J.F. Fowler). Chapter 18: Combined radiotherapy-chemotherapy: principles (G.G. Steel). Chapter 19: Combined radiotherapy-chemotherapy in clinical practice (A. Horwich). Chapter 20: Cellular and tissue effects of hyperthermia and radiation (S.B. Field). Chapter 21: Prediction of tumour response to treatment (C.S. Parkins and A. Horwich). Subject index.