Description
In recent years, genomics research has taken great strides. In Genomics: Methods Express, a team of internationally-renowned researchers share the most up-to-date information in a field that has in recent years switched emphasis from gene identification to functional genomics and the characterization of genes and gene products. This volume approaches its complex subject with a broad perspective to supply its reader with a vital overview of genomics and its derivative fields, with a focus on pivotal issues such as data analysis. Expansive and current, Genomics: Methods Express is a comprehensive research guide that describes both the key new techniques and more established methods. Every chapter discusses the merits and limitations of the various approaches and then provides selected tried-and-tested protocols, as well as a plethora of good practical advice, for immediate use at the bench.
More details
Series
Language
English
Place of publication
Bloxham
United Kingdom
Target group
Professional and scholarly
Dimensions
Height: 234 mm
Width: 156 mm
Thickness: 19 mm
ISBN-13
978-1-904842-46-0 (9781904842460)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Classification
Content
1. High resolution analysis of genomic copy number changes Mario Hermsen, Hospital Universitario Central de Asturias; Jordy Coffa, Bauke Ylstra and Gerrit Meijer, all at VU University medical center, Amsterdam; Hans Morreau, Ronald van Eijk, Jan Oosting and Tom van Wezel, all at Leiden University Medical Center, Leiden 2. Identification of SNPs and small indels in humans and model organisms Raymond Miller, Washington University School of Medicine 3. Genotyping on archival tissue using high density SNP arrays T. van Wezel, Leiden University Medical Center 4. Genetic mapping of complex traits Nancy Saccone, Washington University School of Medicine 5. Transcriptional profiling using minute amounts of tissue Neil Winegarden, UHN Microarray Centre 6. Real-time quantitative RT-PCR for mRNA profiling Stephen Bustin, Royal London Hospital 7. Gene expression in mammalian cells F e9;lix Recillas-Targa, Universidad Nacional Aut f3;noma de M e9;xico 8. Proteome profiling David Friedman, Vanderbilt University Medical Center 9. Protein interaction mapping Chris Sanderson, University of Liverpool 10. Prediction of protein function Chua Hon Nian, Singapore 11. Elucidating gene function through use of genetically engineered mice Guoping Feng, Duke University Medical Center 12. Delivery systems for gene therapy Charlotte Lawson, Royal Veterinary College 13. Gene Therapy Strategies Ian Phillips, Keck Graduate Institute List of suppliers; Index