Methodology of Clinical Drug Trials
2nd Edition
Published on 18. January 1994
Book
Hardback
278 pages
978-3-8055-5856-3 (ISBN)
Description
'This is an excellent textbook on the subject and covers all aspects in a most pedagogic and pragmatic fashion, which enables the reader to learn, think and improve his/her decision making.' Int. Archives of Allergy and Applied Immunology
More details
Edition
2nd, revised edition
Language
English
Place of publication
Basel
Switzerland
Target group
Professional and scholarly
Edition type
New edition
Product notice
Trade binding
Illustrations
29
29 fig., 20 tab.; 29 Illustrations
Weight
850 gr
ISBN-13
978-3-8055-5856-3 (9783805558563)
Schweitzer Classification
Persons
Content
Principles of the controlled trial; selection of subjects; efficacy assessment; randomization; single-blind and double-blind trials; choice of the comparator - placebo or active drug?; dosage and therapeutic schema; experimental designs; subjects lost to follow-up; patient compliance and discontinuation of treatment; case report forms; multicentre trials; imperfect data analysis; confirmatory analysis of the principal evaluation criterion; interim analyses; exploratory analyses; "pragmatic trials" - decision methods; safety data; sample size; prudence and protection of participants; preparing a protocol.