Smith and Williams' Introduction to the Principles of Drug Design and Action, Fourth Edition
4th Edition
Published on 11. November 2004
Book
Paperback/Softback
978-0-415-28878-1 (ISBN)
Description
As knowledge of biological systems and the number of techniques available for exploring and visualizing their components has increased, it has become possible to design drugs specifically for a given target. Smith and Williams' Introduction to the Principles of Drug Design and Action, 4th Edition provides an introduction to the principles of rational drug design, including both novel and established approaches. This new edition adopts a 'from-bench-to-marketplace' approach, using real examples where possible. In addition to a comprehensive update of the previous edition, new advances in molecular techniques, biotechnological applications and computer-aided design have been added.
More details
Edition
4th ed.
Language
English
Place of publication
London
United Kingdom
Target group
Professional and scholarly
Edition type
New edition
Illustrations
30 Tables, black and white
ISBN-13
978-0-415-28878-1 (9780415288781)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Classification
Content
Processes of Drug Handling by the Body. The Design of Drug Delivery Systems. Experimental Pharmacokinetics: Design and Analysis. Intermolecular Forces and Molecular Modeling. Drug Chirality and its Pharmacological Consequences. Quantitative Structure - Activity Relationships and Drug Design. From Programme Sanction to Clinical Trials: A Partial View of the Quest for Arimidex (TM), a Potent, Selective Inhibitor of Aromatase. Pro-drugs. Design of Enzyme Inhibitors as Drugs. Stabilisation of Peptide Drugs by Chemical Manipulation. Combinational Chemistry: High-throughput Screening. Recombinant DNA Technology: Monoclonal Antibodies. Human Genome and its Implications to Drug Design: Pharmacogenetics and Pharmacogenomics. The Chemotherapy of Cancer. Neurotransmitters, Agonists and Antagonist. Design of Antimicrobial and Anti-fungal Agents. Bio-inorganic Chemistry and its Pharmaceutical Applications.