Multifaceted Role of IL-1 in Cancer and Inflammation
Published on 9. June 2023
Book
Paperback/Softback
192 pages
978-0-12-824273-5 (ISBN)
Description
Multifaceted Role of IL-1 in Cancer and Inflammation summarizes the existing literature and discusses future perspectives about the role of IL-1 in immune suppression, cancer progression, angiogenesis, and resistance to immunotherapies. The book presents mechanisms to overcome IL-1 mediated immune suppression in tumor microenvironment and covers topics on the source of IL-1 in the tumor microenvironment, IL-1 mediated downstream pathway, mechanism of IL-1 mediated immune suppression in cancer, and its effect on immunotherapy of cancer. Those topics help readers understand the effect of IL-1 on cancer immunopathology and immunotherapy, and provide them with broader concepts to develop therapies for IL-1 enrichment tumors.
This is a valuable source for cancer researchers, clinicians and other members of the biomedical field who wants to learn more about mechanisms to improve outcome of cancer immunotherapies.
This is a valuable source for cancer researchers, clinicians and other members of the biomedical field who wants to learn more about mechanisms to improve outcome of cancer immunotherapies.
More details
Language
English
Place of publication
San Diego
United States
Publishing group
Elsevier Science Publishing Co Inc
Target group
Professional and scholarly
Primary: Cancer researchers, oncologists, graduate students, medical scientists
Secondary: Pharmacologists, immunologists
Product notice
Paperback (trade)
Unsewn / adhesive bound
Illustrations
30 illustrations (15 in full color); Illustrations
Dimensions
Height: 152 mm
Width: 230 mm
Thickness: 15 mm
Weight
320 gr
ISBN-13
978-0-12-824273-5 (9780128242735)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Manisha Singh
Multifaceted Role of IL-1 in Cancer and Inflammation
E-Book
06/2023
Academic Press
€160.00
Available for download
Person
Manisha Singh, PhD, is a trained human and mouse immunologist and during the last 10 years, she has specialized in cancer immunology. The main focus of her work has been to increase the efficacy and understand the molecular mechanisms of various cancer immunotherapies. She is serving as the principal investigator on a 2-year grant ($545,486), having been funded by the US Department of Defense. Dr. Singh's current research is focused on understanding the role of inflammation in immune suppression and resistance to immunotherapy in cancer. Recently, she has submitted the NIH-R01 grant in which she proposed to study the role of IL-1? in immunotherapy induced resistance. She has published 24 peer-reviewed articles and many abstracts in prestigious journals such as Nature Communication, Journal of Immunology, and Journal of Clinical Investigator. Her work has been cited by several prestigious, peer-reviewed, international journals.
Content
1. Role of IL-1 gene polymorphisms in common solid cancers Ragini D. Singh, Sagar Dholariya, Anusmita Shekher, Avadhesh, Deepak Parchwani and Subash C. Gupta 2. The role of IL-1 in tumor growth and angiogenesis Kinjal Bhadresha, Pradeep K. Shukla and Pratibha Singh 3. Interleukin-1-mediated immune suppression and resistance to immunotherapy in cancer 4. Strategies to overcome interleukin-1-mediated immune suppression and resistance to immunotherapy in cancer Abhishek Puthenveetil, Shweta Dubey and Ankita Garg 5. Modulation of IL-1-mediated inflammation in cancer using a food-based approach: a preventive strategy Shubhi Singh, Smriti Gaur and Manisha Singh 6. IL-1-mediated inflammation in COVID-19 Preeti Jain, Baldeep Singh, Sadhna Aggarwal and Manisha Singh 7. Role of IL-1 in bacterial infections Aishwarya Rani and Devinder Toor