Bone Metastasis
Published on 20. January 2005
Book
Hardback
XIII, 344 pages
978-1-58829-403-6 (ISBN)
Description
A state-of-the-art review of the molecular underpinnings of bone-seeking cancers, current treatment approaches for them, and future therapeutic strategies. The authors illuminate the role of various autocrine, paracrine, and immunological factors involved in the progression and establishment of bone metastases, highlighting the physiological processes that lead to bone degradation, pain, angiogenesis, and dysregulation of bone turnover. They also discuss the various strategies that appear to have promise and are currently deployed in treatment or are at the experimental stage.
More details
Series
Edition
2005 ed.
Language
English
Place of publication
Totowa
United States
Target group
Professional and scholarly
Research
Illustrations
XIII, 344 p.
Dimensions
Height: 260 mm
Width: 183 mm
Thickness: 27 mm
Weight
964 gr
ISBN-13
978-1-58829-403-6 (9781588294036)
DOI
10.1385/1592598927
Schweitzer Classification
Other editions
Additional editions
Gurmit Singh | Shafaat A. Rabbani
Bone Metastasis
Book
11/2010
Humana Press Inc.
€117.69
Shipment within 15-20 days
E-Book
10/2007
1st Edition
Humana
€106.99
Available for download
Content
Fundamental Concepts.- Overview.- Parathyroid Hormone-Related Peptide and Malignancy.- Vitamin D and Vitamin D Analogs in Cancer Progression and Metastasis.- Role of TGF-? and IGF in Tumor Progression and Bone Metastases.- Biologic and Therapeutic Implications of Osteomimicry and Epithelial-Mesenchymal Transition in Prostate Cancer.- Roles of Immune-Cell-Derived Matrix Metalloproteinases in Tumor Growth and Metastasis.- Contribution of Osteopontin to the Development of Bone Metastasis.- Role of Interleukin-11 in Osteolytic Bone Metastasis.- Cell Adhesion Molecules in Tumor Metastasis.- PTHrP and Cancer.- Antithrombotics in Tumor Growth and Metastasis.- Therapeutic Strategies.- Challenges and Strategies in the Analysis of Multiple Events in Oncology.- Integrins.- Bone Metastasis and Pathological Fractures.- Role of Photodynamic Therapy for Bone Metastasis.- Docetaxel for Metastatic Cancer and Its Role in Combination Therapies for Advanced Prostate Cancer.- Use of Tetracyclines for Bone Metastases.- Role of Bisphosphonates in Skeletal Metastases.- Radiation Treatment of Bone Metastases.