
Hyaluronan Signaling and Turnover: Volume 123
Academic Press
Published on 30. July 2014
Book
Hardback
418 pages
978-0-12-800092-2 (ISBN)
Description
Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. This volume covers hyaluronan signaling and turnover.
More details
Series
Language
English
Place of publication
San Diego
United States
Publishing group
Elsevier Science Publishing Co Inc
Target group
Professional and scholarly
Dimensions
Height: 229 mm
Width: 152 mm
Weight
840 gr
ISBN-13
978-0-12-800092-2 (9780128000922)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions

Melanie Simpson | Paraskevi Heldin
Hyaluronan Signaling and Turnover
E-Book
07/2014
Academic Press
€129.00
Available for download
Persons
Paraskevi Heldin, Ph.D., received her B.Sci. exam (Chemistry/Biochemistry Mathematics), Uppsala University in 1979 and her Ph.D., in Medical and Physiological Chemistry for studies on regulatory phosphorylation of proteins, Faculty of Medicine, Uppsala University, in 1987. After dissertation she changed research area and focused on the biology of hyaluronan under the supervision of Professor T.C. Laurent, Uppsala University. She worked at Department of Medical and Physiological Chemistry during 1987- 2000, and was awarded Docent appointment in Medical and Physiological Chemistry and Scientist Position from The Goeran Gustafsson Foundation. Since 2001, she is Adjunct Associate Professor at the Department of Medical Biochemistry and Microbiology, and Associate Investigator and Head of the Matrix Biology Group in Ludwig Institute for Cancer Research, Uppsala, Sweden. Year 2013, she has appointed Adjunct Professor at the Department of Medical Biochemistry and Microbiology, Uppsala Unversity, Sweden. Dr Heldin's interests are focused on understanding the mechanisms of how hyaluronan-CD44 complexes interact with the receptors for the growth factors PDGF and TGF? for modulation of the proliferative and invasive behavior of malignant cells.
Author
Department of Biochemistry, University of Nebraska, USA
Ludwig Institute for Cancer Research Ltd, Sweden
Content
1.Emerging Roles for Hyaluronidase in Cancer Metastasis and Therapy2.Targeting Hyaluronic Acid Family for Cancer Chemoprevention & Therapy3.Aberrant Post-Transcriptional Processing of Hyaluronan Synthase 1 in Malignant Transformation and Tumor Progression 4.Hyaluronan Synthases Post-Translational Regulation in Cancer5.Hyaluronon-Coated Extracellular Vesicles - A Novel Link Between Hyaluronan and Cancer6.Hyaluronan in the Healthy and Malignant Hematopoietic Microenvironment7.Hyaluronan Regulation of Endothelial Barrier Function in Cancer8.HAS2 and CD44 in Breast Tumorigenesis9.CD44 is a Multidomain Signaling Platform that Integrates Extracellular Matrix Cues with Growth Factor and Cytokine Signals10.Hyaluronan-CD44 Interaction Promotes Oncogenic Signaling, MicroRNA Functions, Chemoresistance and Radiation Resistance in Cancer Stem Cells Leading to Tumor Progression11.Advances and Advantages of Nanomedicine in the Pharmacological Targeting of Hyaluronan-CD44 Interactions and Signaling in Cancer12.Hyaluronan / RHAMM Interactions in Mesenchymal Tumor Pathogenesis: Role of Growth Factors13.CD147: Regulator of Hyaluronan Signaling in Invasiveness and Chemoresistance