Cholinergic Mechanisms

HEILBRONN LECTURE
In Memoriam: Edith Heilbronn, V.P. Whittaker
NICOTINIC RECEPTORS: STRUCTURE
Nicotinic Acetylcholine Receptors: Probing Functionally Significant Structural Changes with Site-Directed Reactions, A. Karlin
The Binding Site for -Bungarotoxin in the Acetylcholine Receptor: From Synthetic Peptides to Solution and Crystal Structure, S. Fuchs, R. Kasher, M. Balass, T. Scherf, M. Harel, M. Fridkin, J.L. Sussman, and E. Katchalski-Katzir
Pharmacological and Structural Characterization of the Interaction of Snake Toxins with Nicotinic Acetylcholine Receptors, D. Servent, C. Fruchart-Gaillard, and A. Menez
Structure and Dynamics of Acetylcholine Receptor and its Lipid Microenvironment: From Molecule to Cell, S. Antollini, J. Baier, M. Blanton, I. Bonini, B. De los Santos, M.C. Gallegos, I. Garbus, M.F. Pediconi, M. Prieto, A.M. Roccamo, J. Wenz, and F.J. Barrantes
Site-Directed Reactive Probes for Structural and Functional Investigation of Cholinergic Proteins, C. Che, T. Grutter, A. Mourot, F. Hibert, and M. Goeldner
The Mechanism for Acetylcholine Receptor Inhibition by -Neurotoxins and Species-Specific Resistance to -Bungarotoxin Revealed by NMR, A.O. Samson, T. Scherf, M. Eisenstein, J.H. Chill, and J. Anglister

MUSCARINIC RECEPTORS: STRUCTURE
Structure and Activation of Muscarinic Acetylcholine Receptors, E.C. Hulme, Z.L. Lu, J.W. Saldanha, and M.S. Bee
Generation and Analysis of Muscarinic Acetylcholine Receptor Knockout Mice A. Duttaroy, M. Yamada, J. Gomeza, W. Zhang, T. Miyakawa, R. Makita, F.P. Bymaster, C.C. Felder, C.-X. Deng, and J. Wess
Roles of External loops of Muscarinic Receptors in Interactions between N-Methylscopolamine and Allosteric Modulators, S. Tuc?ek, A. Krejc?i, M. Lysikova, J. Jakubik, and V. Dolez?al

COUTEAUX LECTURE
Rene Couteaux (1909-1999) and his Presynaptic Active Zone, S. Tsuji
Rene Couteaux Lecture: Ligand Recognition in the Cholinergic Nervous System Analysed by Structural Templates and Protein Dynamics, P. Taylor

PRESYNAPTIC MECHANISMS
Neuronal Calcium Dynamics: One Message with Many Meanings, A. Fendyur, I. Kaiserman, and R. Rahamimoff
Acetylcholine- and Glutamate-Mediated Transmission: One Mediatophore with Different Specificities, or Several Mediatophores? M. Israel and Y. Dunant
The Ca-Voltage Hypothesis for Neurotransmitter Release - Current Status, H. Parnas and I. Parnas

STRUCTURAL AND REGULATORY ASPECTS OF THE CHOLINERGIC SYNAPSE
The Role of P2Y1 Nucleotide Receptors in the Formation and Maintenance of the Skeletal Neuromuscular Junctions, K.W.K. Tsim, R.C.Y. Choi, N.L. Siow, A.W.M. Cheng, K.K.Y. Ling, E.K.K. Tung, L.W. Kong, and E.A. Barnard
Control of Expression of Nicotinic Receptor and Acetylcholinesterase in the Developing Neuromuscular Junction in the Human Muscle, Z. Grubic, K. Mis, M. Jevsek, M. Brank, M.P King, A.F. Miranda, J. Brecelj, and T. Mars
The Molecular Neurobiology of Acetylcholinesterase Variants: From Stressful Insults to Antisense Intervention, H. Soreq, E. Meshorer, O. Cohen, R. Yirmiya, D. Ginzberg, and D. Glick
Transcriptional Control of the Cholinergic Gene Locus: A Mosaic model for Regulation of the Cholinergic Phenotype, B. Schuetz, M.K.-H. Schaefer, E. Weihe, and L.E. Eiden
Regulation of Cholinergic Gene Expression by NRSF/REST, L.B. Hersh and M. Shimojo
Unveiling the Molecular Events Leading to a Neurotransmitter Phenotype Switch in Developing Neurons, Y. Bogoch, Y. Bledi, S. Tayar, and M. Linial

MIRIAM SALPETER LECTURE
Miriam M. Salpeter (Mika) - Biographical Notes, L. Anglister
Chemical Kinetics Parameters and Receptor Degradation Rates at the Neuromuscular Junction, E.E. Salpeter

STRUCTURAL AND FUNCTIONAL STUDIES ON CHOLINESTERASES
Processing and Anchoring of Cholinesterases in Muscle and Brain, J. Massoulie and S. Bon
X-Ray Structures of Native and Soman-Aged Human Butyrylcholinesterase: New Insights into the Catalytic Mechanism of Cholinesterases, F. Nachon, Y. Nicolet, P. Masson, O, Lockridge and J.-C. Fontecilla-Camps
Intrinsic Tryptophan Fluorescence of Cholinesterases: Direct, Nonperturbing Monitoring of Enzyme-Ligand Interactions, Z. Radic', E. Kim, and P. Taylor
Surprising Findings from the Functional Analysis of Human Acetylcholinesterase Adducts of Alzheimer's Disease Drugs, A. Ordentlich, D. Barak, N. Ariel, C. Kronman, D. Kaplan, B. Velan, and A. Shafferman
Crystal Structure of the Tetramerization Domain of Acetylcholinesterase at 2.3 A Resolution, M. Harel, H. Dvir, S. Bon, W.Q. Liu, C. Garbay, J.L. Sussman, J. Massoulie, and I. Silman

THE CHOLINERGIC SYSTEM IN INVERTEBRATES
Structure and Expression of the Four Acetylcholinesterase Genes in the Nematode Caenorhabditis elegans, D. Combes, Y. Fedon, J.-P. Toutant, and M. Arpagaus
Regulation of Cholinergic Neurotransmitter Phenotypes, P.M. Salvaterra, M.-H. Lee, and S. Song
Molecular and Functional Diversity in the Nicotinic Acetylcholine Receptor Gene Families of Caenorhabditis elegans and Drosophila melanogaster, D.B. Sattelle, E. Culetto, and A.K. Jones
Genetic Dissection of an Acetylcholine Receptor Involved in Neuronal Degeneration, M. Treinin, S. Halevi, and L. Yassin

AUTOIMMUNE DISEASES RELATED TO THE CHOLINERGIC SYNAPSE
Congenital Myasthenic Syndromes: Multiple Molecular Targets at the Neuromuscular Junction, A.G. Engel, K. Ohno, and S.M. Sine
Antibodies to Acetylcholine Receptors and MuSK in Myasthenia Gravis and Related Disorders, A. Vincent, J. McConville, P. Plested, T. Tang, L. Jacobson, A. Polizzi, S. Riemersma, C. Newland, D. Beeson, J. Newsom-Davis, and W. Hoch
Muscarinic Receptor Autoantibodies in Sjoegren's Syndrome, M. Rischmueller
Immunotherapy of Myasthenia gravis: Antigen-Specific Mucosal Tolerance and Antagonists of Key Cytokines and Co-Stimulatory Factors, M.C. Souroujon, T. Feferman, P.K. Maiti, S.-H. Im, L. Raveh, and S. Fuchs

TOXICOLOGY AND PHARMACOLOGY OF CHOLINESTERASE INHIBITORS
A Complex Array of Post-Translation Modifications Determines the Circulatory Longevity of Acetylcholinesterase in a Hierarchical Manner, A. Shafferman, T. Chitlaru, A. Ordentlich, B. Velan, and C. Kronman
Therapeutic Efficacy in Organophosphate Poisoning by Inhibiting Central Release of Acetylcholine, T.J.H. Bueters, B. Groen, P.K. Harrison, J.E.H. Tattersall, A.P. IJzerman, M. Danhof, and H.P.M. van Helden
Polyurethane Immobilized Enzymes: Organophosphate-Sensing Matrixes, R.K. Gordon, A.T. Gunduz, B.P. Doctor, and T. Cronin
Sex Differences in the Actions of Cholinesterase Inhibitors, M. Weinstock and R.-H. Wang
Bifunctional Compounds Eliciting Both Anti-Inflammatory and Cholinergic Activity as Potential Drugs for CNS Disorders, G. Amitai, R. Adani, I. Rabinovitz, E. Beit-Yanai, E. Shohami, G. Sod-Moriah, and H. Meshulam

BRZIN LECTURE
In Memoriam: Miroslav Brzin (13 April 1923-8 August 1999), E. Reiner
Acetylcholinesterase Regulation in Skeletal Muscles, N. C? rne-Finderle, P. Pregelj, and J. Sketelj

PHARMACOLOGY OF NICOTINIC AND MUSCARINIC RECEPTORS IN THE CNS
Nicotinic Receptor Modulation: Implications for Treatment of Alzheimer's Disease and Other Neurological Disorders, E.X. Albuquerque, E.F.R. Pereira, M. Samochocki, M. Alkondon, C. Ullmer, and A. Maelicke
Common Structural and Pharmacological Properties of Serotonin 5-HT3 Receptors and 7 Nicotinic Acetylcholine Receptors, R. Zwart, M. Bodkin, L.M. Broad, G. De Filippi, P.J. Craig, T. Baldwinson, G. Benedetti, C. Felthouse, G.I. McPhie, K.H. Pearson, and E. Sher
Autonomic Function of Neuronal Nicotinic Acetylcholine Receptor Subunits 5, 2 and 4: Study in Knockout Mice, N. Wang, A. Orr-Urtreger, and A.D. Korczyn
Preclinical Studies of Galantamine Using a Form of Associative Learning Severely Impaired in Alzheimer's Disease, D.S. Woodruff-Pak
New Evidence for the Involvement of Muscarinic Cholinergic Receptors in Psychoses, F.P. Bymaster, D.L. McKinzie, and C.C. Felder

CHOLINERGIC-AMYLOID CROSS-TALK
Beta-Amyloids, Tau Hyperphosphorylation, and Cognition are Beneficially Affected by M1 Muscarinic Agonists: Perspectives in Alzheimer's Disease Treatment, A. Fisher, Z. Pittel, R. Haring, N. Bons, N. Bar-Ner, H. Sonego, N. Natan, I. Marcovitch, and R. Brandeis
PKC and MAP Kinase-Dependent Processing of Amyloid Precursor Protein (APP) by Neuroprotective Propargylamine Cholinesterase Inhibitors Derived from Rasagiline and Nonsteroidal Anti-Inflammatory Drugs, M.B.H. Youdim, T. Amit, Y. Avramovich, O. Bar-Am, M. Weinstock, and M. Yogev-Falach
Neurodegenerative Processes in Alzheimer's Disease: Role of A -AChE Complexes and Wnt Signaling, N.C. Inestrosa, G. De Ferrari, C. Opazo, and A. Alvarez
The Effects of ApoE3 and apoE4 on Lipid Synthesis and Uptake, L. Berger, A. Devir, M. Efrati, and D.M. Michaelson

CHOLINERGIC PATHWAYS AND REGULATION IN THE CNS
Cholinergic Cortical Terminations Establish Classical Synapses and Undergo Age-Related Atrophy, A.C. Cuello
Development of Cholinergic Projections to Cortex: Possible Role of Neurotrophins in Target Selection, R.T. Robertson and J. Yu
Activation of the Cholinergic System During Cognitive Processes, M.G. Giovannini, M.B. Passani, and G. Pepeu
How is the Brain Protected against Excess Choline Concentrations? K. Loeffelholz and J. Klein
Conditions for a Precursor Control of Acetylcholine Release in Mouse Hippocampus, J. Klein, M.-L. Buchholzer, S. Kopf, and K. Loeffelholz
Cholinergic Neurons in Culture: Regulation of Structure and Functions, M. Segal and V. Greenberger

CLINICAL STUDIES ON ALZHEIMER PATIENTS
Cholinesterase Inhibitors Stabilize Cognitive Decline in Alzheimer Patients Through -Amyloid Metabolism Interaction, E. Giacobini
Measuring Cerebral Acetylcholine Esterase Activity in Alzheimer Dementia by PET Functional Parametric Imaging, K. Herholz, G. Zuendorf, B. Bauer, S. Weisenbach, and W.-D. Heiss
Persistent Blood-Brain Barrier Disruption in Humans: A Window for Neurodegenerative Diseases, E. Avivi, O. Tomkins, A. Korn, L. Pavlovsky, I. Shelef, and A. Friedman
The Cholinergic System and Cognitive and Noncognitive behavioral Dysfunction in Alzheimer's Disease, P.T. Francis and S.L. Minger

CLOSING SESSION
Conclusions and Comments: XI ISCM, A.G. Karczmar

POSTER PRESENTATIONS
A Single Amino Acid Substitution Found in Pirimicarb-Insensitive Acetylcholinesterase of the Peach-Potato Aphid, Myzus persicae (Sulz.), M.C. Andrews, C.G. Bass, M.S. Williamson, L.M. Field, A. Callaghan, and G.D. Moores
The Effect of Diet Restriction, Separation Stress, Activity Wheel, and Tyrosine Administration on Cognitive Function and the Cholinergic System in Mice, Y. Avraham, S. Hao, and E.M. Berry
Nicotine Induces Glutamate Release from Hippocampal Mossy Fiber Synaptosomes, V. Bancila, A. Bloc, and Y. Dunant
Human Panic Disorder and the Cholinergic System: Further Considerations on a Gene-Environment Interaction Model, M. Battaglia, A. Ogliari, F. Villa, L. Ferini-Strambi, and C. Maffei
A Zebrafish Mutant as a Model for an Acetylcholinesterase-Deficient Vertebrate, M. Behra, X. Cousin, C. Bertrand, J.-L. Vonesch, A. Chatonnet, and U. Straehle
The Agonist Biphasic Dose-Response Curve of Human 4 2 Nicotinic Acetylcholine Receptors is Influenced by Ca2+ ions and Phosphokinase C, I. Bermudez and L.M. Houlihan
Dramatic Depletion of Cell Surface Muscarinic Receptor Due to Limited Delivery from Intracytoplasmic Stores in Neurons of Acetylcholinesterase-Deficient Mice, V. Bernard, C. Brana, I. Liste, O. Lockridge, and B. Bloch
Role of Spontaneous Mutations of Neuronal Nicotinic Acetylcholine Receptors in ADNFLE, D. Bertrand, I. Favre, H. Phillips, S. Bertrand, S.F. Berkovic, and J. Mulley
Quantal Acetylcholine Release through Mediatophore Proteolipid, A. Bloc, J. Falk-Vairant, M. Malo, M. Israel, and Y. Dunant
Superior Cervical Ganglia of the Cat: Cholinergic Mechanisms and their Relevance to Normal Mediation of Coordinate Respiratory and Deglutition Cervical Organs, B. Blum and J. Israeli
Cholinergic Modulation of Chemotaxis in Human Melanoma Cells, A. Boss, M. Oppitz, G. Lippert, and U. Drews
Some Considerations Concerning the Molecular Mechanism of Cholinesterase Catalysis, N.B. Brovtsyna, E.V. Rozengart, A.A. Suvorov, and S.N. Moralev
Muscarinic Neuromodulation in the Hippocampus and Parahippocampal Region, R.O. Browne, L. Pavlovsky, and A. Friedman
In Vivo Cholinergic Effects in the Rat of Head-to-Tail 3-Alkylpiridinium Polymers Isolated from the Marine Sponge Reniera sarai, M. Bunc, J. Rozman, M. Brvar, A. Vidmar, J.S. S?uput, and D. S?uput
Candoxin: A New Snake Toxin Specific for the 7 Nicotinic Acetylcholine Receptor, E. Charpantier, S. Nirthanan, P. Gopalakrishnakone, M.C.E. Gwee, H.E. Khoo, L.S. Cheah, R. Manjunatha Kini, and D. Bertrand
Effect of Post-Translation Modifications of Human Acetylcholinesterase on its Circulatory Residence, T. Chitlaru, C. Kronman, S. Lazar, N. Seliger, B. Velan, and A. Shafferman
NF B Regulates the Promoter Activity of Human Acetylcholinesterase in Muscle, R.C.Y. Choi, N.L. Siow, A.W.M. Cheng, L.W. Kong, X. Zhang, D.C.C. Wan, and K.W.K. Tsim
Generation of Pharmacokinetically Improved Recombinant Human Acetylcholinesterase by Polyethylene Glycol Modification, O. Cohen, C. Kronman, T. Chitlaru, A. Ordentlich, B. Velan, and A. Shafferman
Interaction of Recombinant Soluble Neuroligin-1 with Neurexin-1-ss, D. Comoletti, R. Flynn, L. Jennings, R. Hoffman, P. Marchot, Y. Bourne, T. Suedhof, and P. Taylor
A Calcium-Proton Antiport in Presynaptic Nerve Terminals, M. Cordeiro, V. Bancila, A. Bloc, P. Goncalves, and Y. Dunant
Buprofezin and Novaluron Inhibit Acetylcholinesterase Activity in B-biotype Bemisia Tabaci, E.L.A. Cottage and R.V. Gunning
A Peptide from the C-Terminal Oligomerization Domain of Human Synaptic (T-form) Acetylcholinesterase Forms Classical Amyloid Fibrils, M.G. Cottingham, M.S. Hollinshead, and D.J.T. Vaux
Identification of Species Differences in the Pharmacology of the -7 Nicotinic Receptor Using the Antagonist Radioligand [3H]-Methyllycaconitine, N. Crawford, K. Finlayson, J. Sharkey, and J.S. Kelly
Combination Donepezil and Dihydroepiandrosterone Therapy for Post-Stroke Rehabilitation, J.W. Crayton, L.M. Konopka, and A. Karczmar
E. coli-expressed Extracellular Domain of Rat 7 Nicotinic Acetylcholine Receptor: Physicochemical and Binding Properties, N.I. Dergousova, E.A. Azeeva, E.V. Kryukova, E.D. Shibanova, I.E. Kasheverov, A.S. Korotina, Y.N. Utkin, and V.I. Tsetlin
NO-Dependent and NO-Independent cGMP Synthesis in Cortical Cholinergic Neurons of the Rat Brain, J. de Vente, W.C.G. van Staveren, M. Markerink-van Ittersum, and H.W.M. Steinbusch
Calcium Mobilization and Cellular Contraction of Embryonic Lens Vesicle and Neural Tube on Muscarinic Cholinergic Stimulation, U. Drews, M. Oppitz, and G. Schriek
Phenotype of the Adult Acetylcholinesterase-Deficient Mouse: Evidence for a Role of Acetylcholinesterase in Development, E.G. Duysen, J.A. Stribley, D.L. Fry, S.H. Hinrichs, and O. Lockridge
MALDI-TOF/MS Analysis of Tabun-Acetylcholinesterase Conjugate: A Tool for Resolution of the 'Aging' Pathway, E. Elhanany, A. Ordentlich, O. Dgany, D. Kaplan, Y. Segall, R. Barak, B.h Velan, and A. Shafferman
Transgenic Manipulations of Neuromuscular Junction Maintenance, T. Evron and H. Soreq
Tetanic Fade is Revealed by Blocking Presynaptic Nicotinic Receptors Containing 3 2 Subunits after Reducing the Safety Factor of Neuromuscular Transmission, M. Faria, L. Oliveira, M.A. Timoteo, M.G.B. Lobo, and P. Correia-de-Sa
Functional Expression and Stoichiometry of the Novel Human 9 10 Heteromeric Nicotinic Acetylcholine Receptor, C. Grantham, I. Vandenberk, D. Nieuwstraten, P. Groot-Kormelink, L. Van der Helm, J. Yon, A. Kremer, P. Van der Spek, S. Masure, W. Luyten, and J. Andrews
Piperonyl Butoxide: A Specific Inhibitor of Insecticide-Resistant Acetylcholinesterase, R.V. Gunning
The Interaction of 2-Aminoperimidine with Cholinesterases, D. Gur, D. Segal, and Y. Shalitin
Influence of Water on the Function of Acetylcholinesterase, R. Henchman, K. Tai, T. Shen, and J.A. McCammon
-Conotoxins PnIA and [A10L]PnIA Stabilize Different States of the Chick Neuronal 7 Acetylcholine Receptor, R.C. Hogg, S. Bertrand, P.F. Alewood, D.J. Adams, and D.C. Bertrand
Acetylcholinesterase Knockout Mice have Increased Sensitivity to Scopolamine and Atropine, A. Hrabovska, E. Duysen and O. Lockridge
Investigating the Diversity of Acetylcholinesterase in Insect Species, N. Javed, M. Williamson, R. Viner, T. Lewis, and G. Moores
Origin of Acetylcholinesterase in the in vitro Formed Neuromuscular Junction, M. Jevsek, T. Mars, K. Mis, and Z. Grubic
Nicotinic 4 Receptor-Mediated Acetylcholine Release from Rat Interpenduncular Nucleus, F.A. Jones, L.R. Johnson, and I.A. Pullar
Attempts to Engineer an Enzyme Mimic of Butyrylcholinesterase by Substitution of the Six Divergent Aromatic amino Acids in the Active Center of Acetylcholinesterase, D. Kaplan, A. Ordentlich, D. Barak, N. Ariel, C. Kronman, B. Velan, and A. Shafferman
Mapping the Acetylcholine-Binding Sites of Torpedo Nicotinic Receptor Using Photoaffinity Labeling: Past, Present, and Future, F. Kotzyba-Hibert, A. Mourot, T. Grutter, and M. Goeldner
Phosphonylation of Acetylcholinesterase and the Propensity for Reactivation Analysed by Chirality and Mutagenesis, Z. Kovarik, Z. Radic', H.A. Berman, and P. Taylor
Some Basic Rules Governing Oligosaccharide-Dependent Circulatory Residence of Glycoproteins are Revealed by MALDI-TOF Mapping of the Multiple N N-Glycans Associated with Recombinant Bovine Acetylcholinesterase, C. Kronman, T. Chitlaru, N. Seliger, S. Lazar, A. Lazar, L. Zilberstein, B. Velan, and A. Shafferman
Identification and Characterization of a Diverse Family of Neurotoxin-Like Peptides from the South American Coral Snake, T. Kubo, G. Baptista, X. Yang, S. Kobayashi, M. Takeda, A. Prieto-Da-Silva, and T. Yamane
Muscarinic Acetylcholine Receptors are Down-Regulated in Acetylcholinesterase Knockout Mice, B. Li, E.G. Duysen, and O. Lockridge
Altered Activity of Cholinergic Enzymes in Muscles and Brain of the Obese-Diabetic (ob/ob) Mouse, M.C. Lintern, L. Cooke, H. Scriven, C.J. Bailey, and M.E. Smith
Two Possible Orientations of the HI-6 Molecule in the Reactivation of Organophosphate-Inhibited Acetylcholinesterase, C. Luo, H. Leader, Z. Radic', D.M. Maxwell, P. Taylor, B.P. Doctor, and A. Saxena
Exploring the Acetylcholinesterase Gorge with Bis-Galanthamine Derivatives, E. Luttmann, E. Linnemann, and G. Fels
Formation of Neuromuscular Junctions in Co-Cultures of Human Muscle and Rat Embryonic Spinal Cord is Accompanied by Differentiation of Neuronal and Glial Cells, T. Mars, K.J. Yu, X.-M. Tang, A.F. Miranda, F. Cambi, Z. Grubic, and M.P. King
Hysteresis in Butyrylcholinesterase Catalysis: Evidence for Substrate-Induced Conversion of the Enzyme from Latent to Operative Form, P. Masson, M.-T. Froment, F. Nachon, and L.M. Schopfer
mRNAs Encoding Acetylcholinesterase, Butyrylcholinesterase, and Agrin 19 Share the Same Temporal Pattern of Expression During Development of Rat Spinal Cord, K. Mis, E. Davidson, H. Park, M.P. King, T. Mars, M. Jevsek, M. Brank, and Z. Grubic
New Essential Residues in the Cholinesterase Acyl Pocket, S.N. Moralev
Brain Penetration and Behavioral Properties of a Potent 7 Nicotinic Acetylcholine Receptor Agonist in the Rat, N.A. Moore, D.L. McKinzie, S.N. Mitchell, M. Keenan, D.R. Dobson, G. Wishart, M.F. O'Neill,
TK Murray, B Tree, S Iyengar, J Hart, D Shaw, RMA Simmons, AB Kalra, C Miles, M Conway, J.R. Boot, S.R. Baker, E. Sher, M.D. Tricklebank, and M.J. O'Neill
Dopamine Release from Rat Striatal Slices in vitro and Functional Effects in 6-OHDA-Treated Rats in vivo are Mediated by 2 Nicotinic Acetylcholine Receptors, T.K. Murray, F.A. Jones, E. Tafi, D. Steggles, D.R. Dobson, C.P. Dell, I.A. Pullar and M.J. O'Neill
Hydrocortisone Affects the Densities of Cardiac Muscarinic and Adrenergic Receptors, J. Myslivec?ek, J. R ? ic?ny', and S. Tuc?ek
Fine-Tuning Modulation of Neuronal Muscarinic M1 (Facilitatory) and M2 (Inhibitory) Receptor Activation by Adenosine at the Rat Neuromuscular Junction, L. Oliveira, M.A. Timoteo, and P. Correia-de-Sa
7 Acetylcholine Receptor mRNA in Blood Lymphocytes: A Possible Peripheral Marker for Schizophrenia, O. Perl, T. Ilani, R.D. Strous, R. Lapidus, and S. Fuchs
Effects of Methomyl on Cell Cycle and Apoptosis in Leukocytic Cells, T. Posayanonda, T. Suramana, N. Nuntharatanapong, W. Schwaeble, R. Snowden, N. Dusitsin, R. Sindhuphak, and P. Sinhaseni
Segregation of Phosphatidic Acid-Rich Domains in Reconstituted Acetylcholine Receptor Membranes, J.A. Poveda, J.A. Encinar, A.M. Fernandez, C.R. Mateo, and J.M. Gonzalez-Ros
Muscle Acetylcholinesterase Expression in Hyperthyreotic and Hypothyreotic rats, P. Pregelj and J. Sketelj
Peripheral Binding of Ethopropazine to Horse Serum Butyrylcholinesterase, E. Reiner, G. S ? inko, A. S ? tuglin and V. Simeon-Rudolf
Capillary Zone Electrophoresis Detects Unwanted Cholinesterase-Bound Hidden Ligands that Alter Enzyme Conformational Stability, D. Rochu, F. Renault, C. Bon, and P. Masson
Plant Cholinesterase Activity as a Biosensor: Cellular Models, V.V. Roschchina
Studies on the Mechanism of Blockade of Acetylcholine Release by Snake Presynaptic PLA2 Neurotoxins, O. Rossetto, M. Rigoni, P. Caccin, and C. Montecucco
Variability of Substrate Specificity in Cholinesterases of Vertebrates and Invertebrates, E.V. Rozengart and S.N. Moralev
Overexpression of the Extracellular and Cytoplasmic Domains of the Drosophila Adhesion Protein, gliotactin, E.H. Rydberg, R. Macion, T. Zeev-Ben-Mordehai, A. Solomon, D.M. Rees, L. Toker, S. Botti, V.J. Auld, I. Silman, and J.L. Sussman
Targeting of the Vesicular Acetylcholine Transporter to Cholinergic Subdivisions in Transgenic Mice, B. Schuetz, E. Weihe, and L.E. Eiden
Ligand-Induced Conformational Changes in the Omega Loop of Acetylcholinesterase Revealed by Fluorescence Spectroscopy, J. Shi, Z. Radic', A.E. Boyd, D.A. Johnson, and P. Taylor
'Readthrough' Acetylcholinesterase and Cholinergic Neurotransmission, S. Shoham, E. Kovalev, E. Sklan, and H Soreq
Comparison of Two Reaction Schemes for the Hydrolysis of Acetylthiocholine by Butyrylcholinesterase, V. Simeon-Rudolf, G. S ? inko, A. S ? tuglin, J. Stojan, M. Golic?nik, and E. Reiner
Kinetics of Interaction of Ethopropazine Enantiomers with Butyrylcholinesterase and Acetylcholinesterase, G. S ? inko, Z. Radic', P. Taylor, V. Simeon-Rudolf, and E. Reiner
Two-Hybrid Approach to the Intracellular Function(s) of Readthrough Acetylcholinesterase, E.H. Sklan, K. Birikh, and H. Soreq
Effect of Pyridostigmine Administration on Acetylcholinesterase and Choline Acetyltransferase Activity in Guinea Pig Striatum and Cerebellum, M.E. Smith, M.C. Lintern, C.J. Brewer, and J.R. Wetherell
Effects of Carbamate Insecticides on Rat Neuronal 4 4 Nicotinic Receptors and Rat Brain Acetylcholinesterase, C.J.G.M. Smulders, T.J.H. Bueters, R.G.D.M. van Kleef, and H.P.M. Vijverberg
Calcium Conductance and Choline Sensitivity of Slow Channel Syndrome Acetylcholine Receptor Mutants, I. Spreadbury, R. Webster, D. Beeson, and A. Vincent
Significance of Parameters in Various Kinetic Schemes for Cholinesterases, J. Stojan and M. Golic?nik
Mechanism of Acetylcholinesterase Inhibition by Fasciculin: a 5-ns Molecular Dynamics Simulation, K. Tai, T. Shen, R.H. Henchman, Y. Bourne, P. Marchot, and J.A. McCammon
Interaction between Stress and Pyridostigmine Pretreatment in the Mouse, L. Taysse, I. Delamanche, N. Perrier, and P. Breton
Probing the Binding Interface between the Nicotinic Acetylcholine Receptor and a Short -Neurotoxin through Receptor-Biotinyltoxin-Streptavidin Ternary Complexes, F. Teixeira, A. Menez, and P. Kessler
Huperzine A, A Promising Anti-Alzheimer's Agent, Reduces Staurosporine-Induced Apoptosis in NG108-15 Cells, X.-Q. Xiao, D.-C. Wu, Y. Gao, Y. Fu, N.T.K. Lee, W.-L. Ho, K.W.K. Tsim, and Y.-F. Han
Effects of Lithium Chloride on Memory Performances of Mice in an Elevated Plus-Maze Test, P. Yamantuerk and L. Erog?lu
Effects of 7-Nitroindazole on Memory Performances of Rats Trained for a Three-Panel Runway Task: Hippocampal Cholinergic Enzyme Activities, P. Yamantuerk, Y. UEnluecerci, S. Bekpinar, and H. Koyuncuog?lu
Nicotinic Cholinergic Activation of Magnocellular Endocrine Neurons of the Hypothalamus, M. Zaninetti, E. Tribollet, D. Bertrand, R. Ogier, and M. Raggenbass
Use of the Morphing Graphics Technique to Visualize Conformational Differences between Acetylcholinesterases from Different Species and Inhibitor-Induced Conformational Changes, T. Zeev-Ben-Mordehai, I. Silman, and J.L. Sussman
Neuroprotective Effects of Huperzine A and Donepezil on Staurosporine-Induced Injury in Primary Cortical Neurons, H.Y. Zhang and X.C. Tang
Cloning and Characterization of the Acetylcholinesterase Gene in the Chicken, X. Zhang, R. Choi, K.W.K. Tsim, and D.C.C. Wan