
The Synaptic Organization of the Brain
Gordon M. Shepherd(Editor)
Oxford University Press
5th Edition
Published on 8. January 2004
Book
Paperback/Softback
736 pages
978-0-19-515956-1 (ISBN)
Description
It is widely recognized that the neural basis of brain function can be fully understood only by integrating many disciplines at many levels. Studies os synaptic organization are bringing about a quiet revolution in achieving this goal, as documented by this unique book over the past 30 years. In this fifth edition, the results of the mouse and human genome projects are incorporated for the first time. Molecular biologists interested in functional genomics and proteomics of the brain will find answers here to the critical questions: what are the cell and circuit functions of gene products? Also for the first time, the reader is oriented to supporting neuroscience databases.
Among the new advances covered are 2-photon confocal laser microscopy of dendrites and dendritic spines, biochemical analyses, and dual patch and multielectrode recordings, applied together with an increasing range of behavioural and gene-targeting methods. Leading experts in the best understood brain regions bring together the molecular, anatomical, functional, and behavioural data in authoritative integrated accounts. The chapters are organized in the same format, covering the neural elements, synaptic connections, basic circuits, physiology, neurotransmitters, neuromodulators, membrane properties, dendritic properties, and with a final section on how the circuits mediate specific behaviours. The uniform framework for each chapter enables the authors to higlight the principles that are common to all regions, as well as the adaptations unique to each, thus serving as a model for understanding the neural basis of behaviour.
Among the new advances covered are 2-photon confocal laser microscopy of dendrites and dendritic spines, biochemical analyses, and dual patch and multielectrode recordings, applied together with an increasing range of behavioural and gene-targeting methods. Leading experts in the best understood brain regions bring together the molecular, anatomical, functional, and behavioural data in authoritative integrated accounts. The chapters are organized in the same format, covering the neural elements, synaptic connections, basic circuits, physiology, neurotransmitters, neuromodulators, membrane properties, dendritic properties, and with a final section on how the circuits mediate specific behaviours. The uniform framework for each chapter enables the authors to higlight the principles that are common to all regions, as well as the adaptations unique to each, thus serving as a model for understanding the neural basis of behaviour.
Reviews / Votes
This fifth edition of Shepherd's well-respected text is still worth having on the bookshelf . . . the regions covered are dealt with systematically and clearly. Each chapter has a similar structure, with sections on the neuronal elements present, their synaptic connections and basic circuits, their intrinsic membrane properties, synaptic actions and dendritic properties, and the functional properties of the circuits. This is all done clearly and thoroughly, packing a great deal of information into a small space . . . The synaptic organisation of the brain is a classic text, and still very much worth having and reading for anyone interested in the details of neuroscience. * Physiology News, Number 56 *More details
Edition
5th Revised edition
Language
English
Place of publication
Oxford
United Kingdom
Target group
Professional and scholarly
Senior undergraduates in neuroscience, researchers in neuroscience and neurobiology at all levels
Edition type
Revised edition
Illustrations
numerous line drawings & halftones
Dimensions
Height: 244 mm
Width: 170 mm
Thickness: 39 mm
Weight
1247 gr
ISBN-13
978-0-19-515956-1 (9780195159561)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions

Gordon M. M. D. Shepherd
The Synaptic Organization of the Brain
E-Book
11/2003
5th Edition
OUP eBook
€72.49
Available for download
Previous edition
Gordon M. Shepherd
The Synaptic Organization of the Brain
Book
11/1997
4th Edition
Oxford University Press Inc
€43.33
Article exhausted; check for reprint
Person
Editor
Professor of NeuroscienceProfessor of Neuroscience, Yale University School of Medicine, USA
Content
1. Introduction to Synaptic Circuits ; 2. Membrane Properties and Neurotransmitter Actions ; 3. Spinal Cord: Ventral Horn ; 4. Cochlear Nucleus ; 5. Olfactory Bulb ; 6. Retina ; 7. Cerebellum ; 8. Thalamus ; 9. Basal Ganglia ; 10. Olfactory Cortex ; 11. Hippocampus ; 12. Neocortex