Cell Signaling
Interplay, Mechanisms, and Therapeutic Implications
1st Edition
Published on 16. April 2025
Book
Hardback
412 pages
978-1-032-70744-0 (ISBN)
Description
This book provides a comprehensive understanding of cell signaling, molecular interactions, and their implications for human health and diseases. It introduces fundamental principles underlying cell communication through signaling molecules and their diverse transmission and reception mechanisms, highlighting their role in intercellular communication through voltage- and ion-gated channels, immunological and neuron synapses, and rhinovirus-receptor interaction involved in pathogenesis and disease development. Toward the end, the book highlights the profound implications of altered cell signaling pathways in the inflammation and immune response followed by the progression of various disorders, including cancer, endocrine disorders, and neurological illnesses. It explores the diagnostic and therapeutic implications of cell signaling in targeted therapies, highlighting advanced techniques for detecting signaling molecules and innovative therapeutic approaches to inspire new developments in precision medicine. It serves as an important resource for academics, students, and professionals in the fields of cell biology and biomedical sciences.
Key Features:
Provides in-depth understanding of cell signaling, exploring its complexities and impact on human health and disease
Introduces fundamental principles of cell communication, emphasizing the different signaling molecules and their various transmission pathways
Focuses on complex structures and functions of receptors, highlighting their essential role in intercellular communication and regulating cellular behavior
Examines the molecular aspects of cell surface adhesion receptors, elucidating protein-protein interactions, signaling cascades, and enzyme-substrate interactions
Discusses the impact of cell signaling on inflammation, cancer, and endocrine and neurological disorders
Key Features:
Provides in-depth understanding of cell signaling, exploring its complexities and impact on human health and disease
Introduces fundamental principles of cell communication, emphasizing the different signaling molecules and their various transmission pathways
Focuses on complex structures and functions of receptors, highlighting their essential role in intercellular communication and regulating cellular behavior
Examines the molecular aspects of cell surface adhesion receptors, elucidating protein-protein interactions, signaling cascades, and enzyme-substrate interactions
Discusses the impact of cell signaling on inflammation, cancer, and endocrine and neurological disorders
More details
Language
English
Place of publication
London
United Kingdom
Publishing group
Taylor & Francis Ltd
Target group
College/higher education
Professional and scholarly
Academic, Postgraduate, and Professional Reference
Illustrations
17 s/w Tabellen, 118 farbige Abbildungen, 118 farbige Zeichnungen
17 Tables, black and white; 118 Line drawings, color; 118 Illustrations, color
Dimensions
Height: 260 mm
Width: 183 mm
Thickness: 27 mm
Weight
992 gr
ISBN-13
978-1-032-70744-0 (9781032707440)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
E-Book
04/2025
CRC Press
€251.99
Available for download
E-Book
04/2025
CRC Press
€251.99
Available for download
Person
Dr Adeeb Shehzad is currently Associate Professor at Biodiversity Unit, Research Center, Dhofar University, Oman and OIC of Lab of Biochemistry at Department of Biomedical Engineering and Sciences, SMME, NUST, Pakistan. He obtained his B.Pharmacy from the University of Peshawar, Pakistan in 2003. He completed his MS and Ph.D degree from Kyungpook National University, South Korea (2008-2014). He has published over 100 scientific publications and book chapters in refereed journals. Before joining NUST, Dr Adeeb has worked production pharmacist at Glaxo Smith Kline Pvt Ltd, Karachi, Pakistan and Medicraft Pharmaceutical Pvt Ltd, Peshawar, Pakistan from 2003-2007. His research interest is mainly oriented to the screening and development of plant isolated compounds as anticancer agents, as well as investigating the modulation of different signaling pathways in different types of cancers causing drug resistance and poor prognosis. Dr Adeeb is also interesting in development of kits for diagnosis and drug release patches with validation in animal models. Dr Adeeb is working as Editorial board member for several journals and has authored two books with international publishers. He received a number of national and international awards in academics and research.
Content
1. Introduction to cell signaling
Ishtiaq Ali, Muhammad Junaid, Ahmad Tariq, Fazli Wahid, Muhammad Imran Khan
2. Regulation of Cell Signaling Cascades
Habab Ali Ahmad, Muhammad Ibrahim, Fazli Wahid, Muhammad Imran Khan
3. Cellular Receptors and Cell Signaling
Maleeha Azhar, Aroob Hasan Khan, Aroosa Younis Nadeem, Areej Fatima, Adeeb Shehzad
4. Signal Transduction and Integral Membrane Proteins
Zain Saeed, Zohra Jabeen, Sehrish Kakakhel, Saira Justin, Aneela Javed
5. Antigen-Antibody Interaction in cell signaling
Saman Noor, Anam Fatima, Iman Fatima, Gul Naz, Aneela Javed
6. Immunological and Neuron Synapses
Muhammad Salman Khalid, Somia Mazhar, Adeeb Shehzad
7. Rhinoviruses receptors and their interactions
Areej A. Sattar, Ariba Qaiser, Sobia Manzoor
8. Role of ligand and voltage gated ion channels in cell signaling
Maham Maharangaiz, Hira, sadaf Mumtaz, Rumeza hanif, Aneela Javed
9. Hormones and Receptors Interaction in Cell Signaling
Tehmina Bibi, Shahar Bano, Eun Kyoung Seo, Salman Khan
10. Signaling Networks in Development and Differentiation
Aroosa Younis Nadeem, Areej Fatima, Maleeha Azhar, Adeeb Shehzad
11. Cell Signaling and Metabolism
Saadia Zahid*, Sanila Amber, Laila tul Qadar, Akasha Khurshid
12. Inflammatory Signaling and Immune Response
Naseem Zehra, Zia Uddin, Muhammad Imran Amir Zada, Muhammad Ikram
13. Cell Signaling in Cancer
Khoula Sharif Mughal, Nabi Shah, Muhammad Naeem, Muhammad Ikram
14. Cell signaling pathways in endocrine diseases
Gauhar Rehman, Adil Sher
15. Cell Signaling in Neurological Disorders
Muhammad Ibrar Khan, Muhammad Junaid, Salman Khan
16. Cell Signaling and Diagnosis
Areej Fatima, Ammad Jamil, Maleeha Azhar, Aroosa Younis Nadeem, Adeeb Shehzad
17. Signal Transduction and Targeted Therapies
Ayesha Khan, Ayesha Riaz, Asima Saeed, Muhammad Imran Khan
18. Role of cell signaling in drug development
Taimoor Musharaf, Anoosha Ahmed, Muhammad Asim Siddique, Wajahat Sultan Abbasi, Saadia Andleeb
Ishtiaq Ali, Muhammad Junaid, Ahmad Tariq, Fazli Wahid, Muhammad Imran Khan
2. Regulation of Cell Signaling Cascades
Habab Ali Ahmad, Muhammad Ibrahim, Fazli Wahid, Muhammad Imran Khan
3. Cellular Receptors and Cell Signaling
Maleeha Azhar, Aroob Hasan Khan, Aroosa Younis Nadeem, Areej Fatima, Adeeb Shehzad
4. Signal Transduction and Integral Membrane Proteins
Zain Saeed, Zohra Jabeen, Sehrish Kakakhel, Saira Justin, Aneela Javed
5. Antigen-Antibody Interaction in cell signaling
Saman Noor, Anam Fatima, Iman Fatima, Gul Naz, Aneela Javed
6. Immunological and Neuron Synapses
Muhammad Salman Khalid, Somia Mazhar, Adeeb Shehzad
7. Rhinoviruses receptors and their interactions
Areej A. Sattar, Ariba Qaiser, Sobia Manzoor
8. Role of ligand and voltage gated ion channels in cell signaling
Maham Maharangaiz, Hira, sadaf Mumtaz, Rumeza hanif, Aneela Javed
9. Hormones and Receptors Interaction in Cell Signaling
Tehmina Bibi, Shahar Bano, Eun Kyoung Seo, Salman Khan
10. Signaling Networks in Development and Differentiation
Aroosa Younis Nadeem, Areej Fatima, Maleeha Azhar, Adeeb Shehzad
11. Cell Signaling and Metabolism
Saadia Zahid*, Sanila Amber, Laila tul Qadar, Akasha Khurshid
12. Inflammatory Signaling and Immune Response
Naseem Zehra, Zia Uddin, Muhammad Imran Amir Zada, Muhammad Ikram
13. Cell Signaling in Cancer
Khoula Sharif Mughal, Nabi Shah, Muhammad Naeem, Muhammad Ikram
14. Cell signaling pathways in endocrine diseases
Gauhar Rehman, Adil Sher
15. Cell Signaling in Neurological Disorders
Muhammad Ibrar Khan, Muhammad Junaid, Salman Khan
16. Cell Signaling and Diagnosis
Areej Fatima, Ammad Jamil, Maleeha Azhar, Aroosa Younis Nadeem, Adeeb Shehzad
17. Signal Transduction and Targeted Therapies
Ayesha Khan, Ayesha Riaz, Asima Saeed, Muhammad Imran Khan
18. Role of cell signaling in drug development
Taimoor Musharaf, Anoosha Ahmed, Muhammad Asim Siddique, Wajahat Sultan Abbasi, Saadia Andleeb