The Genetic Basis of Sleep and Sleep Disorders

Preface; Part I. General Principles of Genetics and Genomics: 1. Methods in complex trait analysis: mapping the genetic basis of sleep using model organisms Amelie Baud and Jonathan Flint; 2. Linkage and associations Elizabeth J. Rossin and Benjamin M. Neale; 3. Genome-wide association study approaches to sleep phenotypes Patrick Sleiman, Michael March and Hakon Hakonanson; Part II. Genetics of Sleep and Circadian Rhythms: 4. Genetic epidemiology of sleep and sleep disorders Christer Hublin and Jaakko Kaprio; 5. Drosophlia model systems for genetic sleep research Stephane Dissel and Paul J. Shaw; 6. Caenorhabditis elegans and zebrafish in sleep research David A. Prober and David M. Raizen; 7. Optogenetic control of arousal neurons Antoine Adamantidis, Matthew E. Carter and Luis De Lecea; 8. Prostaglandin D2 in the regulation of sleep Yoshihiro Urade and Michael Lazarus; 9. Astroglial regulation of sleep Marcos G. Frank; 10. The role of metabolic genes in sleep regulation Matthew S. Thimgan and Karen D. Schilli; 11. A systems biology approach for uncovering the genetic landscape for multiple sleep-wake traits Peng Jiang, Andrew Kasarskis, Christopher J. Winrow, John J. Renger and Fred W. Turek; 12. Genetic control of the circadian pacemaker Ethan Buhr and Joseph S. Takahashi; 13. Epigenetic basis of circadian rhythms and sleep disorders Irfan A. Qureshi and Mark F. Mehler; Part III. Sleep Physiology and Homeostasis: 14. Genetics of sleep and EEG Thomas Curie and Mehdi Tafti; 15. Genetic interaction between circadian and homeostatic regulation of sleep Valerie Mongrain and Paul Franken; 16. Genetic approaches to understanding circadian entrainment Till Roenneberg and Karla V. Allebrandt; 17. Animal models for cognitive deficits induced by sleep deprivation Laurent Seugnet and Paul Salin; 18. Individual differences in sleep duration and responses to sleep loss Devon A. Grant and Hans P. A. Van Dongen; 19. Clock polymorphisms associated with human diurnal preference Simon N. Archer and Derk-Jan Dijk; 20. Sleep and long-term memory storage Jennifer H. K. Choi and Ted Abel; 21. Sleep and synaptic homeostasis Chiara Cirelli and Giulio Tononi; Part IV. Insomnias: 22. Heritability and genetic factors in chronic insomnia Yves Dauvilliers and Charles M. Morin; Part V. Narcolepsy and Hypersomnias: 23. HLA and narcolepsy Katsushi Tokunaga and Makoto Honda; 24. Orexin (hypocretin) and narcolepsy Takeshi Sakurai and Seiji Nishino; 25. Gene-wide association studies in narcolepsy Hyun Hor; 26. Genetic disorders producing symptomaric narcolepsy Seiji Nishino and Takashi Kanbayashi; 27. Genetics of recurrent hypersomnia Michael Billiard, Rosa Periata-Adrados and Mehdi Tafti; Part VI. Sleep-related Breathing Disorders: 28. Linkage and candidate gene studies of obstructive sleep apnea Annette C. Fedson, Thorarinn Gislason and Allan I. Pack; 29. Genomic mutations and genotype-phenotype in pediatric sleep-related breathing disorders Leila Kheirandish-Gozal and David Gozal; Part VII. Circadian Rhythm Sleep Disorders: 30. Genetic of familial advanced sleep phase Suet Ying Chong, Louis J. Ptacek and Ying-Hui Fu; 31. Delayed sleep phase disorder, circadian genes, sleep homeostasis and light sensitivity Simon N. Archer and Derk-Jan Dijk; Part VIII. Parasomnias and Sleep-related Movement Disorders: 32. Family and genome-wide association studies of restless legs syndrome Eva C. Schulte and Juliane Winkelmann; Part IX. Psychiatric and Medical Disorders: 33. Circadian clock genes and psychiatric disorders Marc Cuesta, Nicholas Cermakian and Diane B. Boivin; 34. Genetics of autosomnal dominant nocturnal frontal lobe epilepsy Keivan Kaveh Moghadam and Giuseppe Plazzi; Part X. Medication Effects: 35. Gene therapy for sleep disorders Dheeraj Pelluru, RodaRani Konadhode, Carlos Blanco-Centurion, Meng Liu and Priyattam J. Shiromani; Index.