
Stroke Genetics
Springer (Publisher)
Published on 20. September 2014
Book
Paperback/Softback
XX, 320 pages
978-1-4471-6176-9 (ISBN)
Description
Over the last decade there has been a substantial increase in our understanding of the genetic basis of common disorders such as stroke. Stroke Genetics is designed to give the reader an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genome-wide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed. Stroke Genetics benefits from the contribution of renowned experts from throughout the world who have been intimately involved in unraveling the genetic etiology of stroke. Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics.
Reviews / Votes
From the reviews:
"This text reviews genetics of cerebrovascular diseases . . It covers the pathophysiology of occlusive small vessel disease and arteriopathies. It covers Fabry's Disease, Amyloidosis, MELAS, etc., etc. It covers the imaging, pathophysiology, treatment, and complications for ischemia and hemorrhaging. I recommend this text for neurosurgeons, neurologists, physiologists, genetic investigators, and those with an interest in vascular diseases affecting the cerebrum." (Joseph J. Grenier, Amazon.com, May, 2014)More details
Edition
2013 ed.
Language
English
Place of publication
London
United Kingdom
Target group
Adult education
Professional/practitioner
Illustrations
XX, 320 p.
Dimensions
Height: 23.5 cm
Width: 15.5 cm
Weight
5153 gr
ISBN-13
978-1-4471-6176-9 (9781447161769)
DOI
10.1007/978-0-85729-209-4
Schweitzer Classification
Other editions
Additional editions

Pankaj Sharma | James F. Meschia
Stroke Genetics
Book
08/2012
Springer
€181.89
Article exhausted; check for reprint

Pankaj Sharma | James F. Meschia
Stroke Genetics
E-Book
08/2012
1st Edition
Springer
€192.59
Available for download
Persons
Pankaj Sharma, MD, PhD, FRCPReader & Consultant NeurologistImperial College London & Hammersmith HospitalsLondon, UKJames F. Meschia, MDChair, Department of NeurologyMayo Clinic FloridaJacksonville, Florida, USA
Content
Introduction.- Candidate Gene Association Studies in Stroke.- Genome-Wide Association Studies (GWAS).- The Genetics of Cerebral Aneurysms and Other Vascular Malformations.- Intracerebral Hemorrhage and Cerebral Amyloid Angiopathy.- Clinicogenetic and Pathologic Characteristics of CADASIL.- Monogenic Disorder: Fabry Disease.- Stroke-like Episodes in Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes (MELAS).- Genetics of Sickle Cell Disease and Stroke.- Other Monogenetic Stroke Disorders.- White Matter Disease.- Genetics of Carotid Disease.- Genetics of Cervical Artery Dissection.- Stroke Pharmacogenetics.- Ethical Issues in the Genetics of Complex Disorders.