
Hazardous Reagent Substitution
A Pharmaceutical Perspective
Royal Society of Chemistry (Publisher)
Published on 12. December 2017
Book
Hardback
194 pages
978-1-78262-050-1 (ISBN)
Description
In recent years, a significant amount of progress has been made using green chemistry in the synthesis of synthetically useful compounds and molecules by replacing hazardous chemicals with greener alternatives. However, there is still room for improvement, especially in the pharmaceutical sector where new drugs are being formulated. This book examines green approaches to overcoming hazardous organic transformations. Summarizing recent developments, the book features a detailed description of some of the high impact active pharmaceutical ingredients that have been developed considering green chemistry approaches. It explores the design, engineering and process development and the calculations to account for waste. The book includes strategies to further advance green approaches in the development of generic pharmaceutical industries and features novel, innovative approaches that promote waste-free organic synthesis. This book is of interest to industrialists working in pharmaceuticals and researchers working in green chemistry.
More details
Series
Language
English
Place of publication
Cambridge
United Kingdom
Target group
Professional and scholarly
Product notice
Unsewn / adhesive bound
Dimensions
Height: 234 mm
Width: 163 mm
Thickness: 18 mm
Weight
454 gr
ISBN-13
978-1-78262-050-1 (9781782620501)
DOI
10.1039/9781782623847
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions

Rakesh Kumar Sharma | Rakeshwar Bandichhor
Hazardous Reagent Substitution
A Pharmaceutical Perspective
E-Book
11/2017
1st Edition
Royal Society of Chemistry
€205.99
Available for download

Rakesh Kumar Sharma | Rakeshwar Bandichhor
Hazardous Reagent Substitution
A Pharmaceutical Perspective
E-Book
11/2017
1st Edition
Royal Society of Chemistry
€207.99
Available for download
Persons
Rakesh Kumar Sharma is Professor and Coordinator of Green Chemistry Network Centre, University of Delhi, India. Rakeshwar Bandichhor is an Associate Director at Dr. Reddy's Laboratories, India.
Editor
University of Delhi, India
Dr Reddy's Laboratories Ltd, India
Content
Introduction to Hazardous Reagent Substitution in the Pharmaceutical Industry;
Recyclability of Reagents;
Recoverable Polymer-supported DMAP Derivatives;
Synthesis of Atorvastatin;
Synthesis of Raloxifene;
Synthesis of Montelukast;
Development of a Safe, Scalable, Azide-free Synthesis of 1-Aryl-1H-tetrazoles Using Diformylhydrazine;
New Directions from Academia
Recyclability of Reagents;
Recoverable Polymer-supported DMAP Derivatives;
Synthesis of Atorvastatin;
Synthesis of Raloxifene;
Synthesis of Montelukast;
Development of a Safe, Scalable, Azide-free Synthesis of 1-Aryl-1H-tetrazoles Using Diformylhydrazine;
New Directions from Academia