Formation and Regeneration of Nerve Connections
Published in 1992
Book
Hardback
257 pages
978-3-7643-3563-2 (ISBN)
Description
Describes the findings in various aspects of research on the development of the nervous system, in particular the developmental mechanisms pertaining to the creation of order in the visual system. Chapters are written by leaders in their field and comprise views on the emerging strategies for future research, with an emphasis on the consideration of neural specificity and the plasticity of neuronal connections.
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Content
Historical development of the concept of neuronal specificity; development of retinotectal projection in Xenopus; axon pathfinding and the formation of maps in the retinotectal system; in vitro investigations of fibre-fibre and fibre-glial cell interactions in the development of the amphibian visual system; NMDA receptors and intertectal plasticisty in Xenopus; plasticity of binocular visual connections in the frog - from R.M. Gaze to NMDA; experimental manipulation of the developing rodent visual system; refinement of topographic projections in the rodent, avian, amphibian and fish visual systems; pyramidal cell modules in rat visual cortex - their structure and development; architecture fo sensory fibre projections - implications for neuronal specificity in the spinal cord; the conditioned goldfish retinal explant as an experimental model of nerve regeneration; the morphology of developing and regenerating retinal ganglion cels; development of the anuran retina - past and present; activity-driven mechanisms for sharpening retinotopic projections - correlated activity, NMDA receptors, calcium entry and beyond; concerning the logic of growth and form in living systems; three glimpses of evolution; models for the formation of ordered retinotectal connections; neural specificity revisited.