Handbook of Genome Research
Genomics, Proteomics, Metabolomics, Bioinformatics, Ethical and Legal Issues
Published on 10. June 2005
Book
Hardback
XXVIII, 618 pages
978-3-527-31348-8 (ISBN)
Description
In this unique presentation of a revolutionary field of science, the first section introduces the domains of application for genomics and bioinformatics, such as sequencing and the comparative sequence analysis of model organisms, investigating genetically influenced diseases, the development of new active substances, agri-food and environmental genomics.
There then follows an overview of current topics central to DNA technologies, proteomics, metabolomics and bioinformatics, including such hot topics as DNA chip fabrication, yeast two hybrid analysis, tools for gene expression studies, metabolic networks and systems biology.
The whole is rounded off by four chapters on the ethical, legal and social aspects of this sensitive topic.
Reviews / Votes
"...advanced scientists in genome research should find this handbook's chapters, which are...through, to be of value." (CHOICE, April 2006) "This set should be purchased by university libraries interested in genome research and its implications." (American Reference Books Annual, 2006)More details
Edition
1. Auflage
Language
English
Place of publication
Weinheim
Germany
Publishing group
Wiley-VCH
Target group
Professional and scholarly
Biotechnologen, Molekularbiologen, Biochemiker, Biotechnologische Industrie
Illustrations
137
83 s/w Abbildungen, 31 farbige Abbildungen, 23 s/w Tabellen
Dimensions
Height: 24 cm
Width: 17 cm
Thickness: 4.1 cm
Weight
1546 gr
ISBN-13
978-3-527-31348-8 (9783527313488)
Schweitzer Classification
Person
Christoph W. Sensen studied Biology at the Universities of Mainz, Düsseldorf and Köln, Germany. After completing post-doctoral work at the European Molecular Biological Laboratory (EMBL) in Heidelberg he joined the Institute for Marine Biosciences (National Research Council), Canada in 1994. From 1997 to 2001 Christoph Sensen was appointed Project Manager at the Canadian Bioinformatics Resource (CBR-RBC) and took up a full professorship at the University of Calgary, Department of Biochemistry & Molecular Biology in 2001. Christoph Sensen has authored numerous scientific papers and edited two books for Wiley.
HONORS AND AWARDS:
1998 NRC Corporate Outstanding Achievement Award for the Outstanding Contribution to the Canadian Bioinformatics Resource Team
since 06.2002 Fellow of the International Faculty, International Graduate School in Bioinformatics and Genome Research
2003 Computerworld Honors Award
2003 The Duke's Choice Award for Coolest Java Applications and Products at JavaOne 2003
Content
I KEY ORGANISMS
Genome Projects on Model Organisms
Environmental Genomics: A Novel Tool for Study of Uncultivated Microorganisms
Applications of Genomics in Plant Biology
II GENOMIC AND PROTEOMIC TECHNOLOGIES
Human Genetic Diseases
Genomic Mapping and Positional Cloning, with Emphasis on Plant Science
DNA Sequencing Technology
Proteomics and Mass Spectrometry for the Biological Researcher
Proteome Analysis by Capillary Electrophoresis
A DNA Microarray Fabrication Strategy for Research Laboratories
Principles of Application of DNA Microarrays
Yeast Two-hybrid Technologies
Structural Genomics
III BIOINFORMATICS
Bioinformatics Tools for DNA Technology
Software Tools for Proteomics Technologies
Applied Bioinformatics for Drug Discovery and Development
Genome Data Representation Through Images: The MAGPIE/Bluejay System
Bioinformatics Tools for Gene-expression Studies
Protein Interaction Databases
Bioinformatics Approaches for Metabolic Pathways
Systems Biology
IV ETHICAL, LEGAL AND SOCIAL ISSUES
Ethical Aspects of Genome Research and Banking
Biobanks and the Challenges of Commercialization
The (Im)perfect Human - His Own Creator? Bioethics and Genetics at the Beginning of Life
V OUTLOOK
The Future of Large-Scale Life Science Research