
Influenza Models
Prospects for Development and Use
Philip Selby(Editor)
Kluwer Academic Publishers
Published in November 1982
Book
Hardback
259 pages
978-0-85200-459-3 (ISBN)
Description
Kilbourne (1973) described the student of influenza as "continually looking back over his shoulder and asking 'what happened?', in the hope that understanding of past events will alert him to the catastrophies ofthe future". Experience suggests the futility of such a hope, since the most predictable feature of influenza is its unpredictability. Nonetheless, the stubborn viabil ity of this hope is strongly affirmed by the many attempts, described and discussed in this volume, to develop a useful and practical representation of influenza virus behavior. I hasten to add, however, that the desired model has yet to be perfected. The existence and usefulness of animal models of infectious diseases of man are well documented. Reproduction of disease by infecting an experimental animal satisfies the third of Koch's four postulates to establish proof of disease causation by a specific bacterium. Animal models also have been extremely useful in studies of the pathogenesis, immunoprophylaxis, and specific therapy of several important diseases, ineluding (with only modest success) influenza. Development of such a model is simple, at least in concept. and can be achieved by one or only a few scientists.
More details
Language
English
Place of publication
Dordrecht
Netherlands
Publishing group
Kluwer Academic Publishers Group
Target group
College/higher education
Professional and scholarly
Illustrations
45 black & white illustrations, biography
Dimensions
Height: 220 mm
Width: 140 mm
Weight
480 gr
ISBN-13
978-0-85200-459-3 (9780852004593)
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Book
06/2012
Springer
€53.49
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Content
Background paper: Applications of mathematical models to the epidemiology of influenza: a critique.- I. The epidemiology of influenza key facts and remaining problems.- Discussion.- II. Models of the temporal spread of epidemics.- Discussion.- III. Models of family and small community spread.- Discussion.- IV. Relationship of parameters to the real world.- Discussion.- V. Herd immunity.- Discussion.- VI. Models of geographic spread.- Discussion.- VII. Intervention models and vaccine strategy.- Discussion.- VIII. Recommendations.- Participants.