
The Lancet Handbook of Essential Concepts in Clinical Research
Elsevier (Publisher)
Published on 11. April 2006
Book
Paperback/Softback
242 pages
978-0-08-044866-4 (ISBN)
Article exhausted; check for reprint
Description
Building on articles previously published in The Lancet, this handbook is essential for busy clinicians and active researchers interested in research methods in epidemiology.
The needs of clinicians predominate throughout the text, but these needs overlap with those of researchers especially in chapters covering randomized controlled trials. For readers to assess trials accurately they need to understand relevant guidelines on the conduct of trials that are emerging from methodological research. In presenting these discussions to clinicians these chapters will help researchers who also do randomized trials and provide a methodological background that enhances the quality and quantity of their research productivity.
Enables clinicians to read the medical literature more critically
Chapters cover: descriptive studies, cohort studies, case control studies, bias, and screening tests
Five chapters dedicated to randomized controlled trials
The needs of clinicians predominate throughout the text, but these needs overlap with those of researchers especially in chapters covering randomized controlled trials. For readers to assess trials accurately they need to understand relevant guidelines on the conduct of trials that are emerging from methodological research. In presenting these discussions to clinicians these chapters will help researchers who also do randomized trials and provide a methodological background that enhances the quality and quantity of their research productivity.
Enables clinicians to read the medical literature more critically
Chapters cover: descriptive studies, cohort studies, case control studies, bias, and screening tests
Five chapters dedicated to randomized controlled trials
More details
Language
English
Place of publication
London
United Kingdom
Publishing group
Elsevier Health Sciences
Target group
Professional and scholarly
Illustrations
Illustrated
Dimensions
Height: 235 mm
Width: 187 mm
ISBN-13
978-0-08-044866-4 (9780080448664)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
New editions

Kenneth Schulz | David A. Grimes
Essential Concepts in Clinical Research
Randomised Controlled Trials and Observational Epidemiology
Book
09/2018
2nd Edition
Elsevier
€65.79
Shipment within 10-20 days
Content
An overview of clinical research: the lay of the land.
Descriptive studies: what they can and cannot do.
Bias and causal associations in observational research.
Cohort studies: marching towards outcome.
Case-control studies: research in reverse.
Generation of allocation sequences in randomized trials: chance, not choice.
Allocation concealment in randomized trials: defending against deciphering.
Sample size slippages in randomized trials: exclusions and the lost and wayward.
Blinding in randomized trials: hiding who got what.
Uses and abuses of screening tests.
Unequal group sizes in randomized trials: guarding against guessing.
Sample size calculations in randomized trials: mandatory and mystical.
Compared to what? Finding controls for case-control studies.
Refining clinical diagnosis with likelihood ratios.
Multiplicity in randomized trials I: endpoints and treatments.
Multiplicity in randomized trials II: subgroup and interim analyses.
Descriptive studies: what they can and cannot do.
Bias and causal associations in observational research.
Cohort studies: marching towards outcome.
Case-control studies: research in reverse.
Generation of allocation sequences in randomized trials: chance, not choice.
Allocation concealment in randomized trials: defending against deciphering.
Sample size slippages in randomized trials: exclusions and the lost and wayward.
Blinding in randomized trials: hiding who got what.
Uses and abuses of screening tests.
Unequal group sizes in randomized trials: guarding against guessing.
Sample size calculations in randomized trials: mandatory and mystical.
Compared to what? Finding controls for case-control studies.
Refining clinical diagnosis with likelihood ratios.
Multiplicity in randomized trials I: endpoints and treatments.
Multiplicity in randomized trials II: subgroup and interim analyses.