
Drug Delivery
Engineering Principles for Drug Therapy
W. Mark Saltzman(Author)
Oxford University Press Inc
Published on 5. April 2001
Book
Hardback
384 pages
978-0-19-508589-1 (ISBN)
Description
Synthetic materials are a tremendous potential resource for treating human disease. For the rational design of many of these biomaterials it is necessary to have an understanding of polymer chemistry and polymer physics. Equally important to those two fields is a quantitative understanding of the principles that govern rates of drug transport, reaction, and disappearance in physiological and pathological situations. This book is a synthesis of these principles, providing a working foundation for those in the field of drug delivery. It covers advanced drug delivery and contemporary biomaterials.
Reviews / Votes
"Providing a working foundation in the principles underlying drug transport, reaction, and disappearance in physiological and pathological situations, this introduction and guide covers a range of topics, including drug and protein properties, drug modification and diffusion, and polymeric biomaterials. Case studies, physiological guidelines, and useful nomenclature and data are also featured. Saltzman teaches chemical engineering at CornellUniversity."--SciTech Book News
"[A]n excellent addition to the library of any scientist interested in drug delivery systems. Unlike others in the area, this volume is focused on quantitative understanding of the principles that govern rates of drug transport, reaction, and disappearance in physiological conditions. ... even a scientist who may lack a background in mathematics could benefit from this unique discussion of engineering concepts. ... what makes this book outstanding is the
ability of the author to discus mathematical equations grounded in real examples. ... The book is highly recommended as a textbook in the field of drug delivery ..."--The Quarterly Review of Biology
"Providing a working foundation in the principles underlying drug transport, reaction, and disappearance in physiological and pathological situations, this introduction and guide covers a range of topics, including drug and protein properties, drug modification and diffusion, and polymeric biomaterials. Case studies, physiological guidelines, and useful nomenclature and data are also featured. Saltzman teaches chemical engineering at Cornell
University."--SciTech Book News
"[A]n excellent addition to the library of any scientist interested in drug delivery systems. Unlike others in the area, this volume is focused on quantitative understanding of the principles that govern rates of drug transport, reaction, and disappearance in physiological conditions. ... even a scientist who may lack a background in mathematics could benefit from this unique discussion of engineering concepts. ... what makes this book outstanding is the
ability of the author to discus mathematical equations grounded in real examples. ... The book is highly recommended as a textbook in the field of drug delivery ..."--The Quarterly Review of Biology
More details
Series
Language
English
Place of publication
New York
United States
Target group
Professional and scholarly
Illustrations
numerous figures and tables
Dimensions
Height: 240 mm
Width: 161 mm
Thickness: 25 mm
Weight
746 gr
ISBN-13
978-0-19-508589-1 (9780195085891)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions

E-Book
03/2001
1st Edition
OUP eBook
€107.99
Available for download

E-Book
03/2001
1st Edition
OUP eBook
€107.99
Available for download
Person
Author
Professor of Chemical EngineeringProfessor of Chemical Engineering, Cornell University
Content
Part I. Introductory material
1: Introduction
2: Drug administration and drug effectiveness
Part II. Fundamentals
3: Diffusion and drug dispersion
4: Diffusion in biological systems
5: Drug permeation through biological barriers
6: Drug transport by fluid motion
7: Pharmacokinetics of drug distribution
Part III. Drug delivery systems
8: Drug modification
9: Controlled drug delivery systems
10: Case studies in drug delivery
11: Postscript
Appendix A. Overview of polymeric biomaterials
A1. Nondegradable polymers
A2. Biodegradable polymers
A3. Water-soluble polymers
Appendix B. Useful data and nomenclature
B1. Physiological parameters
B2. Cardiovascular system
B3. Clinical chemistry
B4. Permeation and diffusion
B5. Protein properties
B6. Mathematical tables and functions
B7. Nomenclature
Index
1: Introduction
2: Drug administration and drug effectiveness
Part II. Fundamentals
3: Diffusion and drug dispersion
4: Diffusion in biological systems
5: Drug permeation through biological barriers
6: Drug transport by fluid motion
7: Pharmacokinetics of drug distribution
Part III. Drug delivery systems
8: Drug modification
9: Controlled drug delivery systems
10: Case studies in drug delivery
11: Postscript
Appendix A. Overview of polymeric biomaterials
A1. Nondegradable polymers
A2. Biodegradable polymers
A3. Water-soluble polymers
Appendix B. Useful data and nomenclature
B1. Physiological parameters
B2. Cardiovascular system
B3. Clinical chemistry
B4. Permeation and diffusion
B5. Protein properties
B6. Mathematical tables and functions
B7. Nomenclature
Index