Phagocyte and Pathogen Interactions
Macrophages and the Host Response to Infection
1st Edition
Published on 27. July 2009
Book
Hardback
612 pages
978-1-55581-401-4 (ISBN)
Description
* Contains chapters from recognized experts in phagocyte behavior that explore and explain the complex biology behind the roles fulfilled by different phagocyte linages
* Discusses the different cell types, and how they sense and respond to their environment
* Explores the properties and function of the phagosome itself, which is linked intimately with the divergent roles fulfilled by the professional phagocyte lineages
* Includes chapters that explore a variety of different infection models and how the phagocytes respond to control the infection and bolster protective immunity
* Discusses the different cell types, and how they sense and respond to their environment
* Explores the properties and function of the phagosome itself, which is linked intimately with the divergent roles fulfilled by the professional phagocyte lineages
* Includes chapters that explore a variety of different infection models and how the phagocytes respond to control the infection and bolster protective immunity
More details
Content
Table of Contents
Foreword: What Would Darwin Have Said?
Samuel C. Silverstein
Part 1: Biology of the Professional Phagocyte
1. Neutrophils Forever
Taco W. Kuijpers, Timo K. van den Berg, and Dirk Roos
2. Macrophages: Microbial Recognition and Response
Annette Plüddemann and Siamon Gordon
3. Dendritic Cells and Their Tissue Microenvironment during Exposure to Pathogens
A. Mortellaro, F. Granucci, M. Foti, and P. Ricciardi-Castagnoli
Part 2: Membrane Receptors: Recognition, Adhesion, Phagocytosis, Chemotaxis, and Migration
4. Fc Receptors and Phagocytosis
Steven Greenberg and Benjamin M. Dale
5. Chemokines and Phagocyte Trafficking
Timothy J. Williams and Sara M. Rankin
6. Toll-Like Receptors
Ricardo T. Gazzinelli, Kate Fitzgerald, and Douglas T. Golenbock
7. C-Type Lectins: Multifaceted Receptors in Phagocyte Biology
Alessandra Cambi and Carl G. Figdor
8. Integrins on Phagocytes
Wouter L. W. Hazenbos and Eric J. Brown
9. Intracytosolic Sensing of Pathogens: Nucleic Acid Receptors, NLRs, and the Associated Responses during Infections and Autoinflammatory Diseases
Thomas Henry and Denise M. Monack
10. Phagocytes as a Source of the Fluid-Phase Pattern Recognition Receptor PTX3: Interplay between Cellular and Humoral Innate Immunity
Alberto Mantovani, Barbara Bottazzi, Andrea Doni, and Giovanni Salvatori
11. Leukocyte Chemotaxis
Ann Wheeler and Anne J. Ridley
Part 3: Phagocytosis: Signaling, Cytoskeleton, and the Phagosome
12. Signaling for Phagocytosis
Joel A. Swanson
13. Membrane Trafficking during Phagosome Formation and Maturation
Gregory D. Fairn, Elena Gershenzon, and Sergio Grinstein
14. Acidification of Endosomes and Phagosomes
Sushmita Mukherjee and Frederick R. Maxfield
15. Actin-Based Motility in Professional Phagocytes
Frederick S. Southwick
16. Functional Analysis of the Intraphagosomal Environment of the Macrophage: Fluorogenic Reporters and the Transcriptional Responses of Salmonella and Mycobacterium
Robin M. Yates, Kyle H. Rohde, Robert B. Abramovitch, and David G. Russell
Part 4: Bridging the Gap between the Innate and Acquired Immune Response
17. Novel Anti-Inflammatory and Pro-Resolution Lipid Mediators in Induction and Modulation of Phagocyte Function
Charles N. Serhan and Julio Aliberti
18. Cytokines and Macrophages and Dendritic Cells: Key Modulators of Immune Responses
Frank Kaiser and Anne O'Garra
19. Macrophage Classical Activation
Donald C. Vinh and Steven M. Holland
20. The Functional Heterogeneity of Activated Macrophages
Xia Zhang and David M. Mosser
21. Recognition and Removal of Apoptotic Cells
Peter M. Henson and Donna L. Bratton
22. Regulation and Antimicrobial Function of Inducible Nitric Oxide Synthase in Phagocytes
Christian Bogdan
Part 5: Pathogens of the Professional Phagocyte
23. The Multiple Interactions between Salmonella and Phagocytes
Jessica A. Thompson and David W. Holden
24. Legionella, a Pathogen of Amoebae and Macrophages
Michele S. Swanson and Andrew Bryan
25. The Role of Phagocytic Cells during Shigella Invasion of the Colonic Mucosa
Guy Tran Van Nhieu and Philippe Sansonetti
26. Autophagy: a Fundamental Cytoplasmic Sanitation Process Operational in All Cell Types Including Macrophages
Vojo Deretic
27. Brucella, a Perfect Trojan Horse in Phagocytes
Suzana P. Salcedo and Jean-Pierre Gorvel
28. Interaction of Candida albicans with Phagocytes
Inês Faro-Trindade and Gordon D. Brown
29. The Parasite Point of View: Insights and Questions on the Cell Biology of Trypanosoma and Leishmania Parasite-Phagocyte Interactions
Keith Gull
30. Phagocyte Interactions with the Intracellular Protozoan Toxoplasma gondii
Eric Y. Denkers
31. Macrophages in Helminth Infection: Effectors, Regulators, and Wound Healers
Judith E. Allen and Thomas A. Wynn
Part 6: Models of Host-Pathogen Interactions
32. Dictyostelium discoideum: a Model Phagocyte and a Model for Host-Pathogen Interactions
Zhiru Li and Ralph R. Isberg
33. Phagocytosis in Drosophila melanogaster Immune Response
Vincent Leclerc, Jean-Marc Reichhart, Isabelle Caldelari, and Natalia Veresceaghina
34. The Zebrafish as a Model of Host-Pathogen Interactions
J. Muse Davis and Lalita Ramakrishnan
35. Whole Genome Screens in Macrophages
Babak Javid and Eric J. Rubin
Foreword: What Would Darwin Have Said?
Samuel C. Silverstein
Part 1: Biology of the Professional Phagocyte
1. Neutrophils Forever
Taco W. Kuijpers, Timo K. van den Berg, and Dirk Roos
2. Macrophages: Microbial Recognition and Response
Annette Plüddemann and Siamon Gordon
3. Dendritic Cells and Their Tissue Microenvironment during Exposure to Pathogens
A. Mortellaro, F. Granucci, M. Foti, and P. Ricciardi-Castagnoli
Part 2: Membrane Receptors: Recognition, Adhesion, Phagocytosis, Chemotaxis, and Migration
4. Fc Receptors and Phagocytosis
Steven Greenberg and Benjamin M. Dale
5. Chemokines and Phagocyte Trafficking
Timothy J. Williams and Sara M. Rankin
6. Toll-Like Receptors
Ricardo T. Gazzinelli, Kate Fitzgerald, and Douglas T. Golenbock
7. C-Type Lectins: Multifaceted Receptors in Phagocyte Biology
Alessandra Cambi and Carl G. Figdor
8. Integrins on Phagocytes
Wouter L. W. Hazenbos and Eric J. Brown
9. Intracytosolic Sensing of Pathogens: Nucleic Acid Receptors, NLRs, and the Associated Responses during Infections and Autoinflammatory Diseases
Thomas Henry and Denise M. Monack
10. Phagocytes as a Source of the Fluid-Phase Pattern Recognition Receptor PTX3: Interplay between Cellular and Humoral Innate Immunity
Alberto Mantovani, Barbara Bottazzi, Andrea Doni, and Giovanni Salvatori
11. Leukocyte Chemotaxis
Ann Wheeler and Anne J. Ridley
Part 3: Phagocytosis: Signaling, Cytoskeleton, and the Phagosome
12. Signaling for Phagocytosis
Joel A. Swanson
13. Membrane Trafficking during Phagosome Formation and Maturation
Gregory D. Fairn, Elena Gershenzon, and Sergio Grinstein
14. Acidification of Endosomes and Phagosomes
Sushmita Mukherjee and Frederick R. Maxfield
15. Actin-Based Motility in Professional Phagocytes
Frederick S. Southwick
16. Functional Analysis of the Intraphagosomal Environment of the Macrophage: Fluorogenic Reporters and the Transcriptional Responses of Salmonella and Mycobacterium
Robin M. Yates, Kyle H. Rohde, Robert B. Abramovitch, and David G. Russell
Part 4: Bridging the Gap between the Innate and Acquired Immune Response
17. Novel Anti-Inflammatory and Pro-Resolution Lipid Mediators in Induction and Modulation of Phagocyte Function
Charles N. Serhan and Julio Aliberti
18. Cytokines and Macrophages and Dendritic Cells: Key Modulators of Immune Responses
Frank Kaiser and Anne O'Garra
19. Macrophage Classical Activation
Donald C. Vinh and Steven M. Holland
20. The Functional Heterogeneity of Activated Macrophages
Xia Zhang and David M. Mosser
21. Recognition and Removal of Apoptotic Cells
Peter M. Henson and Donna L. Bratton
22. Regulation and Antimicrobial Function of Inducible Nitric Oxide Synthase in Phagocytes
Christian Bogdan
Part 5: Pathogens of the Professional Phagocyte
23. The Multiple Interactions between Salmonella and Phagocytes
Jessica A. Thompson and David W. Holden
24. Legionella, a Pathogen of Amoebae and Macrophages
Michele S. Swanson and Andrew Bryan
25. The Role of Phagocytic Cells during Shigella Invasion of the Colonic Mucosa
Guy Tran Van Nhieu and Philippe Sansonetti
26. Autophagy: a Fundamental Cytoplasmic Sanitation Process Operational in All Cell Types Including Macrophages
Vojo Deretic
27. Brucella, a Perfect Trojan Horse in Phagocytes
Suzana P. Salcedo and Jean-Pierre Gorvel
28. Interaction of Candida albicans with Phagocytes
Inês Faro-Trindade and Gordon D. Brown
29. The Parasite Point of View: Insights and Questions on the Cell Biology of Trypanosoma and Leishmania Parasite-Phagocyte Interactions
Keith Gull
30. Phagocyte Interactions with the Intracellular Protozoan Toxoplasma gondii
Eric Y. Denkers
31. Macrophages in Helminth Infection: Effectors, Regulators, and Wound Healers
Judith E. Allen and Thomas A. Wynn
Part 6: Models of Host-Pathogen Interactions
32. Dictyostelium discoideum: a Model Phagocyte and a Model for Host-Pathogen Interactions
Zhiru Li and Ralph R. Isberg
33. Phagocytosis in Drosophila melanogaster Immune Response
Vincent Leclerc, Jean-Marc Reichhart, Isabelle Caldelari, and Natalia Veresceaghina
34. The Zebrafish as a Model of Host-Pathogen Interactions
J. Muse Davis and Lalita Ramakrishnan
35. Whole Genome Screens in Macrophages
Babak Javid and Eric J. Rubin