Pharmacogenomics
Social, Ethical, and Clinical Dimensions
1st Edition
Published on 30. January 2003
Book
Hardback
384 pages
978-0-471-22769-4 (ISBN)
Description
Through analyses of the complex underlying issues, this interdisciplinary volume frames the agenda for dealing with genetic variation and incorporating pharmacogenomics into health care. The three sections of this book, Research Issues, Clinical Issues, and Social Perspectives address key elements integral to a comprehensive discussion of this emerging field.
This groundbreaking text.
* Examines new research strategies, methodologies, and ethical and social considerations of pharmacogenomics
* Addresses practical considerations of anticipated changes in education, training, oversight, guidelines and protocols, and continuing education requirements
* Provides analyses of the potential enormous impact of pharmacogenomics, such as in the standard of care and treatment, including perspectives from the fields of anthropology, law, ethics, and economics
Reviews / Votes
"The discussion of societal, legal, economic, and governmental issues go well beyond the sphere of pharmogenomics." (American Journal for Medical Genetics, September 1, 2005) "...indispensable guide...as timely as it can be...an impressive multidisciplinary analysis...a 'must read'..." (Bioethics, Vol 18(4), August 2004)"...Pharmacogenomics is highly recommended for anyone with an interest in the field.... Given this book's uniqueness...libraries at any institution teaching pharmcogenomics should have a copy of this book." (Journal of Pharmacy Technology, Sept/Oct 2003)
"...well written, clear, and informative...a restrained sense of excitement...permeates throughout...clearly...a solid contribution to the discourse." (Nature Biotechnology, May 1, 2003)
"...chapters offer fascinating glimpses into fields that may not be familiar to geneticists, genomicists, or clinicians...they will be informative...and provide a reminder that many people outside this field are going to be paying a lot of attention as discoveries...are reported." (New England Journal of Medicine, July 24, 2003)
"...an excellent summary of aspects of phamacogenomics...a solid reference for those working in the field and a unique textbook for those new to the subject area." (Clinical Chemistry, Vol. 49, No. 9)
"...a welcome addition to the growing body of literature...highly recommended for anyone with an interest in the field...should be required reading for anyone conducting pharmacogenomic research and for all clinicians who use pharmacogenomics..." (Journal of Pharmacy Technology, Vol. 19September/October 2003)
"...addresses the ethical, legal, and social implications of the individualized medicine that pharmacogenomics stands to create..." (Genetic Engineering News, Vol 23(14), 2003)
More details
Product info
GB
Edition
1., Auflage
Language
English
Place of publication
New York
United States
Publishing group
John Wiley & Sons Inc
Target group
Professional and scholarly
Product notice
sewn/stitched
Cloth over boards
Illustrations
Drawings: 15 B&W, 0 Color; Tables: 8 B&W, 0 Color
Dimensions
Height: 240 mm
Width: 161 mm
Thickness: 25 mm
Weight
739 gr
ISBN-13
978-0-471-22769-4 (9780471227694)
Schweitzer Classification
Other editions
Additional editions
E-Book
04/2003
Wiley
€115.99
Available for download
Person
Mark A. Rothstein holds the Herbert F. Boehl Chair of Law and Medicine and is Director of the Institute for Bioethics, Health Policy and Law at the University of Louisville. He has appointments in the Departments of Medicine and Family and Community Medicine at the School of Medicine and at the Louis D. Brandeis School of Law. Professor Rothstein is a leading authority on genetics, privacy, and health policy. He has served as an advisor to the NIH, CDC, DOE, Institute of Medicine, National Conference of State Legislatures, and numerous other public and professional entitles.
Content
Foreword (F. Collins).
Preface.
PART I: INTRODUCTION: SCIENCE AND SOCIETY.
Public Attitudes About Pharmacogenomics (M. Rothstein, et al.).
Pharmacogenomics: Pharmacology and Toxicology in the Genomics (H. Mohrenweiser).
The Implications of Population Genetics for Pharmacogenomics (C. Hanis).
PART II: RESEARCH AND DEVELOPMENT CHALLENGES AND CONSIDERATIONS.
Genome Research and Minorities (H. Greely).
Drug Development Strategies (P. Manasco & T. Arledge).
Drug Development, Regulation, and Genetically Guided Therapy Pharmacogenomics (D. Feigal & S. Gutman).
Intellectual Property and Commercial Aspects of Pharmacogenomics (A. Nunnally, et al.).
PART III: CLINICAL APPLICATIONS.
Integration of Pharmacogenomics into Medical Practice (G. Omenn & A. Motulsky).
Clinical Utility Pharmacogenetics and Pharmacogenomics (N. Holtzman).
Medical Liability for Pharmacogenomics (L. Palmer).
The Challenges of Pharmacogenomics for Pharmacy Education, Practice, and Regulation (D. Brushwood).
PART IV: THE SOCIAL DIMENSION.
Economic Implications of Pharmacogenomics (C. Reeder & W. Dickson).
Pharmacogenomics and the Social Construction of Identity (M. Foster).
Pharmacogenomics: Considerations for Communities of Color (L. Nsiah-Jefferson).
Constitutional Issues in the Use of Pharmacogenomic Variations Associated with Race (J. Robertson).
PART V: EPILOGUE: POLICY PRESCRIPTIONS (M. Rothstein).
Pharmacogenomics and Minority Populations: General Population Survey Questionnaire (M. Rothstein).
Index.