Guidebook to the Secretory Pathway

This work aims to enable clinical non-specialists to rapidly gain access to unfamiliar work surrounding the secretory pathways. Detailing both the established and the experimental, the book outlines how recent work has established a role for the secretory pathway in the regulation of gene expression and cell-cycle control. Addressing many aspects of the secretory pathway, the book contains five sections: protein secretion in E.coli; translocation and maturation of newly synthesized polypeptides in the ER of eukaryotic cells; protein machines and catalyzing ER to golgi transport; membrane traffic in the golgi and to the cell surface; and membrane traffic to the lysosome/vacuole.