Experimental and Clinical Aspects of Surfactant Replacement
Selected papers from the European Workshop on Surfactant Replacement, Héviz /Hungary, May 1991. "Biology of the Neonate", Vol 61, Suppl. 1 (1992). Supplement Issue: Neonatology 1992, Vol. 61, Suppl. 1
Published on 14. July 1992
Book
Paperback/Softback
VI, 66 pages
978-3-8055-5644-6 (ISBN)
Description
Surfactant replacement is now an established treatment for neonatal respiratory distress syndrome (RDS), reducing both incidence of complications and mortality. One of the first large randomized trials documenting these effects was reported by the Collaborative European Multicenter Study Group. This group has continued to co-ordinate clinical and experimental work related to surfactant replacement and to arrange annual meetings. The present supplement issue is based on 10 selected presentations from the European Workshop on Surfactant Replacement. The results and ideas presented are of interest to basic investigators in the field as well as to neonatologists who have adopted, or plan to adopt, this new therapeutic approach in their hospitals.
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Content
Preface, B. Robertson, et al; applications of anti-curosurf antibodies to understanding the biology of alveolar surfactant, D.S. Strayer; bubbles and computer-aided image analysis for evaluation on surfactant inhibition, P. Berggren, et al; effectiveness of curosurf for severe respiratory distress syndrome - a case-control study, A. Valls-i-Soler, et al; factors influencing morbidity and mortality in infants with severe respiratory distress syndrome treated with single or multiple doses of a natural porcine surfactant, E. Herting, et al; surfactant administration and the cerebral circulation, L. Skov; modifications of surfactant phospholipid pattern in premature infants treated with curosurf - clinical and dietary correlations, D. Haumont, et al; lung mechanics (FRC and static pressure-volume diagram) after endotracheal surfactant installation - preliminary observations, N.W. Svenningsen; pulmonary functional outcome at one year of age in infants treated with natural procine surfactant at birth, H. Walti, et al; surfactant replacement therapy and the prevalence of acute retinopathy of prematurity, T.R.J. Trubman, et al; estimated costs of different treatments of the respiratory distress syndrome in a large cohort of pre-term infants of less than 30 weeks of gestation, J. Egberts.