
Postgenomics
Perspectives on Biology After the Genome
Duke University Press
Published on 8. May 2015
Book
Paperback/Softback
304 pages
978-0-8223-5894-7 (ISBN)
Description
Ten years after the Human Genome Project's completion the life sciences stand in a moment of uncertainty, transition, and contestation. The postgenomic era has seen rapid shifts in research methodology, funding, scientific labor, and disciplinary structures. Postgenomics is transforming our understanding of disease and health, our environment, and the categories of race, class, and gender. At the same time, the gene retains its centrality and power in biological and popular discourse. The contributors to Postgenomics analyze these ruptures and continuities and place them in historical, social, and political context. Postgenomics, they argue, forces a rethinking of the genome itself, and opens new territory for conversations between the social sciences, humanities, and life sciences.
Contributors. Russ Altman, Rachel A. Ankeny, Catherine Bliss, John DuprE, Michael Fortun, Evelyn Fox Keller, Sabina Leonelli, Adrian Mackenzie, Margot Moinester, Aaron Panofsky, Sarah S. Richardson, Sara Shostak, Hallam Stevens
Contributors. Russ Altman, Rachel A. Ankeny, Catherine Bliss, John DuprE, Michael Fortun, Evelyn Fox Keller, Sabina Leonelli, Adrian Mackenzie, Margot Moinester, Aaron Panofsky, Sarah S. Richardson, Sara Shostak, Hallam Stevens
Reviews / Votes
"The volume is an accessible and insightful collection of critical and informed perspectives on how technological and theoretical developments influence science and society, and how they shape the ways we think about biological systems like ourselves." - Sara Green (Metascience) "Postgenomics suggests just how many questions we may productively ask, and marks some highly fruitful lines of inquiry, as we seek to understand this new chapter in the ongoing interaction among genes, society, and ourselves." - Robin Wolfe Scheffler (Bulletin of the History of Medicine) "The authors convey exceptionally well the character of postgenomic science and how genomics has changed since the 1990s. . . . essential and very interesting reading for anyone interested in genomics and its recent trajectory." - Peter Wade (Technology and Culture) "This book not only analyzes the impact of numerous [genome-wide association studies] but also examines emerging research areas such as epigenetics in political, social, and philosophical contexts, in so doing redefining the information ecology of the genome. Highly recommended." - S. H. Jeong (Choice) "I recommend this book to all biologists and philosophers interested in an accessible overview of the effect of the genomic revolution on the biosciences. It capably discusses both the new discoveries and the technical improvements that have been made since the advent of genomics, as well as the attendant philosophical and sociological implications." - P. William Hughes (Science) "This book . . . should be widely read by all who are interested in the current state and future of the genomic revolution." - Michael Yudell (Social History of Medicine) "[Postgenomics] offers readers an imaginative and frequently playful way to approach the increasingly complicated question about how scientific innovation impacts society and vice versa." - Adrianna Link (Journal of the History of Biology)More details
Language
English
Place of publication
North Carolina
United States
Target group
Professional and scholarly
Product notice
Paperback (trade)
Illustrations
16 illustrations
Dimensions
Height: 229 mm
Width: 152 mm
Thickness: 17 mm
Weight
446 gr
ISBN-13
978-0-8223-5894-7 (9780822358947)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Persons
Sarah S. Richardson is John L. Loeb Associate Professor of the Social Sciences at Harvard University, jointly appointed in the Department of the History of Science and the Committee on Degrees in Studies of Women, Gender, and Sexuality. She is the author of Sex Itself: The Search for Male and Female in the Human Genome.
Hallam Stevens is Assistant Professor of History in the School of Humanities and Social Sciences at Nanyang Technological University (Singapore). He is the author of Life Out of Sequence: A Data-Driven History of Bioinformatics.
Hallam Stevens is Assistant Professor of History in the School of Humanities and Social Sciences at Nanyang Technological University (Singapore). He is the author of Life Out of Sequence: A Data-Driven History of Bioinformatics.
Content
Foreward. Biology's Love Affair with the Genome / Russ Altman vii
1. Beyond the Genome / Hallam Stevens and Sarah S. Richardson 1
2. The Postgenomic Genome / Evelyn Fox Keller 9
3. What Toll Pursuit: Affective Assemblages in Genomics and Postgenomics / Mike Fortun 32
4. The Polygenomic Organism / John DuprE 56
5. Machine Learning and Genomic Dimensionality: From Features to Landscapes / Adrian Mackenzie 73
6. Networks: Representations and Tools in Postgenomics / Hallam Stevens 103
7. Valuing Data in Postgenomic Biology: How Data Donation and Curation Practices Challenge the Scientific Publication System / Rachel A. Ankeny and Sabina Leonelli 126
8. From Behavior Genetics to Postgenomics / Aaron Panofsky 150
9. Defining Health Justice in the Postgenomic Era / Catherine Bliss 174
10. The Missing Piece of the Puzzle? Measuring the Environment in the Postgenomic Moment / Sara Shostak and Margot Moinester 192
11. Maternal Bodies in the Postgenomic Order: Gender and the Explanatory Landscape of Epigenetics / Sarah S. Richardson 210
12. Approaching Postgenomics / Hallam Stevens and Sarah S. Richardson 232
Bibliography 243
Contributors 281
Index 287
1. Beyond the Genome / Hallam Stevens and Sarah S. Richardson 1
2. The Postgenomic Genome / Evelyn Fox Keller 9
3. What Toll Pursuit: Affective Assemblages in Genomics and Postgenomics / Mike Fortun 32
4. The Polygenomic Organism / John DuprE 56
5. Machine Learning and Genomic Dimensionality: From Features to Landscapes / Adrian Mackenzie 73
6. Networks: Representations and Tools in Postgenomics / Hallam Stevens 103
7. Valuing Data in Postgenomic Biology: How Data Donation and Curation Practices Challenge the Scientific Publication System / Rachel A. Ankeny and Sabina Leonelli 126
8. From Behavior Genetics to Postgenomics / Aaron Panofsky 150
9. Defining Health Justice in the Postgenomic Era / Catherine Bliss 174
10. The Missing Piece of the Puzzle? Measuring the Environment in the Postgenomic Moment / Sara Shostak and Margot Moinester 192
11. Maternal Bodies in the Postgenomic Order: Gender and the Explanatory Landscape of Epigenetics / Sarah S. Richardson 210
12. Approaching Postgenomics / Hallam Stevens and Sarah S. Richardson 232
Bibliography 243
Contributors 281
Index 287