Signaling Pathways for Translation
Stress, Calcium, and Rapamycin
Published on 15. December 2010
Book
Paperback/Softback
X, 178 pages
978-3-642-07505-6 (ISBN)
Description
This volume presents the response of the eukaryotic translational apparatus to cellular stress and apoptosis, including kinases activated through both the ERK and stress-activated pathways. It further explores two agents that inhibit protein synthesis, calcium and the immunosuppressant rapamycin. Six chapters written by leading experts in the field provide both new data and comprehensive literature reviews. Both the regulation of initiation and elongation are discussed, and the mechanisms of apoptosis are related to changes in the protein synthesis machinery.
More details
Series
Edition
Softcover reprint of hardcover 1st ed. 2001
Language
English
Place of publication
Berlin
Germany
Publishing group
Springer Berlin
Target group
Professional and scholarly
Research
Illustrations
X, 178 p.
Dimensions
Height: 235 mm
Width: 155 mm
Thickness: 11 mm
Weight
295 gr
ISBN-13
978-3-642-07505-6 (9783642075056)
DOI
10.1007/978-3-662-09889-9
Schweitzer Classification
Other editions
Additional editions
Book
07/2001
Springer
€160.49
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Content
The Regulation of eIF4F During Cell Growth and Cell Death.- Regulation of the Activity of Eukaryotic Initiation Factors in Stressed Cells.- Initiation Factor eIF2? Phosphorylation in Stress Responses and Apoptosis.- Elongation Factor-2 Phosphorylation and the Regulation of Protein Synthesis by Calcium.- Phosphorylation of Mammalian eIF4E by Mnk1 and Mnk2: Tantalizing Prospects for a Role in Translation.- Control of Translation by the Target of Rapamycin Proteins.