Chirality in Drug Design and Development
1st Edition
Published on 15. March 2004
Book
Hardback
464 pages
978-0-8247-5062-6 (ISBN)
Description
Covering every essential element in the development of chiral products, this reference provides a solid overview of the formulation, biopharmaceutical characteristics, and regulatory issues impacting the production of these pharmaceuticals. It supports researchers as they evaluate the pharmacodynamic, pharmacokinetic, and toxicological characteristics of specific enantiomers and chiral drug compounds and addresses in one convenient reference all the major challenges pertaining to drug chirality that have been neglected in the literature. Chirality in Drug Design and Development collects the latest studies from an interdisciplinary team of experts on chiral drug design.
More details
Language
English
Place of publication
Bosa Roca
United States
Publishing group
Taylor & Francis Inc
Target group
Professional and scholarly
Professional
Illustrations
7 s/w Photographien bzw. Rasterbilder
7 Halftones, black and white
Dimensions
Height: 229 mm
Width: 152 mm
Weight
744 gr
ISBN-13
978-0-8247-5062-6 (9780824750626)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Indra K. Reddy | Reza Mehvar
Chirality in Drug Design and Development
E-Book
03/2004
CRC Press
€364.99
Available for download
Indra K. Reddy | Reza Mehvar
Chirality in Drug Design and Development
E-Book
03/2004
1st Edition
CRC Press
€364.99
Available for download
Persons
Indra K. Reddy, Reza Mehvar
Content
Foreword, Fakhreddin Jamali, Preface, Contributors, 1. Effects of Crystal Structure and Physical Properties on the Release of Chiral Drugs, 2. Use of Chiral Excipients in Formulations Containing Chiral Drugs, 3. Transport of Chiral Molecules Across the Skin, 4. Stereoselective Drug Delivery Through Prodrug Approach, 5. Stereoselectivity in Drug Action and Disposition: An Overview, 6. Stereospecific Pharmacokinetics and Pharmacodynamics: Selected Classes of Drugs, 7. Stereospecific Pharmacokinetics and Pharmacodynamics: Cardiovascular Drugs, 8. Chiral Inversion, 9. Bioequivalency Determination of Racemic Drug Formulations: Is Stereospecific Assay Essential?, 10. Regulatory Considerations in Drug Development of Stereoisomers, Index