
Modulating Aging and Longevity
S.I. Rattan(Editor)
Springer (Publisher)
Published on 25. December 2010
Book
Paperback/Softback
VII, 333 pages
978-90-481-6311-3 (ISBN)
Description
After decades of systematic collection of data describing age-related changes in organisms, organs, tissues, cells and macromolecules, biogerontologists are now in a position to construct general principles of ageing and explore various possibilities of intervention using rational approaches. While not giving serious consideration to the claims made by charlatans, it cannot be ignored that several researchers are making genuine attempts to test and develop various means of intervention for the prevention and treatment of age-related diseases, for regaining the functional abilities and for prolonging the lifespan of experimental organisms. This book provides the most up-to-date information and a critical evaluation of a variety of approaches being tried for modulating aging and longevity, including dietary supplementation with antioxidants, vitamins and hormones, genetic engineering, life-style alterations, and hormesis through mild stress. The goal of research on ageing is not to increase human longevity regardless of the consequences, but to increase active longevity free from disability and functional dependence.
More details
Series
Edition
Softcover reprint of hardcover 1st ed. 2003
Language
English
Place of publication
Dordrecht
Netherlands
Target group
Professional and scholarly
Research
Illustrations
15 s/w Abbildungen
VII, 333 p. 15 illus.
Dimensions
Height: 240 mm
Width: 160 mm
Thickness: 19 mm
Weight
551 gr
ISBN-13
978-90-481-6311-3 (9789048163113)
DOI
10.1007/978-94-017-0283-6
Schweitzer Classification
Other editions
Additional editions

S.I. Rattan
Modulating Aging and Longevity
Book
09/2003
Kluwer Academic Publishers
€160.49
Shipment within 15-20 days
Content
1. Modulating aging, longevity determination and the diseases of old age.- 2. The modulation of lifespan by natural selection.- 3. Early-life factors modulating lifespan.- 4. Selective breeding for slower aging and greater lifespan.- 5. Slowing down cellular aging in vitro.- 6. Escaping cellular senescence in vitro.- 7. Stress, cells and tissue aging.- 8. Hormesis in aging and longevity.- 9. Therapeutic interventions for age-related muscle wasting.- 10. Slowing down aging in the skin.- 11. Antioxidants as modulators.- 12. Mitochondrial interventions in aging and longevity.- 13. Hormonal interventions of aging and longevity.- 14. Effect of melatonin on longevity.- 15. Nutritional modulation of aging: effect of caloric restriction.- 16. Small peptide-associated modulation of aging and longevity.- 17. Gene expression profiling to study aging and its modulation.