Progress in Medicinal Chemistry: Volume 40
Volume 40
Elsevier (Publisher)
Published on 25. September 2002
Book
Hardback
149 pages
978-0-444-51054-9 (ISBN)
Description
This volume features accounts of the biological rationale, design and clinical potential of drug molecules; summaries of structure-activity relationships in topical areas of medicinal chemistry and extensive references to the biology, medicinal chemistry and clinical aspects of each topic.
More details
Series
Language
English
Place of publication
Oxford
United Kingdom
Publishing group
Elsevier Science & Technology
Target group
Professional and scholarly
Dimensions
Height: 210 mm
Width: 148 mm
Weight
360 gr
ISBN-13
978-0-444-51054-9 (9780444510549)
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Content
The discovery and development of atorvastatin, a potent novel hypolipidemic agent, B.D. Roth; discovery of CEP-1347/KT-7515, an inhibitor of the JNK/SAPK pathway for the treatment of neurodegenerative diseases, M.S. Saporito, R.L. Hudkins, A.C. Maroney; discovery of second generation quinazolinone non-nucleoside reverse transcriptase inhibitors of HIV-1, J.W. Corbett, J.D. Rodgers; molecular modeling of opioid receptor-ligand complexes, I. McFadyen, T. Metzger, G. Subramanian, G. Poda, E. Jorvig, D.M. Ferguson.