Progress in Medicinal Chemistry: Volume 38
Elsevier (Publisher)
Published on 1. March 2001
Book
Hardback
393 pages
978-0-444-50636-8 (ISBN)
Description
Highlights of this volume include accounts of the biological rationale, design and clinical potential of drug molecules; summaries of structure-activity relationships in topical areas of medicinal chemistry; and evaluation of technologies in their application to drug action and design. The seven chapters describe advances in drug molecules and in the application of new technologies to drug discovery and development.
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Series
Language
English
Place of publication
Oxford
United Kingdom
Publishing group
Elsevier Science & Technology
Target group
College/higher education
Professional and scholarly
ISBN-13
978-0-444-50636-8 (9780444506368)
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Content
p38 kinase - molecular target for the inhibition of proinflammatory cytokines, J.L. Adams et al; the adenosine A3 receptor and its ligands, J.E. Van Muijlwijk-Koezen et al; the medicinal chemistry of the P2 receptor family, S.D. Guile et al; radioligands for the study of brain 5-HT1A receptors "in vivo", V.W. Pike et al; discovery of Montelukast - a once-a-day oral antagonist of leukotriene D4 for the treatment of chronic asthma, R.N. Young; the histamine H3 receptor and its ligands, H. Stark et al; isothermal titration calorimetry in drug discovery, W.H.J. Ward and G.A. Holdgate.