Principles of Gene Manipulation and Genomics
Principles and Applications of Recombinant DNA and Genomics
8th Edition
Published on 20. October 2016
Book
Paperback/Softback
704 pages
978-1-4051-5666-0 (ISBN)
Description
Now in its eighth edition, Principles of Gene Manipulation and Genomics embraces the burgeoning revolution in recombinant DNA technology and its applications. Providing integrated coverage of the techniques used for gene manipulation, genomics, and its related disciplines, the text features full-color illustrations throughout. Chapter summaries and thought-provoking end-of-chapter questions plus a dedicated website provides further instruction and resources for both the student and instructor as well as regular updates on important topics elucidate learning for undergraduate and graduate courses in genetics, genomics, genome analysis, and gene cloning understanding.
Reviews / Votes
"As with previous texts written by Primrose, the subjects are discussed in enough detail to stimulate first to final-year biology and genetics undergraduates and will also help to remind research students about some of the basics they have forgotten." Times Higher Education SupplementMore details
Language
English
Place of publication
Chicester
United Kingdom
Publishing group
John Wiley and Sons Ltd
Target group
Professional and scholarly
Undergraduate and graduate courses in genetics, genomics, genome analysis, and gene cloning.
Dimensions
Height: 276 mm
Width: 219 mm
ISBN-13
978-1-4051-5666-0 (9781405156660)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Classification
Other editions
Previous edition
Sandy B. Primrose | Richard Twyman
Principles of Gene Manipulation and Genomics
Book
01/2006
7th Edition
Wiley
€75.50
Shipment within 3-4 weeks
Persons
Sandy Primrose was an academic for 10 years and a senior manager in the biotechnology industry for 20 years. He now manages a consultancy practice focused on technology management. Richard Twyman was an academic for 9 years and now manages a company that provides expert scientific writing and project management services. He is also a Visiting Fellow at the Department of Biology, University of York.
Content
List of plates. Preface. Abbreviations. 1 Gene manipulation in the post-genomics era. Part I Fundamental Techniques of Gene Manipulation. 2 Basic techniques. 3 Cutting and joining DNA molecules. 4 Basic biology of plasmid and phage vectors. 5 Cosmids, phasmids, and other advanced vectors. 6 Gene-cloning strategies. 7 Sequencing genes and short stretched of DNA. 8 Changing genes: site-directed mutagenesis and protein engineering. 9 Bioinformatics. Part II Manipulating DNA in Microbes, Animals, and Plants. 10 Cloning in bacteria other than Escherichia coli. 11 Cloning in Saccharomyces cerevisiae and other fungi. 12 Gene transfer to animal cells. 13 Genetic manipulation of animals. 14 Gene transfer to plants. 15 Advanced transgenic technology. Part III Genome Analysis, Genomics, and Beyond. 16 The organization and structure of genomes. 17 Mapping and sequencing genomes. 18 Comparative genomics. 19 Large-scale mutagenesis and interference. 20 Analysis of the transcriptome. 21 Proteomics I Expression analysis and characterization of proteins. 22 Proteomics II Analysis of protein structures. 23 Proteomics III Protein interactions. 24 Metabolomics and global biochemical networks. Part IV Applications of Gene Manipulations and Genomics. 25 Applications of genomics: understanding the basis of polygenic disorders and identifying quantitative trait loci. 26 Applications of recombinant DNA technology. Glossary. References. Index