The ATPases
"Mineral and Electrolyte Metabolism", Vol 22, No 5-6 (1996). Special Topic Issue: Vol. 22, No. 5-6 (1996): Mineral and Electrolyte Metabolism
Published on 29. October 1996
Book
Paperback/Softback
IV, 168 pages
978-3-8055-6398-7 (ISBN)
Description
Over the last decade, researchers have learned much about the regulation and structure of the ion pumps most relevant to renal function. This issue provides a comprehensive summary of current knowledge on these critical transport enzymes with particular emphasis on the kidney. The Na,K-pump is examined in six reviews which discuss structure-function relationships, expression and distribution of the pump's various forms within the nephron, its regulation by corticosteroids and the influence of second messengers on its function. Also discussed is the controversy surrounding endogenous circulating inhibitors of the Na,K-ATPase, Na,K-pump inhibition, and the pump's role in ammonium transport within the nephron. Issues relating to calcium transport mechanisms are examined in three reviews, one of which looks at the characteristics of the Ca-ATPase in vascular smooth muscle. The final section contains five reviews which address questions relating to renal acid-base balance and which seek to give new clinical insights by integrating molecular, biochemical, and histologic data.
More details
Language
English
Place of publication
Basel
Switzerland
Target group
College/higher education
Professional and scholarly
Illustrations
45 Abbildungen, 7 Tabellen
1 colored plate, 7 tab.
Dimensions
Height: 25.2 cm
Width: 17.7 cm
Weight
525 gr
ISBN-13
978-3-8055-6398-7 (9783805563987)
Schweitzer Classification
Content
Structure and function of the Na.K-pump - ten years of molecular biology, T.A. Pressley; Na.K-pump expression and distribution in the nephron, N. Farman; Corticosteroid regulation of renal Na.K-ATPase, F. Verrey et al; Direct regulation of the Na.K-pump by signal transduction mechanisms, J.P. Middleton; Endogenous inhibitors of the Na.K-pump, P.A. Doris; Ammonium transport and the role of the Na.K-ATPase, S.M. Wall; Regulation of endoplasmic reticulum-Ca-ATPase by Glycolysis in eukaryotic cells, R. Martinez-Zaguilan, D.E. Wesson; Ca-ATPase and bone cell mineralization, J. Abramowitz, W.N. Suki; Plama membrane and sarcoplasmic reticulum ca-ATPase and smooth muscle, J.M. Gonzalez et al; Renal H,K-ATPase - structure, function, and regulation, B.C.; Biochemical mechanisms and regulation of Hydrogen transport in renal tubules, S. Eiam-Ong, S. Sabatini; Immunocytochemistry of renal H-ATPase, B. Bastani, L. Haragsim; New insights into the pathogenesis of distal renal tubular acidosis, B. Bastani, S.L. Gluck; The renal adenosine triphosphatases - functional integration and clinical significance, M.E. Laski, N.A. Kurtzman.