
Contractile Mechanisms in Muscle
Gerald Pollack(Editor)
Springer (Publisher)
Published on 12. July 2012
Book
Paperback/Softback
XXXII, 921 pages
978-1-4684-4705-7 (ISBN)
Description
Prior to the emergence of the sliding filament model, contraction theories had been in abundance. In the absence of the kinds of structural and biochemical information available today, it has been a simple matter to speculate about the possible ways in which tension generation and shortening might occur. The advent of the sliding filament model had an immediate impact on these theories; within several years they fell by the wayside, and attention was redirected towards mechanisms by which the filaments might be driven to slide by one another. In terms of identifying the driving mechanism, the pivotal observa tion was the electron micrographic indentification of cross-bridges extending from the thick filaments. It was quite naturally assumed that such bridges, which had the ability to split ATP, were the molecular motors, i.e., that they were the sites of mechanochemical transduction. Out of this presumption grew the cross-bridge model. in which filament sliding is presumed to be driven by the cyclic interaction of cross-bridges with complementary actin sites located along the thin filaments.
More details
Series
Edition
Softcover reprint of the original 1st ed. 1984
Language
English
Place of publication
New York
United States
Target group
Professional and scholarly
Research
Illustrations
XXXII, 921 p.
Dimensions
Height: 244 mm
Width: 170 mm
Thickness: 50 mm
Weight
1586 gr
ISBN-13
978-1-4684-4705-7 (9781468447057)
DOI
10.1007/978-1-4684-4703-3
Schweitzer Classification
Other editions
Additional editions

Gerald H. Pollack
Contractile Mechanisms in Muscle
Book
05/1984
Plenum Publishing Corporation
€109.13
Article exhausted; check different version
Content
I: Structural Dynamics.- II: Mechanics, Energetics and Molecular Models.- Participants.