In Situ Hybridization
Published on 1. May 1990
Book
Hardback
260 pages
978-0-19-261906-8 (ISBN)
Description
"In situ" hybridization is a technique of molecular biology that is used to localize the genetic machinery (genes) involved in protein production, by the use of complimentary strands of genetic material (oligonucleotides of DNA or RNA). It is important in the study of the mechanisms underlying cellular function and disease. This book covers all aspects of "in situ" hybridization, from the basic principles of molecular biology, through the various methodological advances, to its most up-to-date applications in pathology.
More details
Language
English
Place of publication
Oxford
United Kingdom
Target group
College/higher education
Professional and scholarly
Illustrations
halftones and line drawings throughout, bibliography
ISBN-13
978-0-19-261906-8 (9780192619068)
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Schweitzer Classification
Other editions
New editions
Book
01/1999
2nd Edition
Oxford University Press
€306.30
Shipment within 15-20 days
Persons
Content
Basic background of molecular biology, V.T-W.Chan et al; principles of "in situ" hybridization, H.Hofler; radioactive labels - autoradiography and choice of emulsions for "in situ" hybridization, M.A.W.Brady and M.A.Finlan; non-radioactive probes - preparation, characterization, and detection, V.T-W.Chan and J.O'D.McGee; oligonucleotide probes for "in situ" hybridization, R.Lathe; principles and applications of complementary RNA probes, S.J.Gibson and J.M.Polak; quantification of radioactive "in situ" hybridization signals, A.P.Davenport and D.J.Nunez; "in situ" hybridization and the study of development, D.G.Wilkinson; "in situ" hybridization in virology, C.G.Teo; chromosomal assignment of genes, B.Bhatt and J.O'D.McGee; interphase cytogenetics of solid tumours, A.H.N.Hopman et al; single and simultaneous nucleic acid detection in archival human biopsies - application of non-isotopic "in situ' hybridization and the polymerase chain reaction to the analysis of human and viral genes, C.S.Herrington et al; photomicrography, S.Bradbury.