Adenosine and Adenine Nucleotides As Regulators of Cellular Function
1st Edition
Published on 14. June 1991
Book
Hardback
456 pages
978-0-8493-6928-5 (ISBN)
Description
This book provides valuable information for investigators interested in the signaling and regulatory functions of adenosine and the adenine nucleotides. Topics covered in this comprehensive volume include the historical development of research on adenosine and adenosine triphosphate; various aspects of the formation, metabolism, release, transport, and receptors for endogenous adenosine and the adenosine triphosphate; functions of purines at the cellular level; the role of adenosine in the regulation of flow in different vascular beds; and angiogenesis. The book also addresses the purinergic regulation of the cardiac, renal, gastro-intestinal, and central nervous system, as well as potential therapeutic avenues for purine use. The book will be valuable to physiologists, pharmacologists, and other basic and clinical scientists interested in updating their knowledge of the expanding biological roles of these substances.
More details
Language
English
Place of publication
Bosa Roca
United States
Publishing group
Taylor & Francis Inc
Target group
College/higher education
Professional and scholarly
Academic and Postgraduate
Illustrations
25 s/w Tabellen
25 Tables, black and white
Dimensions
Height: 254 mm
Width: 178 mm
Weight
1020 gr
ISBN-13
978-0-8493-6928-5 (9780849369285)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
E-Book
12/2024
1st Edition
CRC Press
€767.99
Available for download
E-Book
12/2024
1st Edition
CRC Press
€767.99
Available for download
Person
John W. Phillis
Content
INTRODUCTION. Historical Perspectives-Adenosine (D.J. Cushing and S.J. Mustafa). Historical Perspectives-ATP (D. Satchell). PURINE RECEPTORS, METABOLISM, RELEASE, AND TRANSPORT. Adenosine Receptors: Ligand-Binding Studies (U. Schwabe). Adenosine Receptors, Adenylate Cyclase; Relationships to Pharmacological Actions of Adenosine (R.D. Green). Formation and Metabolism of Adenosine and Adenine Nucleotides in Cardiac Tissue (J. Schrader). Adenosine Deaminase Regulation of Purine Actions (J.D. Geiger, R.A. Padua, and J.I. Nagy). Nucleoside Transport in Cells: Kinetics and Inhibitor Effects (L. Hertz). Adenosine and Adenine Nucleotides in Tissues and Perfusates (T.D. White and K. Hoehn). FUNCTIONS OF PURINES AT THE CELLULAR LEVEL. Adenosine, Adenine Nucleotides and Platelet Function (N.J. Cusack and S.M.O. Hourani). Purines and Inflammation: Neutrophils Possess P1 and P2 Purine Receptors (B.N. Cronstein). Adenosine and Immune System Function (T.S. Priebe and J.A. Nelson). Purinergic Regulation of Transmitter Release (J.A. Ribeiro). ADENOSINE AND BLOOD FLOW IN VASCULAR BEDS. Effect of Adenosine on the Coronary Circulation (M.G. Collis). Purinergic Control of Skeletal Muscle Blood Flow (M.W. Gorman, S.S. Kelley, L. Kaiser, and H.V. Sparks). Adenosine and the Regulation of Cerebral Blood Flow (D.G.L. Van Wylen, V.M. Sciotti, and H.R. Winn). Adenosine and Blood Flow Through the Gastrointestinal Tract (K.G. Proctor and B. Langkamp-Henken). Adenosine-Mediated Regulation of Hepatic Blood Flow (W.E. Lautt). Effects of Adenosine and Adenine Nucleotides on the Pulmonary Circulation (A. Hyman, B. Cai, C. Feng, Q. Hao, and H. Lippton). The Role of Adenosine in Angiogenesis (C.J. Meininger and H.J. Granger). ACTIONS OF ADENOSINE ON BODY SYSTEMS. Influence of Adenosine on Cardiac Activity (M.G. Collis). Adenosine Receptor Activation and Renal Function (W.G. Spielman). Purinergic Regulation of Gastrointestinal Motility and Secretion (M.A. Cook). Effects of Adenosine Infusion on the Cons