Protein Structure and Function
Published on 29. May 2008
Book
Paperback/Softback
218 pages
978-0-19-955684-7 (ISBN)
Description
How does the chemical description of a protein relate to its three-dimensional structure? How does the three-dimensional structure relate to the machinery that brings about a chemical reaction? How does the sequence of a gene encode not only the sequence of a protein but, more importantly, the architecture and function of that protein?
Protein Structure and Function provides a clear and critical survey of our current understanding of the structure and function of proteins to answer questions such as these. Opening with a consideration of the link between protein sequence and structure, it goes on to explore the structural basis of protein function and how this function is controlled. Finally, it examines a range of case studies that illuminate the range of roles performed by proteins, and the diverse structures these proteins exhibit.
Protein Structure and Function combines articulate prose with striking full colour illustrations, while the unique Primers in Biology modular structure integrates text, illustrations, definitions, and literature references for each topic into one double-page spread, bringing to the student's fingertips all the tools that they need to master that topic.
Online Resource Centre
The Online Resource Centre features figures from the book available to download, for registered adopters of the book.
Protein Structure and Function provides a clear and critical survey of our current understanding of the structure and function of proteins to answer questions such as these. Opening with a consideration of the link between protein sequence and structure, it goes on to explore the structural basis of protein function and how this function is controlled. Finally, it examines a range of case studies that illuminate the range of roles performed by proteins, and the diverse structures these proteins exhibit.
Protein Structure and Function combines articulate prose with striking full colour illustrations, while the unique Primers in Biology modular structure integrates text, illustrations, definitions, and literature references for each topic into one double-page spread, bringing to the student's fingertips all the tools that they need to master that topic.
Online Resource Centre
The Online Resource Centre features figures from the book available to download, for registered adopters of the book.
Reviews / Votes
A really good book provides a wealth of information in a manner that the reader remembers what he/she has read. This book does just that. The contents just pop into mind from time to time. This book will be a winner. * Tom Bruice, University of California, Santa Barbara * This treatment and focus is much needed. It will be essential reading by students and faculty alike, and will serve as a crucial reference book for everyone in the biosciences. * James Spudich, Stanford University School of Medicine * It is well-written, makes for interesting reading and contains a number of excellent examples. The whole book appears to be an important, useful and timely one. * Roman Laskowski, European Bioinformatics Institute *More details
Series
Language
English
Place of publication
Oxford
United Kingdom
Target group
Adult education
Illustrations
233 illustrations
Dimensions
Height: 281 mm
Width: 225 mm
Thickness: 17 mm
Weight
509 gr
ISBN-13
978-0-19-955684-7 (9780199556847)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Persons
Gregory A Petsko studied chemistry and classics as an undergraduate at Princeton University before going to Oxford as a Rhodes scholar to work for his PhD with David Phillips. He then pursued his interest in the mechanism of enzyme catalysis at the Massachusetts Institute of Technology where he taught courses in chemistry and detective fiction, before moving to Brandeis where he is currently Director of the Rosenstiel Center and has extended his research interests to include the use of yeast genetics to study the unfolded protein response pathway, and the mechanism of action of the ABC transporter proteins.
Dagmar Ringe graduated in chemistry from Barnard College, Columbia, and took her PhD in bioorganic chemistry from Boston University. She then pursued her research interest in the study of enzyme catalysis by X-ray crystallography at the Massachusetts Institute of Technology before moving to Brandeis where she is Professor of Biochemistry and Chemistry and where the principal focus of her research is on structure-function relationships in enzymes of particular industrial and pharmaceutical importance.
Dagmar Ringe graduated in chemistry from Barnard College, Columbia, and took her PhD in bioorganic chemistry from Boston University. She then pursued her research interest in the study of enzyme catalysis by X-ray crystallography at the Massachusetts Institute of Technology before moving to Brandeis where she is Professor of Biochemistry and Chemistry and where the principal focus of her research is on structure-function relationships in enzymes of particular industrial and pharmaceutical importance.
Content
1. From Sequence to Structure ; 2. From Structure to Function ; 3. Control of Protein Function ; 4. From Sequence to Function: Case Studies in Structural and Functional Genomics ; 5. Structure Determination