Basic Mechanisms of Headache
Published in July 1988
Book
Hardback
518 pages
978-0-444-80955-1 (ISBN)
Description
As we learn more about the the basic mechanisms of headache, it becomes obvious that they are indeed complex, and that no single factor will ever be found which alone can explain migraine or other primary headaches. It is imperative to improve the classification and diagnostic criteria of headache disorders and to study patients in a more systematic way in order to gather reliable information about physiological and biochemical abormalities occurring during headache attacks. The purpose of this book is to present anatomical, physiological and pharmacological knowledge relevant to headache along with actual studies of pathophysiological events in headache patients, thereby bridging the gap between basic science and clinical science.
As we learn more about the the basic mechanisms of headache, it becomes obvious that they are indeed complex, and that no single factor will ever be found which alone can explain migraine or other primary headaches. It is imperative to improve the classification and diagnostic criteria of headache disorders and to study patients in a more systematic way in order to gather reliable information about physiological and biochemical abormalities occurring during headache attacks. The purpose of this book is to present anatomical, physiological and pharmacological knowledge relevant to headache along with actual studies of pathophysiological events in headache patients, thereby bridging the gap between basic science and clinical science.
As we learn more about the the basic mechanisms of headache, it becomes obvious that they are indeed complex, and that no single factor will ever be found which alone can explain migraine or other primary headaches. It is imperative to improve the classification and diagnostic criteria of headache disorders and to study patients in a more systematic way in order to gather reliable information about physiological and biochemical abormalities occurring during headache attacks. The purpose of this book is to present anatomical, physiological and pharmacological knowledge relevant to headache along with actual studies of pathophysiological events in headache patients, thereby bridging the gap between basic science and clinical science.
More details
Series
Language
English
Place of publication
Oxford
United Kingdom
Publishing group
Elsevier Science & Technology
Target group
College/higher education
Professional and scholarly
Dimensions
Height: 250 mm
Width: 210 mm
Weight
1600 gr
ISBN-13
978-0-444-80955-1 (9780444809551)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Classification
Content
Introduction. Section I. Clinical background. Chapter 1. Clinical characterization of migraine (F. Clifford Rose). Chapter 2. Clinical characterization of tension headache (J. Olesen). Chapter 3. Clinical characterization of the cluster headache syndrome (D. Russell). Section II. Basic vascular and nociceptive mechanisms. Part A. Intra- and extracerebral vascular anatomy, physiology and pathophysiology. Chapter 4. Anatomical organization of cerebral and extracerebral vasculature (E. Dahl and L. Edvinsson). Chapter 5. Morphology, physiology and pathophysiology of the blood-brain barrier (G.M. Knudsen, M. Juhler and O.B. Paulson). Chapter 6. Methods for measurement of regional cerebral blood flow (N.A. Lassen and L. Friberg). Chapter 7. Physiology and general pathophysiology of the cerebral circulation (W. Kuschinsky). Chapter 8. Functional activation and inhibition of regional cerebral blood flow and metabolism (L. Friberg and P.E. Roland). Chapter 9. Spreading depression of Leao (A.J. Hansen and M. Lauritzen). Chapter 10. Methods for studying extracerebral blood flow and pulsations with comments on physiology and pathophysiology (S.L. Nielsen and K. Jensen). Part B. Intra- and extracerebral nociceptive mechanisms. Chapter 11. Anatomy and physiology of intra- and extracranial nociceptive afferents and their central projections (T. Yokota). Chapter 12. Nerve supply and receptor mechanisms in intra- and extracerebral blood vessels (L. Edvinsson, E.T. MacKenzie, J. McCulloch and R. Uddmann). Chapter 13. The autonomic innervation of the cephalic circulation (J.E. Brayden and J.A. Bevan). Chapter 14. Do peripheral neuropeptides have a role in extracranial nociception? (L. Edvinsson, I. Jansen, K. Jensen, J. Olesen and R. Uddmann). Chapter 15. Purinergic mechanisms in cerebral circulation (C. Alafaci, K.K. Dhital and G. Burnstock). Chapter 16. Experimental headaches (J. Olesen). Part C. Antinociceptive systems in the central nervous system. Chapter 17. General anatomy of antinociceptive systems (T.S. Jensen and G.F. Gebhart). Chapter 18. Descending inhibition of nociceptive transmission (G.F. Gebhart). Chapter 19. Supraspinal inhibition of nociceptive transmission (T.S. Jensen). Chapter 20. Environmental activation of endogenous antinociceptive systems (D.J. Mayer). Chapter 21. Opioid peptides and substance P in the cerbrospinal fluid. Regulation and significance to pain (F. Nyberg, H. Vaeroy and L. Terenius). Section III. Studies in migraine, tension headache and cluster headache. Part A. Neurotransmitters and hormones. Chapter 22. Opioids in cerebrospinal fluid and blood of headache sufferers (F. Facchinetti and A.R. Genazzani). Chapter 23. Neuropeptides in migraine and cluster headache (L. Edvinsson). Chapter 24. Abnormal sensitivity to neurotransmitter agonists, antagonists and neurotransmitter releasers (F. Sicuteri, M. Nicolodi and B.M. Fusco). Chapter 25. Significance of hormonal changes in primary headache disorders (G. Nappi and E.