
Molecular Evolution and Phylogenetics
Oxford University Press Inc
Published on 27. July 2000
Book
Hardback
336 pages
978-0-19-513584-8 (ISBN)
Description
This book presents the statistical methods that are useful in the study of molecular evolution and illustrates how to use them in actual data analysis. Molecular evolution has been developing at a great pace over the past decade or so, driven by the huge increase in genetic sequence data from many organisms, the improvement of high-speed microcomputers, and the development of several new methods for phylogenetic analysis. This book for graduate students and researchers, assuming a basic knowledge of evolution, molecular biology, and elementary statistics, should make it possible for many investigators to incorporate refined statistical analysis of large-scale data in their own work. Nei is one of the leading workers in this area. He and Kumar have developed a computer program called MEGA, which has been sold for about USD20 to over 1900 users. For the book, the authors are thoroughly revising MEGA and will make it available via FTP. The book also included analysis using the other most popular programs for phylogenetic studies, including PAUP, PHYLIP, MOLPHY, and PAML.
More details
Language
English
Place of publication
New York
United States
Target group
College/higher education
Professional and scholarly
Illustrations
73 colour illustrations
Dimensions
Height: 250 mm
Width: 180 mm
Weight
726 gr
ISBN-13
978-0-19-513584-8 (9780195135848)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Content
Molecular basis of evolution; evolutionary changes of amino acid sequences; evolutionary changes of DNA sequences; synonymous and nonsynonymous nucleotide subsitutions; phylogenetic trees; phylogenetic inference - distance methods; phylogenetic inference - maximum parsimony methods; phylogenetic inference - maximum likelihood methods; accuracies and statistical tests of phylogenetic trees; molecular clocks and linearized trees; ancestral nucleotide and amino acid sequences; genetic polymorphism and evolution; population trees from genetic markers; perspectives. Appendices: mathematical symbols and notations; geological timescale; geological events in the cenozoic and mesozoic eras; evolution of organisms based on the fossil record.